ARB treatment prevents the decrease in endothelial progenitor cells and the loss of renal microvasculature in remnant kidney

American Journal of Nephrology

Volumn 33, Issue 6, 2011, Pages 550-557

  Yu, Yi ^a   Wang, Yan ^a   Zhou, Li Na ^a   Zheng, Feng ^a  

^a FUZHOU GENERAL HOSPITAL   (China)

Author keywords

Angiotensin; Epithelial cell injury; Glomerulosclerosis; Vascular endothelial growth factor

Indexed keywords

CD31 ANTIGEN; CD34 ANTIGEN; LOSARTAN; THROMBOSPONDIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CELL LOSS; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; GLOMERULUS; KIDNEY BLOOD VESSEL; KIDNEY TUBULE; MALE; MICROVASCULATURE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ADULT STEM CELLS; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOOD CELLS; CAPILLARIES; ENDOTHELIAL CELLS; KIDNEY; LOSARTAN; MALE; NEPHRECTOMY; RATS; RATS, SPRAGUE-DAWLEY; THROMBOSPONDIN 1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80955173858     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000328632     Document Type: Article

References (29)

1. Kang DH, Kanellis J, Hugo C, Truong L, Anderson S, Kerjaschki D, Schreiner GF, Johnson RJ: Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol 2002; 13:806-816. (Pubitemid 34183950)
2. Molitoris BA, Sutton TA: Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int 2004;66: 496-499. (Pubitemid 38981985)
3. Ostendorf T, Kunter U, Eitner F, Loos A, Regele H, Kerjaschki D, Henninger DD, Janjic N, Floege J: VEGF(165) mediates glomerular endothelial repair. J Clin Invest 1999; 104: 913-923. (Pubitemid 29536341)
4. Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
5. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM: Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997;275:964-967. (Pubitemid 27087709)
6. Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magner M, Isner JM: Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999;85: 221-228. (Pubitemid 29377293)
7. Imanishi T, Moriwaki C, Hano T, Nishio I: Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension. J Hypertens 2005;23:1831-1837. (Pubitemid 41830423)
8. Tongesrs J, Losordo DW: Frontiers in nephrology: the evolving therapeutic applications of endothelial progenitor cells. J Am Soc Nephrol 2007; 18:2843-2852. (Pubitemid 350058390)
9. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, Finkei T: Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003;348:593-600. (Pubitemid 36204953)
10. Vasa M, Fichtischerer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, Dimmeler S: Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001;89:E1-E7.
11. Deng A, Arndt MA, Satriano J, Singh P, Rieg T, Thomson S, Tang T, Blantz RC: Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade. Am J Physiol Renal Physiol 2010; 299:F1365-F1373.
12. Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, Atkins RC, Rohde R, Raz I: Renoprotective effect of the angio-tensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-860.
13. Liang XB, Ma LJ, Naito T, Wang Y, Madaio M, Zent R, Pozzi A, Fogo AB: Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth. J Am Soc Nephrol 2006; 17: 1886-1895. (Pubitemid 44036173)
14. Walter DH, Rittig K, Bahlmann FH, Kirchmair R, Silver M, Murayama T, Nishimura H, Losordo DW, Asahara T, Isner JM: Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 2002; 105:3017-3024. (Pubitemid 34693836)
15. Pillebout E, Burtin M, Yuan HT, Briand P, Woolf AS, Friedlander G, Terzi F: Proliferation and remodeling of the peritubular microcirculation after nephron reduction. Am J Physiol 2001;159:547-560.
16. Ulger H, Karabulut AK, Pratten MK: Labelling of rat endothelial cells with antibodies to vWF, RECA-1, PECAM-1, ICAM-1, OX-43 and ZO-1. Anat Histol Embryol 2002;31:31-35.
17. Matsui K, Nagy-Bojarsky K, Laakkonen P, Krieger S, Mechtler K, Uchida S, Geleff S, Kang DH, Johnson RJ, Kerjaschki D: Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. J Am Soc Nephrol 2003; 14:1981-1989. (Pubitemid 36909905)
18. Kang DH, Joly AH, Oh SW, Hugo C, Kerjaschki D, Gordon KL, Mazzali M, Jefferson JA, Hughes J, Madsen KM, Schreiner GF, Johnson RJ: Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1. J Am Soc Nephrol 2001; 12:1434-1447. (Pubitemid 32666326)
19. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Böhm M, Nickenig G: Circulating endothelial progenitors cells and cardiovascular outcomes. N Engl J Med 2005;353:999-1007. (Pubitemid 41262334)
20. Rosenzweig A: Circulating endothelial progenitors cells as biomarkers. N Engl J Med 2005;353:1055-1057. (Pubitemid 41262341)
21. Yu Y, Fukuda N, Yao EH, Matsumoto T, Kobayashi N, Suzuki R, Tahira Y, Ueno T, Matsumoto K: Effect of an ARB on endothelial progenitor cell function and cardiovascular oxidation in hypertension. Am J Hypertens 2008;21:72-77.
22. Rafii S, Lyden D: Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 2003;9: 702-712. (Pubitemid 36749219)
23. Kelly DJ, Hepper C, Wu LL, Cox AJ, Gilbert RE: Vascular endothelial growth factor expression and glomerular endothelial cell loss in the remnant kidney model. Nephrol Dial Transplant 2003; 18:1286-1292. (Pubitemid 36826947)
24. Spyridopoulos I, Brogi E, Kearney M, Sullivan AB, Cetrulo C, Isner JM, Losordo DW: Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-alpha: balance between growth and death signals. J Mol Cell Cardiol 1997;29:1321-1330. (Pubitemid 27259646)
25. Masuda Y, Shimizu A, Mori T, Ishiwata T, Kitamura H, Ohashi R, Ishizaki M, Asano G, Sugisaki Y, Yamanaka N: Vascular endothelial growth factor enhances glomerular capillary capillary repair and accelerates resolution of experimentally induced glomerulonephritis. Am J Pathol 2001;159:599-608. (Pubitemid 32751090)
26. Aicher A, Zeiher AM, Dimmeier S: Mobilizing endothelial progenitor cells. Hypertension 2005;45:321-325. (Pubitemid 40315795)
27. Sun J, Hopkins BD, Tsujikawa K, Perruzzi C, Adini I, Swerlick R, Bornstein P, Lawler J, Benjamin LE: Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina. Am J Physiol Heart Circ Physiol 2009; 296:H1344-H1351.
28. Mirochnik Y, Kwiatek A, Volpert OV: Thrombospondin and apoptosis: molecular mechanisms and use for design of complementation treatments. Curr Drug Targets 2008;9:851-862.
29. Hugo C, Shankland SJ, Pichler RH, Couser WG, Johnson RJ: Thrombospondin 1, a TGF-β activating protein, precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease. Kidney Int 1998;53:302-311. (Pubitemid 28097847)