Evaluation of the teratogenic potential of N-[N-[3-(3-hydroxy-4-methoxyphenyl) propyl]-α-aspartyl]-l-phenylalanine 1-methyl ester, monohydrate (advantame) in the rat and rabbit

Food and Chemical Toxicology

Volumn 49, Issue SUPPL. 1, 2011, Pages

  Otabe, A ^a   Fujieda, T ^a   Masuyama, T ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Advantame; N N 3 (3 hydroxy 4 methoxyphenyl) propyl aspartyl l phenylalanine 1 methyl ester; Rabbit; Rat; Teratology

Indexed keywords

ADVANTAME; SWEETENING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLEEDING; BONE DISEASE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DIAPHRAGM DISEASE; EMBRYOTOXICITY; EYE MALFORMATION; FECES COLOR; FEMALE; FETOTOXICITY; FETUS; FETUS DEATH; FOOD INTAKE; KIDNEY DISEASE; LIVER DISEASE; MARE; MATERNAL TOXICITY; NONHUMAN; RABBIT; RAT; SKIN COLOR; TERATOGENICITY; TESTIS DISEASE; THYMUS DISEASE; THYROID DISEASE; TOXICITY; TOXICITY TESTING; UMBILICAL ARTERY; URETER DILATATION; URINE COLOR;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FETAL DEATH; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; RABBITS; RATS; REPRODUCTION; SWEETENING AGENTS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 80755180842     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.06.041     Document Type: Article

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