Interleukin-6, but Not Soluble Adhesion Molecules, Predicts a Subsequent Mortality from Cardiovascular Disease in Patients with Acute ST-Segment Elevation Myocardial Infarction

Cell Biochemistry and Biophysics

Volumn 61, Issue 2, 2011, Pages 443-448

  Fan, Zhen Xing ^a   Hua, Qi ^a   Li, Yin Ping ^a   Liu, Rong Kun ^a   Yang, Zheng ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Acute ST segment elevation myocardial infarction; Cardiovascular mortality; Interleukin 6; Soluble intercellular adhesion molecule 1; Soluble P selectin; Soluble vascular cell adhesion molecule 1

Indexed keywords

BIOLOGICAL MARKER; CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; PADGEM PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BLOOD; CHEMISTRY; FEMALE; FOLLOW UP; HEART INFARCTION; HUMAN; INFLAMMATION; MALE; MIDDLE AGED; MORTALITY; PROGNOSIS; SOLUBILITY;

BIOLOGICAL MARKERS; CELL ADHESION MOLECULES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; P-SELECTIN; PROGNOSIS; SOLUBILITY; VASCULAR CELL ADHESION MOLECULE-1;

EID: 80955133950     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-011-9209-1     Document Type: Article

References (25)

1. Ross, R. (1999). Atherosclerosis-An inflammatory disease. New England Journal of Medicine, 340, 115-126.
2. Libby, P. (2002). Inflammation in atherosclerosis. Nature, 420, 868-874.
3. Yudkin, J. S., Kumari, M., Humphries, S. E., & Mohamed-Ali, V. (2000). Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link? Atherosclerosis, 148, 209-214.
4. Lindmark, E., Diderholm, E., Wallentin, L., & Siegbahn, A. (2001). Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease: effects of an early invasive or noninvasive strategy. JAMA, 286, 2107-2113.
5. Fisman, E. Z., Benderly, M., Esper, R. J., Behar, S., Boyko, V., Adler, Y., et al. (2006). Interleukin-6 and the risk of future cardiovascular events in patients with angina pectoris and/or healed myocardial infarction. American Journal of Cardiology, 98, 14-18.
6. Blankenberg, S., Rupprecht, H. J., Bickel, C., Peetz, D., Hafner, G., Tiret, L., et al. (2001). Circulating cell adhesion molecules and death in patients with coronary artery disease. Circulation, 104, 1336-1342.
7. Rallidis, L. S., Gika, H. I., Zolindaki, M. G., Xydas, T. A., Paravolidakis, K. E., & Velissaridou, A. H. (2003). Usefulness of elevated levels of soluble vascular cell adhesion molecule-1 in predicting in-hospital prognosis in patients with unstable angina pectoris. American Journal of Cardiology, 92, 1195-1197.
8. Doo, Y. C., Han, S. J., Park, W. J., Kim, S. M., Choi, S. H., Cho, G. Y., et al. (2005). Associations between C-reactive protein and circulating cell adhesion molecules in patients with unstable angina undergoing coronary intervention and their clinical implication. Clinical Cardiology, 28, 47-51.
9. Hillis, G. S., Terregino, C., Taggart, P., Killian, A., Zhao, N., Kaplan, J., et al. (2001). Soluble intercellular adhesion molecule-1 as a predictor of early adverse events in patients with chest pain compatible with myocardial ischemia. Annals of Emergency Medicine, 38, 223-228.
10. Alpert, J. S., Thygesen, K., Antman, E., & Bassand, J. P. (2000). Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. Journal of the American College of Cardiology, 36, 959-969.
11. Killip, T., III, & Kimball, J. T. (1967). Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. American Journal of Cardiology, 20, 457-464.
12. Nakashima, Y., Raines, E. W., Plump, A. S., Breslow, J. L., & Ross, R. (1998). Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arteriosclerosis, Thrombosis, and Vascular Biology, 18, 842-851.
13. Blankenberg, S., Barbaux, S., & Tiret, L. (2003). Adhesion molecules and atherosclerosis. Atherosclerosis, 170, 191-203.
14. Postadzhiyan, A. S., Tzontcheva, A. V., Kehayov, I., & Finkov, B. (2008). Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and their association with clinical outcome, troponin T and C-reactive protein in patients with acute coronary syndromes. Clinical Biochemistry, 41, 126-133.
15. Mulvihill, N. T., Foley, J. B., Murphy, R. T., Curtin, R., Crean, P. A., & Walsh, M. (2001). Risk stratification in unstable angina and non-Q wave myocardial infarction using soluble cell adhesion molecules. Heart, 85, 623-627.
16. Hillis, G. S., Terregino, C., Taggart, P., Killian, A., Zhao, N., Dalsey, W. C., et al. (2002). Elevated soluble P-selectin levels are associated with an increased risk of early adverse events in patients with presumed myocardial ischemia. American Heart Journal, 143, 235-241.
17. Ferroni, P., Rosa, A., Di, F. M., Palmirotta, R., Guadagni, F., Davi, G., et al. (2007). Prognostic significance of interleukin-6 measurement in the diagnosis of acute myocardial infarction in emergency department. Clinica Chimica Acta, 381, 151-156.
18. van der Poll, T., Levi, M., Hack, C. E., Ten, C. H., van Deventer, S. J., Eerenberg, A. J., et al. (1994). Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees. Journal of Experimental Medicine, 179, 1253-1259.
19. Hardardottir, I., Grunfeld, C., & Feingold, K. R. (1994). Effects of endotoxin and cytokines on lipid metabolism. Current Opinion in Lipidology, 5, 207-215.
20. Mastorakos, G., Chrousos, G. P., & Weber, J. S. (1993). Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans. Journal of Clinical Endocrinology and Metabolism, 77, 1690-1694.
21. Ridker, P. M., Rifai, N., Stampfer, M. J., & Hennekens, C. H. (2000). Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation, 101, 1767-1772.
22. Koukkunen, H., Penttila, K., Kemppainen, A., Halinen, M., Penttila, I., Rantanen, T., et al. (2001). C-reactive protein, fibrinogen, interleukin-6 and tumour necrosis factor-alpha in the prognostic classification of unstable angina pectoris. Annals of Medicine, 33, 37-47.
23. Ohtsuka, T., Hamada, M., Inoue, K., Ohshima, K., Sujzuki, J., Matsunaka, T., et al. (2004). Relation of circulating interleukin-6 to left ventricular remodeling in patients with reperfused anterior myocardial infarction. Clinical Cardiology, 27, 417-420.
24. Funayama, H., Ishikawa, S. E., Kubo, N., Yasu, T., Saito, M., & Kawakami, M. (2006). Close association of regional interleukin-6 levels in the infarct-related culprit coronary artery with restenosis in acute myocardial infarction. Circulation Journal, 70, 426-429. 2006.
25. Sukhija, R., Fahdi, I., Garza, L., Fink, L., Scott, M., Aude, W., et al. (2007). Inflammatory markers, angiographic severity of coronary artery disease, and patient outcome. American Journal of Cardiology, 99, 879-884.