A dimethyl ketal-protected benzoin-based linker suitable for photolytic release of unprotected peptides

Journal of Organic Chemistry

Volumn 76, Issue 22, 2011, Pages 9409-9416

  Chumachenko, Nataliya ^a   Novikov, Yehor ^a   Shoemaker, Richard K ^a   Copley, Shelley D ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE BOND FORMATION; AQUEOUS MEDIA; CARBONYL GROUPS; MILD ACIDIC CONDITIONS; SIDE PRODUCTS; SOLID PHASE PEPTIDE SYNTHESIS; SOLID-PHASE; SYNTHETIC PROCEDURES; SYNTHETIC ROUTES; TETHERED MOLECULES; UV IRRADIATION;

AMIDES; DICHLOROMETHANE; IRRADIATION; PEPTIDES;

COLUMN CHROMATOGRAPHY;

1,3 DITHIANE DERIVATIVE; 3 (1,3 DITHIAN 2 YL)BENZOIC ACID; 3 [1,1 DIMETHOXY 2 TERT BUTYLDIMETHYLSILYLOXY 2 (3,5 DIMETHOXYPHENYL)ETHYL]BENZOIC ACID; 3 [2 [HYDROXY(3,5 DIMETHOXYPHENYL)METHYL] 1,3 DITHIAN 2 YL]BENZOIC ACID; 3 [2 [TERT BUTYLDIMETHYLSILYLOXY(3,5 DIMETHOXYPHENYL)METHYL] 1,3 DITHIAN 2 YL]BENZOIC ACID; 3 [2 [TERT BUTYLDIMETHYLSILYLOXY(3,5 DIMETHOXYPHENYL)METHYL] 1,3 DITHIAN 2 YL]BENZOIC ACID TERT BUTYLDIMETHYLSILYL ESTER; 3',5' DIMETHOXYBENZOIN; ACETAL; AMIDE; BENZOIN; CARBONYL DERIVATIVE; DICHLOROMETHANE; DIMETHYL KETAL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; COLUMN CHROMATOGRAPHY; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTOLYSIS; SOLID PHASE SYNTHESIS; ULTRAVIOLET IRRADIATION;

BENZOIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PEPTIDES; PHOTOLYSIS; SOLID-PHASE SYNTHESIS TECHNIQUES;

EID: 81055144529     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo2017263     Document Type: Article

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