Total lymphoid irradiation in heart transplantation: Long-term efficacy and survival-an 18-year experience

Transplantation

Volumn 92, Issue 10, 2011, Pages 1159-1164

  Tallaj, José A ^a,b   Pamboukian, Salpy V ^a   George, James F ^c   Brown, Robert N ^c   Pajaro, Octavio E ^c   Bourge, Robert C ^a   Cadeiras, Martin ^a   Smallfield, Melissa ^a   Kirklin, James K ^c   McGiffin, David C ^c  

^a University of Alabama at Birmingham   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

^c Kentucky   (United States)

Author keywords

Heart transplantation; Outcomes; Total lymphoid irradiation

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE MEGAKARYOCYTIC LEUKEMIA; ADULT; ARTICLE; CARDIAC ALLOGRAFT VASCULOPATHY; CARDIAC GRAFT REJECTION; COHORT ANALYSIS; FOLLOW UP; GRAFT INFECTION; GRAFT SURVIVAL; HEART HEMODYNAMICS; HEART TRANSPLANTATION; HUMAN; LYMPH NODE IRRADIATION; MAJOR CLINICAL STUDY; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; RADIATION DOSE; RISK ASSESSMENT; TREATMENT OUTCOME; VASCULITIS;

ADULT; GRAFT REJECTION; HEART TRANSPLANTATION; HEMODYNAMICS; HUMANS; LYMPHATIC IRRADIATION; PARAPROTEINEMIAS;

EID: 80855131621     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e318231e9d3     Document Type: Article

References (30)

1. Kaplan HS, Rosenberg SA. Extended-field radical radiotherapy in advanced Hodgkin's disease: Short-term results of 2 randomized clinical trials. Cancer Res 1966; 26: 1268.
2. Fuks Z, Strober S, Bobrove AM, et al. Long term effects of radiation on T and B lymphocytes in peripheral blood of patients with Hodgkin's disease. J Clin Invest 1976; 58: 803.
3. Kirklin JK, Naftel DC, McGiffin DC, et al. Analysis of morbid events and risk factors for death after cardiac transplantation. J Am Coll Cardiol 1988; 11: 917.
4. Villar RC, Chocair PR, Nadalin W, et al. Total lymphoid irradiation for pretransplant immunosuppression and recurrence of focal segmental glomerulosclerosis. Transpl Int 2008; 21: 286.
5. Lim TS, O'Driscoll G, Freund J, et al. Short-course total lymphoid irradiation for refractory cardiac transplantation rejection. J Heart Lung Transplant 2007; 26: 1249.
6. Trivedi HL, Kaneku H, Terasaki PI, et al. Clonal deletion using total lymphoid irradiation with no maintenance immunosuppression in renal allograft recipients. Clin Transpl 2009: 265.
7. Bhorade SM, Stern E. Immunosuppression for lung transplantation. Proc Am Thorac Soc 2009; 6: 47.
8. Verleden GM, Lievens Y, Dupont LJ, et al. Efficacy of total lymphoid irradiation in azithromycin nonresponsive chronic allograft rejection after lung transplantation. Transplant Proc 2009; 41: 1816.
9. Comerci GD Jr, Williams TM, Kellie S. Immune tolerance after total lymphoid irradiation for heart transplantation: Immunosuppressantfree survival for 8 years. J Heart Lung Transplant 2009; 28: 743.
10. Neurohr C, Behr J. [Immunosuppression and infection prophylaxis after lung transplantation.] Pneumologie 2011; 65: 94.
11. Ghadjar P, Joos D, Martinelli M, et al. Tailored total lymphoid irradiation in heart transplant patients: 10-years experience of one center. Radiat Oncol 2010; 5: 3.
12. Chin C, Hunt S, Robbins R, et al. Long-term follow-up after total lymphoid irradiation in pediatric heart transplant recipients. J Heart Lung Transplant 2002; 21: 667.
13. Kobashigawa J, Crespo-Leiro MG, Ensminger SM, et al. Report from a consensus conference on antibody-mediated rejection in heart transplantation. J Heart Lung Transplant 2011; 30: 252.
14. Kirklin JK, Naftel DC, Kirklin JW, et al. Risk factors for death and related events after cardiac transplantation. Adv Cardiol 1988; 36: 278.
15. Blackstone EH, Naftel DC, Turner ME. The decomposition of timevarying hazard into phases, each incorporating a separate stream of concomitant information. J Am Stat Assoc 1986; 81: 615.
16. Chin C, Naftel DC, Singh TP, et al. Risk factors for recurrent rejection in pediatric heart transplantation: A multicenter experience. J Heart Lung Transplant 2004; 23: 178.
17. Kirklin JK, Young J, McGiffin DC. Survival after heart transplantation. In: Heart transplantation. New York, Churchill Livingstone 2003, p 587.
18. Rigby SM, Rouse T, Field EH. Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4-producing CD4-TNK cells and skews differentiation of immunocompetent donor CD4cells. Blood 2003; 101: 2024.
19. Evans MA, Schomberg PJ, Rodeheffer RJ, et al. Total lymphoid irradiation: A novel and successful therapy for resistant cardiac allograft rejection. Mayo Clin Proc 1992; 67: 785.
20. Salter MM, Kirklin JK, Bourge RC, et al. Total lymphoid irradiation in the treatment of early or recurrent heart rejection. J Heart Lung Transplant 1992; 11: 902.
21. Kirklin JK, George JF, McGiffin DC, et al. Total lymphoid irradiation: Is there a role in pediatric heart transplantation? J Heart Lung Transplant 1993; 12(6 Pt 2): S293.
22. Salter SP, SalterMM,Kirklin JK, et al. Total lymphoid irradiation in the treatment of early or recurrent heart transplant rejection. Int J Radiat Oncol Biol Phys 1995; 33: 83.
23. Krause JR. Morphology and classification of acute myeloid leukemias. Clin Lab Med 2000; 20: 1.
24. George JF, Taylor DO, Blume ED, et al. Minimizing infection and rejection death: Clues acquired from 19 years of multi-institutional cardiac transplantation data. J Heart Lung Transplant 2011; 30: 151.
25. George JF, Pamboukian SV, Tallaj JA, et al. Balancing rejection and infection with respect to age, race, and gender: Clues acquired from 17 years of cardiac transplantation data. J Heart Lung Transplant 2010; 29: 966.
26. Kubo SH, Naftel DC, Mills RM Jr, et al. Risk factors for late recurrent rejection after heart transplantation: A multiinstitutional, multivariable analysis. Cardiac Transplant Research Database Group. J Heart Lung Transplant 1995; 14: 409.
27. Halperin EC, Haas G, Dosoretz DE, et al. 1982 resident's essay award: The immunologic effects of lymphoid irradiation in human and nonhuman primates: Cellular changes and the potential for renal transplantation. Int J Radiat Oncol Biol Phys 1983; 9: 1083.
28. Bourge RC, Naftel DC, Costanzo-Nordin MR, et al. Pretransplantation risk factors for death after heart transplantation: A multiinstitutional study. The Transplant Cardiologists Research Database Group. J Heart Lung Transplant 1993; 12: 549.
29. Mills RM, Naftel DC, Kirklin JK, et al. Heart transplant rejection with hemodynamic compromise: A multiinstitutional study of the role of endomyocardial cellular infiltrate. Cardiac Transplant Research Database. J Heart Lung Transplant 1997; 16: 813.
30. Billingham ME, Cary NR, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. The International Society for Heart Transplantation. J Heart Transplant 1990; 9: 587.