Cdc42 Regulates Multiple Membrane Traffic Events in Fission Yeast

Traffic

Volumn 12, Issue 12, 2011, Pages 1744-1758

  Estravís, Miguel ^a   Rincón, Sergio A ^a   Santos, Beatriz ^a   Pérez, Pilar ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Cdc42; Cell morphogenesis; Cell polarity; Exocyst; Fission yeast; Membrane traffic; Secretion

Indexed keywords

ACID PHOSPHATASE; FUNGAL PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; PROTEIN POB1; PROTEIN PSY1; PROTEIN RHO3; SCAFFOLD PROTEIN; SYNTAXIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CELL VACUOLE; FUNGAL STRAIN; FUNGUS GROWTH; GENE OVEREXPRESSION; HEAT SENSITIVITY; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE;

ACID PHOSPHATASE; ACTINS; ALLELES; CARBOXYPEPTIDASES; CDC42 GTP-BINDING PROTEIN; CELL MEMBRANE; CELL POLARITY; ENDOSOMES; EXOCYTOSIS; GENE EXPRESSION REGULATION, FUNGAL; GTP PHOSPHOHYDROLASES; MEMBRANE FUSION; MEMBRANE TRANSPORT PROTEINS; PROTEIN TRANSPORT; QA-SNARE PROTEINS; RAB GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SNARE PROTEINS; VACUOLES;

EID: 81055125470     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2011.01275.x     Document Type: Article

References (63)

