Comparison between nuclear magnetic resonance profiling and the source/sink approach for characterizing drug diffusion in hydrogel matrices

Pharmaceutical Development and Technology

Volumn 16, Issue 6, 2011, Pages 651-656

  Gagnon, Marc André ^a   Lafleur, Michel ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Controlled drug release; Diffusion; Hydrogel; NMR profiling; PFG NMR

Indexed keywords

ALENDRONIC ACID; CURDLAN;

ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; DRUG TRANSPORT; HYDROGEL; INTERMETHOD COMPARISON; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SOURCE SINK RELATIONSHIP; VALIDITY;

ALENDRONATE; BETA-GLUCANS; DELAYED-ACTION PREPARATIONS; DIFFUSION; HYDROGELS; MAGNETIC RESONANCE SPECTROSCOPY; TECHNOLOGY, PHARMACEUTICAL;

EID: 80755181423     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2010.502900     Document Type: Article

References (36)

1. Lin C-C, Metters AT. Hydrogels in controlled release formulations: Network design and mathematical modelings. Adv Drug Deliv Rev 2006;58:1379-1408.
2. Peppas NA, Bures P, Leobandung W, Ichikawa H. Hydro-gels in pharmaceutical formulations. Eur J Pharm Biopharm 2000;50:27-46.
3. Bearman RJ. On the molecular basis of some current theories of difusion. J Phys Chem 1961;65:1961-1968.
4. Crank J. Te mathematics of difusion. 2nd ed. Oxford, UK: Clarendon Press; 1975.
5. Westrin BA, Axelsson A, Zacchi G. Difusion measurement in gels. J Controlled Release 1994;30:189-199.
6. Upadrashta SM, Häglund BO, Sundelöf L-O. Difusion and concentration profles of drugs in gels. J Pharm Sci 1993;82:1094-1098. (Pubitemid 24004438)
7. Labille J, Fatin-Rouge N, Bufe J. Local and average difusion of nanosolutes in agarose gels: Te efect of the gel/solution interface structure. Langmuir 2007;23:2083-2090. (Pubitemid 46406166)
8. Weng L, Lu Y, Shi L, Zhang X, Zhang L, Guo X, et al. In situ investigation of drug difusion in hydrogels by the refractive index method. Anal Chem 2004;76:2807-2812. (Pubitemid 38657706)
9. Dunmire EN, Plenys AM, Katz D F. Spectrophotometric analysis of molecular transport in gels. J Controlled Release 1999;57:127-140. (Pubitemid 29062865)
10. Pearl Z, Magaritz M, Bendel P. Measuring difusion coefcients of solutes in porous media by NMR imaging. J Magn Reson 1991; 95:597-602.
11. Banas K, Brandani F, Ruthven DM, Stallmach F, Kärger J. Combining macroscopic and microscopic difusion studies in zeolites using NMR techniques. Magn Reson Imaging 2005;23:227-232.
12. Balcom BJ, Fischer AE, Carpenter TA, Hall LD. Difusion in aqueous gels. Mutual difusion coefcients measured by one-dimensional nuclear magnetic resonance imaging. J Am Chem Soc 1993;115:3300-3305.
13. 31P NMR 1D profling and PFG-SE in dextran gels. J Magn Reson 2003;162:198-205.
14. 31P NMR. J Phys Chem B 2009;113:9084-9091.
15. McDonald JJ, Pritchard T, Roberts SP. Difusion of water at low saturation levels into sandstone rock plugs measured by broad line magnetic resonance profling. J Colloid Interface Sci 1996;177:439-445. (Pubitemid 26166482)
16. Deka K, MacMillan MB, Ouriadov AV, Mastikhin IV, Young JJ, Glover PM, et al. Quantitative density profling with pure phase encoding and dedicated 1D gradient. J Magn Reson 2006;178:25-32. (Pubitemid 41774008)
17. 19F NMR imaging. J Pharm Pharmacol 1989;41:64P. (Pubitemid 20102771)
18. Dinarvand R, Wood B, D'Emanuele A. Measurement of difusion of 2,2,2-trifuoroacetamide within thermoresponsive hydrogels using NMR imaging. Pharm Res 1995;12:1376-1379.
19. Lin JH. Bisphosphonate: A review of their pharmacokinetic properties. Bone 1996;18:75-85. (Pubitemid 26092586)
20. Spicer EJF, Goldenthal EI, Ikeda T. A toxicological assessment of curdlan. Food Chem Toxicol 1999;37:455-479. (Pubitemid 29335768)
21. Maeda I, Saito H, Masada M, Misaki A, Harada T. Properties of gels formed by heat treatement of curdlan, a bacterial β-1,3 glucan. Agric Biol Chem 1967;31:1184-1188.
22. Hirashima M, Takaya T, Nishinari K. DSC and rheological studies on aqueous dispersions of curdlan. Termochim Acta 1997;306: 109-114. (Pubitemid 127345671)
23. Gagnon M-A, Lafeur M. From curdlan powder to the triple helix gel structure: An attenuated total relection-infrared study of the gelation process. Appl Spectrosc 2007;61:374-378. (Pubitemid 46615482)
24. Kanke M, Tanabe E, Katayama H, Koda Y, Yoshitomi H. Application of curdlan to controlled drug delivery. III Drug release from sustained release suppositories in vitro. Biol Pharm Bull 1995;18:1154-1158.
25. Hollewand MP, Gladden L F. Transport heterogeneity in porous pellets-I. PGSE NMR studies. Chem Eng Sci 1995;50:309-326.
26. Hollewand MP, Gladden L F. Transport heterogeneity in porous pellets-II. NMR imaging studies under transient and steady-state conditions. Chem Eng Sci 1995;50:327-344.
27. Ammann C, Meier P, Merbach AE. A simple multinuclear NMR thermometer. J Magn Reson 1982;46:319-321.
28. Talagala SL, Lowe IJ. Introduction to magnetic resonance imaging. Concepts Magn Reson 1991;3:145-159.
29. Ghai RK, Ertl H, Dullien FAL. Liquid difusion of non-electrolytes: Part I. AIChE J 1973;19:881-900.
30. Ostovic D, Stelmach C, Hulshizer B. Formation of chromophoric complex between alendronate and copper(II) ions. Pharm Res 1993;1993:470-472.
31. Fu JC, Hagemeir C, Moyer DL. A unifed mathematical model for difusion from drug-polymer composite tablets. J Biomed Mater Res 1976;10:743-758.
32. Jerschow A, Müller N. Suppression of convection artifacts in stimulated-echo difusion experiments. Double-stimulated-echo experiments. J Magn Reson 1997;125:372-375. (Pubitemid 127451901)
33. Tanner JE. Use of the stimulated echo in NMR diffusion studies. J Chem Phys 1970;52:2523-2526.
34. Ritger PL, Peppas NA. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Controlled Release 1987;5:23-36. (Pubitemid 17106643)
35. Casault S, Slater GW. Systematic characterization of drug release profles from fnite-sized hydrogels. Physica A 2008;387: 5387-5402.
36. Mastikhin IV, Mullally B, MacMillan B, Balcom BJ. Water content profles with a 1D centric SPRITE acquisition. J Magn Reson. 2002;156:122-130.