Melatonin ameliorates necrotizing enterocolitis in a neonatal rat model

Journal of Pediatric Surgery

Volumn 46, Issue 11, 2011, Pages 2101-2107

  Guven, Ahmet ^a   Uysal, Bulent ^a   Gundogdu, Gokhan ^a   Oztas, Emin ^a   Ozturk, Haluk ^a   Korkmaz, Ahmet ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Melatonin; Necrotizing enterocolitis; Oxidant Antioxidant system

Indexed keywords

GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; MALONALDEHYDE; MELATONIN; NITRATE; NITRITE; OXYGEN; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; COLD STRESS; CONTROLLED STUDY; DRUG EFFICACY; ENTERIC FEEDING; HISTOPATHOLOGY; HYPOXIA; MORTALITY; NECROTIZING ENTEROCOLITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN CONTENT; RAT; TREATMENT OUTCOME; WEIGHT REDUCTION;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; ANTIOXIDANTS; COLD TEMPERATURE; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENTERAL NUTRITION; ENTEROCOLITIS, NECROTIZING; GLUTATHIONE PEROXIDASE; ILEUM; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; MELATONIN; NITRATES; NITRITES; OXIDATIVE STRESS; OXYGEN INHALATION THERAPY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; WEIGHT LOSS;

EID: 80855136437     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2011.06.040     Document Type: Article

References (50)