1. Park HO, Bi E. Central roles of small GTPases in the development of cell polarity in yeast and beyond. Microbiol Mol Biol Rev 2007;71:48-96.
2. Perez P, Rincon SA. Rho GTPases: regulation of cell polarity and growth in yeasts. Biochem J 2010;426:243-253.
3. Ridley AJ. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 2006;16:522-529.
4. Brennwald P, Rossi G. Spatial regulation of exocytosis and cell polarity: yeast as a model for animal cells. FEBS Lett 2007;581:2119-2124.
5. Zhao ZS, Manser E. PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation. Biochem J 2005;386:201-214.
6. Takenawa T, Suetsugu S. The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. Nat Rev Mol Cell Biol 2007;8:37-48.
7. Faix J, Grosse R. Staying in shape with formins. Dev Cell 2006;10:693-706.
8. Rincon SA, Ye Y, Villar-Tajadura MA, Santos B, Martin SG, Perez P. Pob1 participates in the Cdc42 regulation of fission yeast actin cytoskeleton. Mol Biol Cell 2009;20:4390-4399.
9. Wu H, Rossi G, Brennwald P. The ghost in the machine: small GTPases as spatial regulators of exocytosis. Trends Cell Biol 2008;18:397-404.
10. Feierbach B, Chang F. Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division. Curr Biol 2001;11:1656-1665.
11. Martin SG, Rincon SA, Basu R, Perez P, Chang F. Regulation of the formin for3p by cdc42p and bud6p. Mol Biol Cell 2007;18:4155-4167.
12. Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, Peter M, Boone C. Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 1997;276:118-122.
13. Ozaki-Kuroda K, Yamamoto Y, Nohara H, Kinoshita M, Fujiwara T, Irie K, Takai Y. Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae. Mol Cell Biol 2001;21:827-839.
14. He B, Guo W. The exocyst complex in polarized exocytosis. Curr Opin Cell Biol 2009;21:537-542.
15. Roumanie O, Wu H, Molk JN, Rossi G, Bloom K, Brennwald P. Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex. J Cell Biol 2005;170:583-594.
16. Guo W, Roth D, Walch-Solimena C, Novick P. The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J 1999;18:1071-1080.
17. Zhang X, Bi E, Novick P, Du L, Kozminski KG, Lipschutz JH, Guo W. Cdc42 interacts with the exocyst and regulates polarized secretion. J Biol Chem 2001;276:46745-46750.
18. Wu H, Turner C, Gardner J, Temple B, Brennwald P. The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis. Mol Biol Cell 2010;21:430-442.
19. Ory S, Gasman S. Rho GTPases and exocytosis: what are the molecular links? Semin Cell Dev Biol 2011;22:27-32.
20. Tatebe H, Nakano K, Maximo R, Shiozaki K. Pom1 DYRK regulates localization of the Rga4 GAP to ensure bipolar activation of Cdc42 in fission yeast. Curr Biol 2008;18:322-330.
21. Miller PJ, Johnson DI. Cdc42p GTPase is involved in controlling polarized growth in Schizosaccharomyces pombe. Mol Cell Biol 1994;14:1075-1083.
22. Wang H, Tang X, Liu J, Trautmann S, Balasundaram D, McCollum D, Balasubramanian MK. The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe. Mol Biol Cell 2002;13:515-529.
23. Abe M, Qadota H, Hirata A, Ohya Y. Lack of GTP-bound Rho1p in secretory vesicles of Saccharomyces cerevisiae. J Cell Biol 2003;162:85-97.
24. Wang H, Tang X, Balasubramanian MK. Rho3p regulates cell separation by modulating exocyst function in Schizosaccharomyces pombe. Genetics 2003;164:1323-1331.
25. Nakano K, Imai J, Arai R, Toh EA, Matsui Y, Mabuchi I. The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast. J Cell Sci 2002;115:4629-4639.
26. Forsburg SL. Comparison of Schizosaccharomyces pombe expression systems. Nucleic Acids Res 1993;21:2955-2956.
27. Sivaram MV, Saporita JA, Furgason ML, Boettcher AJ, Munson M. Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p. Biochemistry 2005;44:6302-6311.
28. +)-encoding syntaxin-like protein. Mol Biol Cell 2001;12:3955-3972.
29. Gurunathan S, Chapman-Shimshoni D, Trajkovic S, Gerst JE. Yeast exocytic v-SNAREs confer endocytosis. Mol Biol Cell 2000;11: 3629-3643.
30. Edamatsu M, Toyoshima YY. Fission yeast synaptobrevin is involved in cytokinesis and cell elongation. Biochem Biophys Res Commun 2003;301:641-645.
31. Goud B, Salminen A, Walworth NC, Novick PJ. A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast. Cell 1988;53:753-768.
32. Grosshans BL, Andreeva A, Gangar A, Niessen S, Yates JR III, Brennwald P, Novick P. The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. J Cell Biol 2006;172:55-66.
33. Gao XD, Albert S, Tcheperegine SE, Burd CG, Gallwitz D, Bi E. The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 2003;162:635-646.
34. Muller O, Johnson DI, Mayer A. Cdc42p functions at the docking stage of yeast vacuole membrane fusion. EMBO J 2001;20: 5657-5665.
