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Volumn 82, Issue 11, 2011, Pages 989-994

Neoadjuvant therapy concepts for liver metastases;Neoadjuvante Therapiekonzepte bei Lebermetastasen

Author keywords

Liver metastases; Neoadjuvant therapy; Remission; Resectability; Systemic therapy

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAMPTOTHECIN; CETUXIMAB; DRUG DERIVATIVE; FLUOROURACIL; FOLINIC ACID; MONOCLONAL ANTIBODY; PLATINUM COMPLEX;

EID: 80855131559     PISSN: 00094722     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00104-011-2131-7     Document Type: Article
Times cited : (7)

References (37)
  • 1
    • 64649092523 scopus 로고    scopus 로고
    • Patients with initially unresectable colorectal liver metastases: Is there a possibility of cure?
    • Adam R, Wicherts DA, Haas RJ de et al (2009) Patients with initially unresectable colorectal liver metastases: is there a possibility of cure? J Clin Oncol 27(11):1829-1835
    • (2009) J Clin Oncol , vol.27 , Issue.11 , pp. 1829-1835
    • Adam, R.1    Wicherts, D.A.2    de Haas, R.J.3
  • 2
    • 80053289906 scopus 로고    scopus 로고
    • Trends in incidence, treatment and survival of patients with stage IV colorectal cancer; a population-based series
    • [Epub ahead of print]
    • Pool AE van der, Damhuis RA, Ijzermans JN et al (2010) Trends in incidence, treatment and survival of patients with stage IV colorectal cancer; a population-based series. Colorectal Dis [Epub ahead of print]
    • (2010) Colorectal Dis
    • van der Pool, A.E.1    Damhuis, R.A.2    Ijzermans, J.N.3
  • 3
    • 68949094312 scopus 로고    scopus 로고
    • Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
    • Kopetz S, Chang GJ, Overman MJ et al (2009) Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 27(22):3677-3683
    • (2009) J Clin Oncol , vol.27 , Issue.22 , pp. 3677-3683
    • Kopetz, S.1    Chang, G.J.2    Overman, M.J.3
  • 4
    • 77953632852 scopus 로고    scopus 로고
    • Surgical management and outcomes of colorectal cancer liver metastases
    • Morris EJ, Forman D, Thomas JD et al (2010) Surgical management and outcomes of colorectal cancer liver metastases. Br J Surg 97(7):1110-1118
    • (2010) Br J Surg , vol.97 , Issue.7 , pp. 1110-1118
    • Morris, E.J.1    Forman, D.2    Thomas, J.D.3
  • 5
    • 0032791959 scopus 로고    scopus 로고
    • Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery
    • Giacchetti S, Itzhaki M, Gruia G et al (1999) Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery. Ann Oncol 10(6):663-669
    • (1999) Ann Oncol , vol.10 , Issue.6 , pp. 663-669
    • Giacchetti, S.1    Itzhaki, M.2    Gruia, G.3
  • 6
    • 33644819672 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: A north central cancer treatment group phase II study
    • Alberts SR, Horvath WL, Sternfeld WC et al (2005) Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a north central cancer treatment group phase II study. J Clin Oncol 23(36):9243-9249
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9243-9249
    • Alberts, S.R.1    Horvath, W.L.2    Sternfeld, W.C.3
  • 7
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates
    • Folprecht G, Grothey A, Alberts S et al (2005) Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann Oncol 16(8):1311-1319
    • (2005) Ann Oncol , vol.16 , Issue.8 , pp. 1311-1319
    • Folprecht, G.1    Grothey, A.2    Alberts, S.3
  • 8
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
    • Souglakos J, Androulakis N, Syrigos K et al (2006) FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 94(6):798-805
    • (2006) Br J Cancer , vol.94 , Issue.6 , pp. 798-805
    • Souglakos, J.1    Androulakis, N.2    Syrigos, K.3
  • 9
    • 34249000361 scopus 로고    scopus 로고
    • Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
    • Falcone A, Ricci S, Brunetti I et al (2007) Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 25(13):1670-1676
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1670-1676
    • Falcone, A.1    Ricci, S.2    Brunetti, I.3
  • 10
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ et al (2008) K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 359(17):1757-1765
    • (2008) N Engl J Med , vol.359 , Issue.17 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 11
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor k-ras and -braf mutation status
    • Van Cutsem E, Köhne CH, Lang I et al (2011) Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor k-ras and -braf mutation status. J Clin Oncol 29(15):2011-2019
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2011-2019
    • van Cutsem, E.1    Köhne, C.H.2    Lang, I.3
  • 12
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
    • Bokemeyer C, Bondarenko I, Hartmann JT et al (2011) Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 22(7):1535-1546