1. P.W. Lin, and B.J. Stoll Necrotising enterocolitis Lancet 368 2006 1271 1283
2. M.C. Henry, and R.L. Moss Neonatal necrotizing enterocolitis Semin Pediatr Surg 17 2008 98 109
3. K. Gibbs, J. Lin, and I.R. Holzman Necrotising enterocolitis: the state of the science Indian J Pediatr 74 2007 67 72
4. W. Hsueh, M.S. Caplan, and X.W. Qu Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic concepts Pediatr Dev Pathol 6 2003 6 23
5. T. Jilling, D. Simon, and J. Lu The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis J Immunol 177 2006 3273 3282
6. Y. Ito, S.M. Doelle, and J.A. Clark Intestinal microcirculatory dysfunction during the development of experimental necrotizing enterocolitis Pediatr Res 61 2007 180 184
7. M.S. Caplan, D. Simon, and T. Jilling The role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitis Semin Pediatr Surg 14 2005 145 151
8. R. Zamora, N.S. Bryan, and P. Boyle Nitrosative stress in an animal model of necrotizing enterocolitis Free Radic Biol Med 39 2005 1428 1437
9. E.P. Nadler, E. Dickinson, and A. Knisely Expression of inducible nitric oxide synthase and interleukin-12 in experimental necrotizing enterocolitis J Surg Res 92 2000 71 77
10. K.L. Schnabl, J.E. Van Aerde, and A.B. Thomson Necrotizing enterocolitis: a multifactorial disease with no cure World J Gastroenterol 14 2008 2142 2161
11. M. Kul, S. Vurucu, and E. Demirkaya Enteral glutamine and/or arginine supplementation have favorable effects on oxidative stress parameters in neonatal rat intestine J Pediatr Gastroenterol Nutr 49 2009 85 89
12. A. Sizlan, A. Guven, and B. Uysal Proanthocyanidin protects intestine and remote organs against mesenteric ischemia/reperfusion injury World J Surg 33 2009 1384 1391
13. A. Guven, G. Gundogdu, and S. Vurucu Medical ozone therapy reduces oxidative stress and intestinal damage in an experimental model of necrotizing enterocolitis in neonatal rats J Pediatr Surg 44 2009 1730 1735
14. J. Travadi, S. Patole, and A. Charles Pentoxifylline reduces the incidence and severity of necrotizing enterocolitis in a neonatal rat model Pediatr Res 60 2006 185 189
15. F.O. Cadir, U. Bicakci, and B. Tander Protective effects of vitamin E and omeprazole on the hypoxia/reoxygenation induced intestinal injury in newborn rats Pediatr Surg Int 24 2008 809 813
16. P.J. Thor, G. Krolczyk, and K. Gil Melatonin and serotonin effects on gastrointestinal motility J Physiol Pharmacol 58 Suppl 6 2007 97 103
17. G.A. Bubenik Gastrointestinal melatonin: localization, function, and clinical relevance Dig Dis Sci 47 2002 2336 2348
18. E. Gitto, S. Pellegrino, and P. Gitto Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin J Pineal Res 46 2009 128 139
19. V. Kesik, A. Guven, and S. Vurucu Melatonin and 1400 W ameliorate both intestinal and remote organ injury following mesenteric ischemia/reperfusion J Surg Res 157 2009 e97 e105
20. R. Hardeland, D.X. Tan, and R.J. Reiter Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines J Pineal Res 47 2009 109 126
21. A. Zani, L. Cordischi, and M. Cananzi Assessment of a neonatal rat model of necrotizing enterocolitis Eur J Pediatr Surg 18 2008 423 426
22. O.H. Lowry, N.J. Rosebrough, and A.L. Farr Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
23. H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 1979 351 358
24. R.L. Levine, D. Garland, and C.N. Oliver Determination of carbonyl content in oxidatively modified proteins Methods Enzymol 186 1990 464 478
25. Y. Sun, L.W. Oberley, and Y. Li A simple method for clinical assay of superoxide dismutase Clin Chem 34 1988 497 500
26. D.E. Paglia, and W.N. Valentine Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J Lab Clin Med 70 1967 158 169
27. K.M. Miranda, M.G. Espey, and D.A. Wink A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite Nitric Oxide 5 2001 62 71
28. A. Guven, G. Gundogdu, and B. Uysal Hyperbaric oxygen therapy reduces the severity of necrotizing enterocolitis in a neonatal rat model J Pediatr Surg 44 2009 534 540
29. T. Jilling, J. Lu, and M. Jackson Intestinal epithelial apoptosis initiates gross bowel necrosis in an experimental rat model of neonatal necrotizing enterocolitis Pediatr Res 55 2004 622 629
30. H. Ford, S. Watkins, and K. Reblock The role of inflammatory cytokines and nitric oxide in the pathogenesis of necrotizing enterocolitis J Pediatr Surg 32 1997 275 282
31. J.P. Cueva, and W. Hsueh Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis Gut 29 1988 1207 1212
32. H. Ceylan, M. Yuncu, and A. Gurel Effects of whole-body hypoxic preconditioning on hypoxia/reoxygenation-induced intestinal injury in newborn rats Eur J Pediatr Surg 15 2005 325 332
33. P.T. Sangild, R.H. Siggers, and M. Schmidt Diet- and colonization- dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs Gastroenterology 130 2006 1776 1792
34. J.S. Lee, and R.A. Polin Treatment and prevention of necrotizing enterocolitis Semin Neonatol 8 2003 449 459
35. S. Uguralp, B. Mizrak, and A.B. Karabulut Interferon-alpha reduces the development of experimental necrotizing enterocolitis Cytokine 25 2004 204 211
36. M.J. Miller, H. McNeill, and K.M. Mullane SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis Am J Physiol 255 1988 G556 565
37. R.J. Reiter, F. Gultekin, and L.J. Flores Melatonin: potential utility for improving public health TAF Prev Med Bull 5 2006 131 158
38. M. Allegra, R.J. Reiter, and D.X. Tan The chemistry of melatonin's interaction with reactive species J Pineal Res 34 2003 1 10
39. C. Rodriguez, J.C. Mayo, and R.M. Sainz Regulation of antioxidant enzymes: a significant role for melatonin J Pineal Res 36 2004 1 9
40. D.X. Tan, L.C. Manchester, and M.P. Terron One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 42 2007 28 42
41. O. Ergun, G. Ergun, and G. Oktem Enteral resveratrol supplementation attenuates intestinal epithelial inducible nitric oxide synthase activity and mucosal damage in experimental necrotizing enterocolitis J Pediatr Surg 42 2007 1687 1694
42. M.B. Edelson, C.E. Bagwell, and H.J. Rozycki Circulating pro- and counterinflammatory cytokine levels and severity in necrotizing enterocolitis Pediatrics 103 1999 766 771
43. Paradies G, Petrosillo G, Paradies V, et al. Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res 48:297-310.
44. N. Ersoz, M. Ozler, and O. Altinel Melatonin prevents peritoneal adhesions in rats J Gastroenterol Hepatol 24 2009 1763 1767
45. S.H. Kim, and S.M. Lee Cytoprotective effects of melatonin against necrosis and apoptosis induced by ischemia/reperfusion injury in rat liver J Pineal Res 44 2008 165 171
46. S. Cuzzocrea, G. Costantino, and E. Gitto Protective effects of melatonin in ischemic brain injury J Pineal Res 29 2000 217 227
47. F. Fulia, E. Gitto, and S. Cuzzocrea Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin J Pineal Res 31 2001 343 349
48. E. Gitto, M. Karbownik, and R.J. Reiter Effects of melatonin treatment in septic newborns Pediatr Res 50 2001 756 760
49. E. Gitto, R.J. Reiter, and S.P. Cordaro Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin Am J Perinatol 21 2004 209 216
50. A. Korkmaz, R.J. Reiter, and T. Topal Melatonin: an established antioxidant worthy of use in clinical trials Mol Med 15 2009 43 50