The HEp-2 cell as target for multiparametric autoantibody analyses: Automation and standardisation;Die HEp-2-Zelle als Target für multiparametrische Autoantikö rperanalytik - Automatisierung und Standardisierung

LaboratoriumsMedizin

Volumn 35, Issue 6, 2011, Pages 351-361

  Hiemann, Rico ^a   Roggenbuck, Dirk ^b   Sack, Ulrich ^c   Anderer, Ursula ^a   Conrad, Karsten ^d  

^a Hochschule Lausitz   (Germany)

^b GA GENERIC ASSAYS GMBH   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

autoantibodies; automation; HEp 2; immunofl uorescence

Indexed keywords

AUTOANTIBODY;

ANALYTICAL EQUIPMENT; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNE HEPATITIS; CALIBRATION; COMPUTER PROGRAM; FLUORESCENCE IMAGING; HEP 2 CELL; HUMAN; HUMAN CELL; LABORATORY AUTOMATION; STAINING; STANDARDIZATION;

EID: 81055147783     PISSN: 03423026     EISSN: 14390477     Source Type: Journal    
DOI: 10.1515/JLM.2011.053     Document Type: Article

References (16)

1. Peene I, Meheus L, Veys EM, De Keyser F. Detection and identification of antinuclear antibodies (ANA) in a large and consecutive cohort of serum samples referred for ANA testing. Ann Rheum Dis 2001;60:1131-6. (Pubitemid 33096077)
2. Worman HJ, Courvalin JC. Antinuclear antibodies specific for primary biliary cirrhosis. Autoimmun Rev 2003;2:211-7. (Pubitemid 36793945)
3. Fritzler MJ. Challenges to the use of autoantibodies as predictors of disease onset, diagnosis and outcomes. Autoimmun Rev 2008; 7:616-20.
4. Damoiseaux JG, Cohen Tervaert JW. From ANA to ENA: how to proceed? Autoimmun Rev 2006;5:10-7.
5. Sordet C, Goetz J, Sibilia J. Contribution of autoantibodies to the diagnosis and nosology of inflammatory muscle disease. Joint Bone Spine 2006;73:646-54. (Pubitemid 44932242)
6. Wiik AS. Anti-nuclear autoantibodies: clinical utility for diagnosis, prognosis, monitoring, and planning of treatment strategy in systemic immunoinflammatory diseases. Scand J Rheumatol 2005;34:260-8. (Pubitemid 41215659)
7. Tozzoli R, Bizzaro N, Tonutti E, Villalta D, Bassetti D, Manoni F, et al. Guidelines for the laboratory use of autoantibody tests in the diagnosis and monitoring of autoimmune rheumatic diseases. Am J Clin Pathol 2002;117:316-24. (Pubitemid 34823674)
8. Wiik A, Gordon TP, Kavanaugh AF, Lahita RG, Reeves W, van Venrooij WJ, et al., and the IUIS/WHO/AF/CDC Committee for the Standardization of Autoantibodies in Rheumatic Diseases. Cutting edge diagnostics in rheumatology: the role of patients, clinicians, and laboratory scientists in optimizing the use of autoimmune serology. Arthritis Rheum (Arthr Care Res) 2004;51:291-8. (Pubitemid 38468717)
9. Holborow EJ, Weir DM, Johnson GD. A serum factor in lupus erythematosus with affinity for tissue nuclei. Br J Med 1957;2:732-4.
10. Conrad K, Schöler W, Hiepe F.Autoantikörper bei systemischen Autoimmunerkrankungen. Ein diagnostischer Leitfaden. 3. Auflage, Pabst Science Publishers, Lengerich, 2006.
11. Hiemann R, Hilger N, Michel J, Nitschke J, Böhm A, Anderer U, et al. Automatic analysis of immunofluorescence patterns of HEp-2 cells. Ann NY Acad Sci 2007;1109:358-71. (Pubitemid 47511379)
12. Hiemann R, Büttner T, Krieger T, Roggenbuck D, Sack U, Conrad K. Challenges of automated screening and differentiation of non-organ specific autoantibodies on HEp-2 cells. Autoimmun Rev 2009;9:17-22.
13. Kang I, Siperstein R, Quan T, Breitenstein ML. Utility of age, gender, ANA titer and pattern as predictors of anti-ENA and-dsDNA antibodies. Clin Rheumatol 2004;23:509-15. (Pubitemid 39562257)
14. Egerer K, Roggenbuck D, Hiemann R, Weyer MG, Büttner T, Radau B, et al. Automated evaluation of autoantibodies on human epithelial-2 cells as an approach to standardize cell-based immunofluorescence tests. Arthritis Res Ther 2010;12:R40. Epub 2010 Mar 9.
15. Enarson P, Rattner JB, Ou Y, Miyachi K, Horigome T, Fritzler MJ. Autoantigens of the nuclear pore complex. J Mol Med 2004;82:423-33. (Pubitemid 39044282)
16. Miyachi K, Hankins RW, Matsushima H, Kikuchi F, Inomata T, Horigome T, et al. Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis: a multicenter study. J Autoimmun 2003;20: 247-54. (Pubitemid 36561490)