High antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugate

Journal of Surgical Research

Volumn 171, Issue 2, 2011, Pages 684-690

  Ma, Huaiyu ^a   Li, Xiaoming ^a   Yang, Zhijian ^a   Okuno, Satoshi ^b   Kawaguchi, Takayuki ^b   Yagi, Shigeo ^a   Bouvet, Michael ^c   Hoffman, Robert M ^a,c  

^a ANTICANCER INC   (United States)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

camptothecin; efficacy; metastasis; nude mice; orthotopic model; polymer conjugate

Indexed keywords

CAMPTOTHECIN DERIVATIVE; DELIMOTECAN; GREEN FLUORESCENT PROTEIN; IRINOTECAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HT29; COLON CANCER; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BODY WEIGHT; CAMPTOTHECIN; COLONIC NEOPLASMS; DEXTRANS; DOSE-RESPONSE RELATIONSHIP, DRUG; GREEN FLUORESCENT PROTEINS; HT29 CELLS; HUMANS; MICE; MICE, NUDE; PRODRUGS; TOPOTECAN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 81155146090     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.05.066     Document Type: Article

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