Learning impairment by Δ9-tetrahydrocannabinol in adolescence is attributable to deficits in chunking

Behavioural Pharmacology

Volumn 22, Issue 8, 2011, Pages 837-846

  Steel, Ryan W J ^a   Miller, John H ^a   Sim, Dalice A ^a   Day, Darren John ^a  

^a VICTORIA UNIVERSITY OF WELLINGTON   (New Zealand)

Author keywords

adolescence; chunking; D9 tetrahydrocannabinol; postacute; radial maze; rat; reference memory; spatial learning; working memory

Indexed keywords

DRONABINOL;

ADOLESCENT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; LEARNING; LEARNING DISORDER; MALE; NONHUMAN; RAT; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

ANIMALS; BEHAVIOR, ANIMAL; MALE; MAZE LEARNING; MEMORY; RATS; RATS, SPRAGUE-DAWLEY; SPATIAL BEHAVIOR; TETRAHYDROCANNABINOL;

EID: 80855144780     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32834dbbb1     Document Type: Article

References (43)

1. Aceto MD, Scates SM, Lowe JA, Martin BR (1996). Dependence on delta(9)-tetrahydrocannabinol: studies on precipitated and abrupt withdrawal. J Pharmacol Expe Ther 278:1290-1295. (Pubitemid 27166981)
2. Adriani W, Laviola G (2004). Windows of vulnerability to psychopathology and therapeutic strategy in the adolescent rodent model. Behav Pharmacol 15:341-352. (Pubitemid 39238344)
3. Barna I, Soproni K, Arszovszki A, Csabai K, Haller J (2007). WIN-55,212-2 chronically implanted into the CA3 region of the dorsal hippocampus impairs learning: a novel method for studying chronic, brain-area-specific effects of cannabinoids. Behav Pharmacol 18:515-520. (Pubitemid 47356378)
4. Brown MF, Terrinoni M (1996). Control of choice by the spatial configuration of goals. J Exp Psychol-Anim Behav Processes 22:438-446.
5. Brown MF, Giumetti GW (2006). Spatial pattern learning in the radial arm maze. Learn Behav 34:102-108. (Pubitemid 44517632)
6. Cha YM, White AM, Kuhn CM, Wilson WA, Swartzwelder HS (2006). Differential effects of delta(9)-THC on learning in adolescent and adult rats. Pharmacol Biochem Behav 83:448-455. (Pubitemid 43736959)
7. Cha YM, Jones KH, Kuhn CM, Wilson WA, Swartzwelder HS (2007). Sex differences in the effects of delta(9)-tetrahydrocannabinol on spatial learning in adolescent and adult rats. Behav Pharmacol 18:563-569. (Pubitemid 47356382)
8. Cohen JS, Mallet PE, Omalley K (1993). Chunking by proximal arm cues facilitates rats performance in the radial maze. Learning and Motivation 24:413-432.
9. Cohen J, Pardy S, Solway H, Graham H (2003). Chunking versus foraging search patterns by rats in the hierarchically baited radial maze. Anim Cogn 6:93-104. (Pubitemid 38284603)
10. Da Silva GE, Takahashi RN (2002). SR 141716A prevents Delta(9)-tetrahy-drocannabinol-induced spatial learning deficit in a Morris-type water maze in mice. Prog Neuropsychopharmacol Biol Psychiatry 26:321-325. (Pubitemid 34038061)
11. Dallal NL, Meck WH (1990). Hierarchical structures-chunking by food type facilitates spatial memory. J Exp Psychol-Anim Behav Processes 16:69-84.
12. De Lillo C (2004). Imposing structure on a Corsi-type task: evidence for hierarchical organisation based on spatial proximity in serial-spatial memory. Brain Cogn 55:415-426. (Pubitemid 38829607)
13. Dubreuil D, Tixier C, Dutrieux G, Edeline JM (2003). Does the radial arm maze necessarily test spatial memory? Neurobio Learn Mem 79:109-117. (Pubitemid 36071196)
14. Fergusson DM, Boden JM (2008). Cannabis use and later life outcomes. Addiction 103:969-976. (Pubitemid 351703484)
15. Harvey MA, Sellman JD, Porter RJ, Frampton CM (2007). The relationship between non-acute adolescent cannabis use and cognition. Drug Alcohol Rev 26:309-319.
16. Hodges H (1996). Maze procedures: the radial-arm and water maze compared. Cogn Brain Res 3:167-181. (Pubitemid 26198350)
17. Iversen L (2003). Cannabis and the brain. Brain 126:1252-1270. (Pubitemid 36644373)
18. Lichtman AH (2000). SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats. Eur J Pharmacol 404:175-179.
19. Lichtman AH, Martin BR (1996). Delta(9)-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacol 126:125-131. (Pubitemid 26246762)