    • (2011) Ann Oncol , vol.22 , Issue.7 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3
  • 13
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomised phase 2 trial
    • Folprecht G, Gruenberger T, Bechstein WO et al (2010) Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 11(1):38-47
    • (2010) Lancet Oncol , vol.11 , Issue.1 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3
  • 14
    • 79959337678 scopus 로고    scopus 로고
    • Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
    • Maughan TS, Adams RA, Smith CG et al (2011) Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet 377(9783):2103-2114
    • (2011) Lancet , vol.377 , Issue.9783 , pp. 2103-2114
    • Maughan, T.S.1    Adams, R.A.2    Smith, C.G.3
  • 15
    • 78149250536 scopus 로고    scopus 로고
    • Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) vs FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
    • Douillard JY, Siena S, Cassidy J et al (2010) Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) vs FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 28(31):4697-4705
    • (2010) J Clin Oncol , vol.28 , Issue.31 , pp. 4697-4705
    • Douillard, J.Y.1    Siena, S.2    Cassidy, J.3
  • 16
    • 79952153189 scopus 로고    scopus 로고
    • Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: The Nordic VII study (Nct00145314), by the Nordic Colorectal Cancer Biomodulation Group
    • Tveit K, Guren T, Glimelius B et al (2010) Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: the Nordic VII study (Nct00145314), by the Nordic Colorectal Cancer Biomodulation Group. Ann Oncol 21:9
    • (2010) Ann Oncol , vol.21 , pp. 9
    • Tveit, K.1    Guren, T.2    Glimelius, B.3
  • 17
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W et al (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350(23):2335-2342
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 18
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • Kabbinavar FF, Hambleton J, Mass RD et al (2005) Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 23(16):3706-3712
    • (2005) J Clin Oncol , vol.23 , Issue.16 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3
  • 19
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz LB, Clarke S, Diaz-Rubio E et al (2008) Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 26(12):2013-2019
    • (2008) J Clin Oncol , vol.26 , Issue.12 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Diaz-Rubio, E.3
  • 20
    • 11144354740 scopus 로고    scopus 로고
    • Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer
    • Rubbia-Brandt L, Audard V, Sartoretti P et al (2004) Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Ann Oncol 15(3):460-466
    • (2004) Ann Oncol , vol.15 , Issue.3 , pp. 460-466
    • Rubbia-Brandt, L.1    Audard, V.2    Sartoretti, P.3
  • 21
    • 33646457231 scopus 로고    scopus 로고
    • Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases
    • Vauthey JN, Pawlik TM, Ribero D et al (2006) Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol 24(13):2065-2072
    • (2006) J Clin Oncol , vol.24 , Issue.13 , pp. 2065-2072
    • Vauthey, J.N.1    Pawlik, T.M.2    Ribero, D.3
  • 22
    • 37549068554 scopus 로고    scopus 로고
    • Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy
    • Nakano H, Oussoultzoglou E, Rosso E et al (2008) Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy. Ann Surg 247(1):118-124
    • (2008) Ann Surg , vol.247 , Issue.1 , pp. 118-124
    • Nakano, H.1    Oussoultzoglou, E.2    Rosso, E.3
  • 23
    • 40749149728 scopus 로고    scopus 로고
    • Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): A randomised controlled trial
    • Nordlinger B, Sorbye H, Glimelius B et al (2008) Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 371(9617):1007-1016
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 1007-1016
    • Nordlinger, B.1    Sorbye, H.2    Glimelius, B.3
  • 24
    • 30144435398 scopus 로고    scopus 로고
    • Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases
    • Karoui M, Penna C, Amin-Hashem M et al (2006) Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases. Ann Surg 243(1):1-7
    • (2006) Ann Surg , vol.243 , Issue.1 , pp. 1-7
    • Karoui, M.1    Penna, C.2    Amin-Hashem, M.3
  • 25
    • 24344442899 scopus 로고    scopus 로고
    • Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab
    • Scappaticci FA, Fehrenbacher L, Cartwright T et al (2005) Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 91(3):173-180
    • (2005) J Surg Oncol , vol.91 , Issue.3 , pp. 173-180
    • Scappaticci, F.A.1    Fehrenbacher, L.2    Cartwright, T.3
  • 26
    • 79251504595 scopus 로고    scopus 로고
    • Impact of bevacizumab on functional recovery and histology of the liver after resection of colorectal metastases
    • Wicherts DA, Haas RJ de, Sebagh M et al (2011) Impact of bevacizumab on functional recovery and histology of the liver after resection of colorectal metastases. Br J Surg 98(3):399-407