35. Eitzen G, Thorngren N, Wickner W. Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking. EMBO J 2001;20:5650-5656.
36. Gachet Y, Hyams JS. Endocytosis in fission yeast is spatially associated with the actin cytoskeleton during polarised cell growth and cytokinesis. J Cell Sci 2005;118:4231-4242.
37. Iwaki T, Hosomi A, Tokudomi S, Kusunoki Y, Fujita Y, Giga-Hama Y, Tanaka N, Takegawa K. Vacuolar protein sorting receptor in Schizosaccharomyces pombe. Microbiology 2006;152:1523-1532.
38. Miyatake M, Kuno T, Kita A, Katsura K, Takegawa K, Uno S, Nabata T, Sugiura R. Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast. Genetics 2007;175:1695-1705.
39. Conibear E, Stevens TH. Studying yeast vacuoles. Methods Enzymol 2002;351:408-432.
40. Novick P, Field C, Schekman R. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 1980;21:205-215.
41. Kita A, Li C, Yu Y, Umeda N, Doi A, Yasuda M, Ishiwata S, Taga A, Horiuchi Y, Sugiura R. Role of the small GTPase Rho3 in Golgi/endosome trafficking through functional interaction with adaptin in fission yeast. PLoS One 2011;6:e16842.
42. Adamo JE, Moskow JJ, Gladfelter AS, Viterbo D, Lew DJ, Brennwald PJ. Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J Cell Biol 2001;155:581-592.
43. Adams AE, Johnson DI, Longnecker RM, Sloat BF, Pringle JR. CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol 1990;111:131-142.
44. Ziman M, O'Brien JM, Ouellette LA, Church WR, Johnson DI. Mutational analysis of CDC42Sc, a Saccharomyces cerevisiae gene that encodes a putative GTP-binding protein involved in the control of cell polarity. Mol Cell Biol 1991;11:3537-3544.
45. Wu H, Brennwald P. The function of two Rho family GTPases is determined by distinct patterns of cell surface localization. Mol Cell Biol 2010;30:5207-5217.
46. Irazoqui JE, Gladfelter AS, Lew DJ. Scaffold-mediated symmetry breaking by Cdc42p. Nat Cell Biol 2003;5:1062-1070.
47. Nakano K, Toya M, Yoneda A, Asami Y, Yamashita A, Kamasawa N, Osumi M, Yamamoto M. Pob1 ensures cylindrical cell shape by coupling two distinct Rho signaling events during secretory vesicle targeting. Traffic 2011;12:726-739.
48. Bendezu FO, Martin SG. Actin cables and the exocyst form two independent morphogenesis pathways in the fission yeast. Mol Biol Cell 2011;22:44-53.
49. Zhang XM, Ellis S, Sriratana A, Mitchell CA, Rowe T. Sec15 is an effector for the Rab11 GTPase in mammalian cells. J Biol Chem 2004;279:43027-43034.
50. Oztan A, Silvis M, Weisz OA, Bradbury NA, Hsu SC, Goldenring JR, Yeaman C, Apodaca G. Exocyst requirement for endocytic traffic directed toward the apical and basolateral poles of polarized MDCK cells. Mol Biol Cell 2007;18:3978-3992.
51. Zhang X, Wang P, Gangar A, Zhang J, Brennwald P, TerBush D, Guo W. Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol 2005;170:273-283.
52. Hattendorf DA, Andreeva A, Gangar A, Brennwald PJ, Weis WI. Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature 2007;446:567-571.
53. Ma Y, Takeuchi M, Sugiura R, Sio SO, Kuno T. Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast. Genes Cells 2009;14:1015-1028.
54. Harris KP, Tepass U. Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis. J Cell Biol 2008;183:1129-1143.
55. Kita A, Sugiura R, Shoji H, He Y, Deng L, Lu Y, Sio SO, Takegawa K, Sakaue M, Shuntoh H, Kuno T. Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast. Mol Biol Cell 2004;15:2920-2931.
56. Cheng H, Sugiura R, Wu W, Fujita M, Lu Y, Sio SO, Kawai R, Takegawa K, Shuntoh H, Kuno T. Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. Mol Biol Cell 2002;13:2963-2976.
57. Prigent M, Dubois T, Raposo G, Derrien V, Tenza D, Rosse C, Camonis J, Chavrier P. ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol 2003;163:1111-1121.
58. Moreno S, Klar A, Nurse P. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 1991;194:795-823.
59. Ito H, Fukuda Y, Murata K, Kimura A. Transformation of intact yeast cells treated with alkali cations. J Bacteriol 1983;153:163-168.
60. Bähler J, Wu J-Q, Longtine MS, Shah NG, McKenzie III A, Steever AB, Wach A, Philippsen P, Pringle JR. Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 1998;14:943-951.
61. Coll PM, Trillo Y, Ametzazurra A, Perez P. Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe. Mol Biol Cell 2003;14:313-323.
62. Arellano M, Duran A, Perez P. Localization of the Schizosaccharomyces pombe rho1 GTPase and its involvement in the organization of the actin cytoskeleton. J Cell Sci 1997;110:2547-2555.
63. Roberts CJ, Raymond CK, Yamashiro CT, Stevens T. Methods for studying the yeast vacuole. Methods Enzymol 1991;194:644-661.