20. Lichtman AH, Dimen KR, Martin BR (1995). Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacol 119:282-290.
21. Macuda T, Roberts WA (1995). Further evidence for hierarchical chunking in rat spatial memory. J Exp Psychol-Anim Behav Processes 21:20-32.
22. Miller GA (1956). The magical number 7, plus or minus 2-some limits on our capacity for processing information. Psychol Rev 63:81-97.
23. Mishima K, Egashira N, Hirosawa N, Fujii M, Matsumoto Y, Iwasaki K, Fujiwara M (2001). Characteristics of learning and memory impairment induced by delta(9)-tetrahydrocannabinol in rats. Jpn J Pharmacol 87:297-308.
24. Moore NLT, Greenleaf ALR, Acheson SK, Wilson WA, Swartzwelder HS, Kuhn CM (2010). Role of cannabinoid receptor type 1 desensitization in greater tetrahydrocannabinol impairment of memory in adolescent rats. J Pharmacol Exp Ther 335:294-301.
25. Murray RM, Morrison PD, Henquet C, Di Forti M (2007). Science and society-Cannabis, the mind and society: the hash realities. Nat Rev Neurosci 8:885-895. (Pubitemid 350006219)
26. Nakamura EM, Dasilva EA, Concilio GV, Wilkinson DA, Masur J (1991). Reversible effects of acute and long-term administration of delta-9- tetrahydrocannabinol (THC) on memory in the rat. Drug and Alcohol Depend 28:167-175.
27. Nelson C, Bawa J, Finger S (1992). Radial maze performance after hippocampal-lesions-beneficial-effects of nimodipine. Restor Neurol Neurosci 4:33-40.
28. O'Shea M, Singh ME, McGregor IS, Mallet PE (2004). Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats. J Psychopharmacol 18:502-508. (Pubitemid 39665118)
29. Olton DS, Collison C, Werz MA (1977). Spatial memory and radial arm maze performance of rats. Learn Motiv 8:289-314.
30. Olton DS, Papas BC (1979). Spatial memory and hippocampal function. Neuropsychologia 17:669-682. (Pubitemid 10167907)
31. Olton DS, Samuelson RJ (1976). Remembrance of places passed-spatial memory in rats. J Exp Psychol-Anim Behav Processes 2:97-116.
32. Quinn HR, Matsumoto I, Callaghan PD, Long LE, Arnold JC, Gunasekaran N, et al. (2008). Adolescent rats find repeated delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacol 33:1113-1126. (Pubitemid 351367534)
33. Richmond MA, Yee BK, Pouzet B, Veenman L, Rawlins JNP, Feldon J, Bannerman DM (1999). Dissociating context and space within the hippocampus: effects of complete, dorsal and ventral excitotoxic hippocampal lesions on conditioned freezing and spatial learning. Behav Neurosci 113:1189-1203. (Pubitemid 30013826)
34. Ridgeway D (2006). Strategic grouping in the spatial span memory task. Memory 14:990-1000. (Pubitemid 44688011)
35. Rubino T, Vigano D, Realini N, Guidali C, Braida D, Capurro V, et al. (2008). Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. Neuropsychopharmacol 33:2760-2771.
36. Rubino T, Realini N, Braida D, Alberio T, Capurro V, Virgano D, et al. (2009). The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortex. Neurotoxicity Res 15:291-302.
37. Sakai K, Kitaguchi K, Hikosaka O (2003). Chunking during human visuomotor sequence learning. Exp Brain Res 152:229-242. (Pubitemid 37153644)
38. Schneider M, Koch M (2003). Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory and the performance in a progressive ratio task in adult rats. Neuropsycho-pharmacol 28:1760-1769. (Pubitemid 41070841)
39. Spear LP (2000). The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24:417-463. (Pubitemid 30243061)
40. Talpos JC, Dias R, Bussey TJ, Saksida LM (2008). Hippocampal lesions in rats impair learning and memory for locations on a touch-sensitive computer screen: the 'ASAT' task. Behav Brain Res 192:216-225.
41. Terrace HS (1987). Chunking by a pigeon in a serial-learning task. Nat 325: 149-151.
42. Ward MT, Stoelzel CR, Markus EJ (1999). Hippocampal dysfunction during aging II: deficits on the radial-arm maze. Neurobiol Aging 20:373-380.
43. Wise LE, Iredale PA, Lichtman AH (2008). The cannabinoid CB1 receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task. Eur J Pharmacol 590:246-249.