    • (2011) Br J Surg , vol.98 , Issue.3 , pp. 399-407
    • Wicherts, D.A.1    de Haas, R.J.2    Sebagh, M.3
  • 27
    • 42949130734 scopus 로고    scopus 로고
    • Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer
    • Gruenberger B, Tamandl D, Schueller J et al (2008) Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer. J Clin Oncol 26(11):1830-1835
    • (2008) J Clin Oncol , vol.26 , Issue.11 , pp. 1830-1835
    • Gruenberger, B.1    Tamandl, D.2    Schueller, J.3
  • 28
    • 54449087716 scopus 로고    scopus 로고
    • Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: A pooled analysis of two randomized trials
    • Mitry E, Fields AL, Bleiberg H et al (2008) Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials. J Clin Oncol 26(30):4906-4911
    • (2008) J Clin Oncol , vol.26 , Issue.30 , pp. 4906-4911
    • Mitry, E.1    Fields, A.L.2    Bleiberg, H.3
  • 29
    • 77953662328 scopus 로고    scopus 로고
    • Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials
    • Wieser M, Sauerland S, Arnold D et al (2010) Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: a systematic review and meta-analysis of randomized trials. BMC Cancer 10:309
    • (2010) BMC Cancer , vol.10 , pp. 309
    • Wieser, M.1    Sauerland, S.2    Arnold, D.3
  • 30
    • 33748460684 scopus 로고    scopus 로고
    • Complete response of colorectal liver metastases after chemotherapy: Does it mean cure?
    • Benoist S, Brouquet A, Penna C et al (2006) Complete response of colorectal liver metastases after chemotherapy: does it mean cure? J Clin Oncol 24(24):3939-3945
    • (2006) J Clin Oncol , vol.24 , Issue.24 , pp. 3939-3945
    • Benoist, S.1    Brouquet, A.2    Penna, C.3
  • 31
    • 79959491382 scopus 로고    scopus 로고
    • Patients operated on for initially unresectable colorectal liver metastases with missing metastases experience a favorable long-term outcome
    • Goere D, Gaujoux S, Deschamp F et al (2011) Patients operated on for initially unresectable colorectal liver metastases with missing metastases experience a favorable long-term outcome. Ann Surg 254(1):114-118
    • (2011) Ann Surg , vol.254 , Issue.1 , pp. 114-118
    • Goere, D.1    Gaujoux, S.2    Deschamp, F.3
  • 32
    • 77949402976 scopus 로고    scopus 로고
    • Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy
    • Auer RC, White RR, Kemeny NE et al (2010) Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy. Cancer 116(6):1502-1509
    • (2010) Cancer , vol.116 , Issue.6 , pp. 1502-1509
    • Auer, R.C.1    White, R.R.2    Kemeny, N.E.3
  • 33
    • 43249130975 scopus 로고    scopus 로고
    • Complete pathologic response after preoperative chemotherapy for colorectal liver metastases: Myth or reality?
    • Adam R, Wicherts DA, Haas RJ de et al (2008) Complete pathologic response after preoperative chemotherapy for colorectal liver metastases: myth or reality? J Clin Oncol 26(10):1635-1641
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1635-1641
    • Adam, R.1    Wicherts, D.A.2    de Haas, R.J.3
  • 34
    • 56749096759 scopus 로고    scopus 로고
    • Pathologic response to preoperative chemotherapy: A new outcome end point after resection of hepatic colorectal metastases
    • Blazer DG III, Kishi Y, Maru DM et al (2008) Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol 26(33):5344-5351
    • (2008) J Clin Oncol , vol.26 , Issue.33 , pp. 5344-5351
    • Blazer III, D.G.1    Kishi, Y.2    Maru, D.M.3
  • 35
    • 77956189945 scopus 로고    scopus 로고
    • Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: A phase 2 trial
    • Masi G, Loupakis F, Salvatore L et al (2010) Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. Lancet Oncol 11(9):845-852
    • (2010) Lancet Oncol , vol.11 , Issue.9 , pp. 845-852
    • Masi, G.1    Loupakis, F.2    Salvatore, L.3
  • 36
    • 78149469673 scopus 로고    scopus 로고
    • Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial
    • Garufi C, Torsello A, Tumolo S et al (2010) Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial. Br J Cancer 103(10):1542-1547
    • (2010) Br J Cancer , vol.103 , Issue.10 , pp. 1542-1547
    • Garufi, C.1    Torsello, A.2    Tumolo, S.3
  • 37
    • 80855145177 scopus 로고    scopus 로고
    • Cetuximab and FOLFOXIRI: Dose-escalation study in previously untreated patients with metastatic colorectal cancer
    • (Abstract 480), January 22-24, 2010, Orlando, Florida
    • Folprecht G, Schuette K, Stoehlmacher J et al (2010) Cetuximab and FOLFOXIRI: dose-escalation study in previously untreated patients with metastatic colorectal cancer. Proc Gastrointest Canc Symp, January 22-24, 2010, Orlando, Florida (Abstract 480)
    • (2010) Proc Gastrointest Canc Symp
    • Folprecht, G.1    Schuette, K.2    Stoehlmacher, J.3


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