Polymorphism at the TRIB1 gene modulates plasma lipid levels: Insight from the Spanish familial hypercholesterolemia cohort study

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 21, Issue 12, 2011, Pages 957-963

  Garcia Rios, A ^a,b   Perez Martinez, P ^a   Mata, P ^c   Fuentes, F ^a   Lopez Miranda, J ^a   Alonso, R ^c   Caballero, J ^d   Mata, N ^c   Perez Jimenez, F ^a   Ordovas, J M ^b  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b TUFTS UNIVERSITY   (United States)

^c Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^d HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Familial hypercholesterolemia; Gene environmental interactions; Lipids; TRIB1 SNP

Indexed keywords

APOA1 PROTEIN, HUMAN; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TRIACYLGLYCEROL; TRIB1 PROTEIN, HUMAN;

ADULT; ARTICLE; BLOOD; COHORT ANALYSIS; CORONARY ARTERY DISEASE; FEMALE; GENETIC ASSOCIATION; GENETICS; HUMAN; HYPERLIPOPROTEINEMIA TYPE 2; MALE; MIDDLE AGED; OBESITY; PATHOPHYSIOLOGY; RISK FACTOR; SENILE ARCH; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SPAIN;

ADULT; APOLIPOPROTEIN A-I; ARCUS SENILIS; CHOLESTEROL, HDL; CHOLESTEROL, LDL; COHORT STUDIES; CORONARY DISEASE; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPIDS; MALE; MIDDLE AGED; OVERWEIGHT; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-SERINE-THREONINE KINASES; RISK FACTORS; SMOKING; SPAIN; TRIGLYCERIDES;

EID: 81155134502     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2010.04.002     Document Type: Article

References (33)

