Time-dependent effect of chlorhexidine surgical prep

Journal of Hospital Infection

Volumn 79, Issue 4, 2011, Pages 313-316

  Stinner, D J ^a   Krueger, C A ^a   Masini, B D ^a   Wenke, J C ^a  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Chlorhexidine; Surgical site infection

Indexed keywords

AGAR; CHLORHEXIDINE;

ARTICLE; BACTERIAL LOAD; CONTROLLED STUDY; GENETIC ENGINEERING; NONHUMAN; SKIN INCISION; STAPHYLOCOCCUS AUREUS; SURGICAL TECHNIQUE;

ANTI-INFECTIVE AGENTS, LOCAL; BACTERIAL LOAD; CHLORHEXIDINE; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 81055155982     PISSN: 01956701     EISSN: 15322939     Source Type: Journal    
DOI: 10.1016/j.jhin.2011.08.016     Document Type: Article

References (13)

1. Darouiche R.O., Wall M.J., Itani K.M., et al. Chlorhexidine-alcohol versus povidone-iodine for surgical site antisepsis. N Engl J Med 2010, 362:18-26.
2. Bibbo C., Patel D.V., Gehrmann R.M., Linn S.S. Chlorhexidine provides superior skin decontamination in foot and ankle surgery: a prospective randomized study. Clin Orthop Relat Res 2005, 438:204-208.
3. Noorani A., Rabey N., Walsh S.R., Davies R.J. Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery. Br J Surg 2010, 97:1614-1620.
4. Hugo W.B., Longworth A.R. Some aspects of the mode of action of chlorhexidine. J Pharm Pharmacol 1964, 16:655-662.
5. McDonnell G., Russell A.D. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999, 12:147-179.
6. DeBaun B. Evaluation of the antimicrobial properties of an alcohol-free 2% chlorhexidine gluconate solution. AORN J 2008, 87:925-933.
7. Centers for Disease Control and Prevention Guidelines for the prevention of intravascular catheter-related infections. Morb Mortal Wkly Rep 2002, 51(RR10):1-26.
8. Chaiyakunapruk N., Veenstra D.L., Lipsky B.A., Saint S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med 2002, 136:792-801.
9. Caldeira D., David C., Sampaio C. Skin antiseptics in venous puncture-site disinfection for prevention of blood culture contamination: a systematic review with meta-analysis. J Hosp Infect 2011, 77:223-232.
10. Saltzman M.D., Nuber G.W., Gryzlo S.M., Marecek G.S., Koh J.L. Efficacy of surgical preparation solutions in shoulder surgery. J Bone Joint Surg Am 2009, 91:1949-1953.
11. Mangram A.J., Horan T.C., Pearson M.L., Silver L.C., Jarvis W.R. Guidelines for prevention of surgical site infection, 1999: hospital infection control practices advisory committee. Infect Control Hosp Epidemiol 1999, 20:250-278.
12. Patel R., Chavda K.D., Hukkeri S. Surgical field fire and skin burns caused by alcohol-based skin preparation. J Emerg Trauma Shock 2010, 3:305.
13. Batra S., Gupta R. Alcohol based surgical prep solution and the risk of fire in the operating room: a case report. Patient Saf Surg 2008, 2:10.