Origin and removal of mixed-phase artifacts in gradient sensitivity enhanced heteronuclear single quantum correlation spectra

Journal of Biomolecular NMR

Volumn 51, Issue 1-2, 2011, Pages 199-207

  Mulder, Frans A A ^a   Otten, Renee ^a,b   Scheek, Ruud M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

Artifact; HSQC; Line shape; Phase error; Sensitivity enhancement

Indexed keywords

15N HETERONUCLEAR SINGLE QUANTUM COHERENCE; 1H HETERONUCLEAR SINGLE QUANTUM COHERENCE; ARTICLE; ARTIFACT; DENSITY GRADIENT; HETERONUCLEAR SINGLE QUANTUM COHERENCE; OPERATOR; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SENSITIVITY ANALYSIS; SIGNAL DETECTION;

ARTIFACTS; MAGNETIC RESONANCE SPECTROSCOPY; REPRODUCIBILITY OF RESULTS;

EID: 80755181324     PISSN: 09252738     EISSN: 15735001     Source Type: Journal    
DOI: 10.1007/s10858-011-9554-9     Document Type: Article

References (20)

1. A Bax SS Pochapsky 1992 Optimized recording of heteronuclear multidimensional NMR spectra using pulsed field gradients J Magn Reson 99 3 638 643 10.1016/0022-2364(92)90221-R
2. G Bodenhausen DJ Ruben 1980 Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy Chem Phys Lett 69 1 185 189 1980CPL....69..185B 10.1016/0009-2614(80)80041-8
3. M Czisch R Boelens 1998 Sensitivity enhancement in the TROSY experiment J Magn Reson 134 1 158 160 1998JMagR.134..158C 10.1006/jmre.1998.1483 (Pubitemid 128451268)
4. KT Dayie G Wagner 1994 Relaxation-rate measurements for 15 N-1H groups with pulsed-field gradients and preservation of coherence pathways J Magn Reson, Ser A 111 1 121 126 10.1006/jmra.1994.1236
5. H Geen R Freeman 1991 Band-selective radiofrequency pulses J Magn Reson 93 1 93 141 10.1016/0022-2364(91)90034-Q
6. LE Kay P Keifer T Saarinen 1992 Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity J Am Chem Soc 114 26 10663 10665 10.1021/ja00052a088
7. D Marion M Ikura R Tschudin A Bax 1989 Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins J Magn Reson 85 2 393 399 10.1016/0022-2364(89)90152-2
8. DR Muhandiram LE Kay 1994 Gradient-enhanced triple-resonance three-dimensional NMR experiments with improved sensitivity J Magn Reson Ser B 103 3 203 216 10.1006/jmrb.1994.1032
9. DR Muhandiram GY Xu LE Kay 1993 An enhanced-sensitivity pure absorption gradient 4D 15 N, 13C-edited NOESY experiment J Biomol NMR 3 4 463 470 10.1007/BF00176011
10. FAA Mulder CAEM Spronk M Slijper R Kaptein R Boelens 1996 Improved HSQC experiments for the observation of exchange broadened signals J Biomol NMR 8 2 223 228 10.1007/BF00211169 (Pubitemid 126706792)
11. NA Oktaviani R Otten K Dijkstra RM Scheek E Thulin M Akke FAA Mulder 2011 100% complete assignment of non-labile H-1, C-13, and N-15 signals for calcium-loaded calbindin D-9 k P43G Biomol NMR Assign 5 1 79 84 10.1007/s12104-010-9272-3
12. AG Palmer J Cavanagh PE Wright M Rance 1991 Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy J Magn Reson 93 1 151 170 10.1016/0022-2364(91)90036-S
13. M Salzmann G Wider K Pervushin K Wüthrich 1999 Improved sensitivity and coherence selection for [15 N, 1H]-TROSY elements in triple resonance experiments J Biomol NMR 15 2 181 184 10.1023/A:1008358030477
14. M Sattler P Schmidt J Schleucher O Schedletzky SJ Glaser C Griesinger 1995 Novel pulse sequences with sensitivity enhancement for in-phase coherence transfer employing pulsed field gradients J Magn Reson Ser B 108 3 235 242 10.1006/jmrb.1995.1128
15. J Schleucher M Schwendinger M Sattler P Schmidt O Schedletzky SJ Glaser OW Sorensen C Griesinger 1994 A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients J Biomol NMR 4 2 301 306 10.1007/BF00175254
16. DJ States RA Haberkorn DJ Ruben 1982 A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants J Magn Reson 48 2 286 292 10.1016/0022-2364(82)90279-7
17. J Stonehouse RT Clowes GL Shaw J Keeler ED Laue 1995 Minimisation of sensitivity losses due to the use of gradient pulses in triple-resonance NMR of proteins J Biomol NMR 5 3 226 232 10.1007/BF00211750
18. J Weigelt 1998 Single scan, sensitivity- and gradient-enhanced TROSY for multidimensional NMR experiments J Am Chem Soc 120 41 10778 10779 10.1021/ja982649y (Pubitemid 28498833)
19. Wolfram Research, Inc. (2010) Mathematica, version 8. Champaign
20. O Zhang LE Kay JP Olivier JD Forman-Kay 1994 Backbone 1H and 15 N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques J Biomol NMR 4 6 845 858 10.1007/BF00398413