1. Goldstein J.L., Hobbs H.H., Brown M.S. Familial hypercholesterolemia. The metabolic basis of inherited disease 2001, 120:2863-2913. Mc Graw-Hill, New York. C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.).
2. Ferriers J., Lambert J., Lussier-Cacan S., Davignon J. Coronary artery disease in heterozygous familial hypercholesterolemia patients with the same LDL receptor gene mutation. Circulation 1995, 92:290-295.
3. Jansen A., van Aalst-Cohen E., Tanck M., Cheng S., Fontecha M.R., Li J., et al. Genetic determinants of cardiovascular disease risk in familial hypercholesterolemia. Arterioscler Thromb Vasc Biol 2005, 25:1475-1481.
4. Alonso R., Mata N., Castillo S., Fuentes F., Saenz P., Muñiz O., et al. Cardiovascular disease in familial hipercolesterolemia: influence of low-density lipoprotein receptor mutation type and classic risk factors. Atherosclerosis 2008, 200(2):315-321.
5. Perez-Martinez P., Gomez P., Paz E., Marin C., Gavilan Moral E., Lopez-Miranda J., et al. Interaction between smoking and the Sstl polymorphism of the apo C-III gene determines plasma lipid response to diet. Nutr Metab Cardiovasc Dis 2001, 11(4):237-243.
6. Fernandez A., Sorokin A., Thompson P.D. Corneal arcus as coronary artery disease risk factor. Atherosclerosis 2007, 193(2):235-240.
7. Chua B.E., Mitchell P., Wang J.J., Rochtchina E. Corneal arcus and hyperlipidemia: findings from an older population. Am J Ophthalmol 2004, 137(2):363-365.
8. Zech L.A., Hoeg J.M. Correlating corneal arcus with atherosclerosis in familial hypercholesterolemia. Lipids Health Dis 2008, 7:7.
9. van der Net J.B., Oosterveer D.M., Versmissen J., Defesche J.C., Yazdanpanah M., Aouizerat B.E., et al. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Eur Heart J 2008, 29(18):2195-2201.
10. Tanaka T., Shen J., Abecasis G.R., Kisialiou A., Ordovas J.M., Guralnik J.M., et al. Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI study. PLoS Genet 2009 Jan, 5(1):e1000338. Epub 2009 Jan 16].
11. Sung H.Y., Guan H., Czibula A., King A.R., Eder K., Heath E., et al. Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways. J Biol Chem 2007, 282(25):18379-18387.
12. Hegedus Z., Czibula A., Kiss-Toth E. Tribbles: a family of kinase-like proteins with potent signalling regulatory function. Cell Signal 2007, 19(2):238-250.
13. Sung H.Y., Francis S.E., Crossman D.C., Kiss-Toth E. Regulation of expression and signalling modulator function of mammalian tribbles is cell-type specific. Immunol Lett 2006, 104(1-2):171-177.
14. Wang J., Ban M.R., Zou G.Y., Cao H., Lin T., Kennedy B.A., et al. Polygenic determinants of severe hypertriglyceridemia. Hum Mol Genet 2008, 17(18):2894-2899.
15. Kathiresan S., Melander O., Guiducci C., Surti A., Burtt N.P., Rieder M.J., et al. Six new loci associated with blood low-density lipoprotein cholesterol. high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008, 40(2):189-197.
16. Willer C.J., Sanna S., Jackson A.U., Scuteri A., Bonnycastle L.L., Clarke R., et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008, 40(2):161-169.
17. Alonso R., Mata N., Badimon L., Perez-Jimenez F., Mata P. Prognostic factors of cardiovascular disease mortality and morbidity in a cohort of families with genetic diagnoses of familial hypercholesterolemia. Nat Rev Cardiol 2009, 6(4):23-27.
18. Allain C.C., Poon L.S., Chang C.S., Richmond W., Fu P.C. Enzymatic determination of total serum cholesterol. Clin Chem 1974, 20:470-475.
19. Bucolo G., David H. Quantitative determination of serum triglycerides by use of enzymes. Clin Chem 1973, 19:476-482.
20. 2. Clin Chem 1983, 29:2026-2030.
21. Wilson P.W., Zech L.A., Gregg R.E., Schaefer E.J., Hoeg J.M., Sprecher D.L., et al. Estimation of VLDL cholesterol in hyperlipidemia. Clin Chim Acta 1985, 151(3):285-291.
22. Riepponem P., Marniemi J., Rautaoja T. Immunoturbidimetric determination of apolipoproteins A-I and B in serum. Scand J Clin Lab Invest 1987, 47:739-744.
23. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of a preparative ultracentrifugue. Clin Chem 1972, 18:499-502.
24. Tejedor D., Castillo S., Mozas P., Jiménez E., López M., Tejedor M.T., et al. Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia. Clin Chem 2005, 51(7):1137-1144.
25. Livak K.J. Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal 1999, 14:143-149.
26. van den Berg S.W., Dollé M.E., Imholz S., van der A.D.L., van 't Slot R., Wijmenga C., et al. Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study. Int J Obes (Lond) 2009, 33(10):1143-1152.
27. Yang Z., Harrison C.M., Chuang G.C., Ballinger S.W. The role of tobacco smoke induced mitochondrial damage in vascular dysfunction and atherosclerosis. Mutat Res 2007, 621(1-2):61-74.
28. Knight-Lozano C.A., Young C.G., Burow D.L., Hu Z.Y., Uyeminami D., Pinkerton K.E., et al. Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation 2002, 105(7):849-854.
29. Muscat J.E., Harris R.E., Haley N.J., Wynder E.L. Cigarette smoking and plasma cholesterol. Am Heart J 1991, 121(1 Pt 1):141-147.
30. Garcia-Rios A., Perez-Martinez P., Fuentes F., Mata P., Lopez-Miranda J., Alonso R., et al. Genetic variations at ABCG5/G8 genes modulate plasma lipids concentrations in patients with familial hypercholesterolemia. Atherosclerosis 2010, 10.1016/j.atherosclerosis.2010.01.010.
31. Di Luozzo G., Pradhan S., Dhadwal A.K., Chen A., Ueno H., Sumpio B.E. Nicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration. Atherosclerosis 2005, 178(2):271-277.
32. Koch A., Giembycz M., Stirling R.G., Lim S., Adcock I., Wassermann K., et al. Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages. Eur Respir J 2004, 23(6):805-812.
33. Tai E.S., Sim X.L., Ong T.H., Wong T.Y., Saw S.M., Aung T., et al. Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. J Lipid Res 2009 Mar, 50(3):514-520.