Swelling control in thermo-responsive hydrogels based on 2-(2-methoxyethoxy)ethyl methacrylate by crosslinking and copolymerization with N-isopropylacrylamide

Polymer Journal

Volumn 43, Issue 11, 2011, Pages 887-892

  García García, José M ^a   Liras, Marta ^a   Quijada Garrido, Isabel ^a   Gallardo, Alberto ^a   París, Rodrigo ^a  

^a INSTITUTO DE CIENCIA Y TECNOLOGÍA DE POLÍMEROS   (Spain)

Author keywords

2 (2 methoxyethoxy)ethyl methacrylate; N isopropylacrylamide; polyhedral oligomeric silsesquioxane; tetra(ethylene glycol)dimethacrylate; thermo responsive hydrogels; volume transition temperature

Indexed keywords

2-(2-METHOXYETHOXY)ETHYL METHACRYLATE; N-ISOPROPYLACRYLAMIDES; POLYHEDRAL OLIGOMERIC SILSESQUIOXANES; TETRA(ETHYLENE GLYCOL)DIMETHACRYLATE; THERMO-RESPONSIVE; VOLUME TRANSITIONS;

ACRYLIC MONOMERS; AMIDES; COPOLYMERIZATION; COPOLYMERS; ETHYLENE; ETHYLENE GLYCOL; GLASS TRANSITION; OLIGOMERS; SWELLING; TEMPERATURE;

HYDROGELS;

EID: 80755168062     PISSN: 00323896     EISSN: 13490540     Source Type: Journal    
DOI: 10.1038/pj.2011.83     Document Type: Article

References (40)

1. Hoffman, A. S. Hydrogels for biomedical applications. Adv. Drug Deliver. Rev. 54, 3-12 (2002 (Pubitemid 34081178)
2. Jeong, B., Kim, S. W. & Bae, Y. H. Thermosensitive sol-gel reversible hydrogels. Adv. Drug Deliver. Rev. 54, 37-51 (2002 (Pubitemid 34075313)
3. Imran, A. B., Seki, T. & Takeoka, Y. Recent advances in hydrogels in terms of fast stimuli responsiveness and superior mechanical performance. Polym. J. 42, 839-851 (2010
4. Yoshida, R. Development of self-oscillating polymers and gels with autonomous function. Polym. J. 42, 777-789 (2010
5. Tanaka, T. Collapse of gels and the critical endpoint. Phys. Rev. Lett. 40, 820-823 (1978
6. Kawaguchi, T., Kojima, Y., Osa, M. & Yoshizaki, T. Cloud points in aqueous poly (N-isopropylacrylamide) solutions. Polym. J. 40, 455-459 (2008
7. Peppas, N. A. Hydrogels. in Biomaterials Science: An Introduction to Materials in Medicine (eds Ratner, B. D., Hoffman, A. S., Schoen, F. J. & Lemons, J. E.) 2nd edn, 100-107 (Academic Press, New York, NY, 2004
8. Sayil, C. & Okay, O. The effect of preparation temperature on the swelling behavior of poly(N-isopropylacrylamide) gels. Polym. Bull. 45, 175-182 (2000
9. Gutowska, A., Bae, Y. H., Feijen, J. & Kim, S. W. Heparin release from thermosensitive hydrogels. J. Control Release 22, 95-104 (1992
10. Sershen, S. R., Westcott, S. L., Halas, N. J. & West, J. L. Temperature-sensitive polymer-nanoshell composites for photothermally modulated drug delivery. J. Biomed. Mater. Res. 51, 293-298 (2000 (Pubitemid 30452130)
11. Ali, M., Horikawa, S., Venkatesh, S., Saha, J., Hong, J. W. & Byrne, M. E. Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow. J. Control Release 124, 154-162 (2007 (Pubitemid 350110488)
12. Stile, R. A. & Healy, K. E. Poly(N-isopropylacrylamide)-based semi-interpenetrating polymer networks for tissue engineering applications. 1. Effects of linear poly (acrylic acid) chains on phase behavior. Biomacromolecules 3, 591-600 (2002 (Pubitemid 34567464)
13. Iveković , D., Milardović , S. & Grabarić , B. S. Palladium hexacyanoferrate hydrogel as a novel and simple enzyme immobilization matrix for amperometric biosensors. Biosens. Bioelectron. 20, 871-877 (2004 (Pubitemid 39441268)
14. Takahara, J., Takayama, K., Isowa, K. & Nagai, T. Multi-objective simultaneous optimization based on artificial neural network in a ketoprofen hydrogel formula containing O-ethyl menthol as a percutaneous absorption enhancer. Int. J. Pharm. 158, 203-210 (1997 (Pubitemid 28012907)
15. Jiang H., Campbell G., Boughner D., Wan W. K., Quantz M. Design and manufacture of a polyvinyl alcohol (PVA) cryogel tri-leaflet heart valve prosthesis. Med. Eng. Phys. 26 269-277 2004 (Pubitemid 38581035)
16. Mao, L., Hu, Y., Piao, Y., Chen, X., Xian, W. & Piao, D. Structure and character of artificial muscle model constructed from fibrous hydrogel. Curr. Appl. Phys. 5, 426-428 (2005 (Pubitemid 40714966)
17. Pérez, P., Gallardo, A., Corrigan, O. I. & Román, J. S. Thermosensitivity of N-isopropylacrylamide hydrogels cross-linked with degradable cross-linker. J. Biomat. Sci.Polym. E. 19, 769-783 (2008 (Pubitemid 351820782)
18. Paŕs, R., Barrales-Rienda, J. M. & Quijada-Garrido, I. Dynamic swelling of hydrogels based on random terpolymers of N-isopropylacrylamide, methacrylic acid and poly(ethylene glycol) macromonomer. Polymer 50, 2065-2074 (2009
19. Paŕs, R. & Quijada-Garrido, I. Swelling behaviour of thermo-sensitive hydrogels based on oligo(ethylene glycol) methacrylates. Eur. Polym. J. 45, 3418-3425 (2009
20. Paŕs, R. & Quijada-Garrido, I. Temperature-and pH-responsive behaviour of poly (2-(2-methoxyethoxy)ethyl methacrylate-co-N,N- dimethylaminoethyl methacrylate) hydrogels. Eur. Polym. J. 46, 2156-2163 (2010
21. Quijada-Garrido, I., Prior-Cabanillas, A., Paris, R., Frutos, G. & Barrales-Rienda, J. M. Water transport properties of pH-responsive hydrogels based on poly(methacrylic acid) with polyether side chains by magnetic resonance imaging. Macromol. Chem. Phys. 210, 520-530 (2009
22. Paŕs, R., Garća, J. & Quijada-Garrido, I. Thermo-and pH-sensitive hydrogels based on 2-(2-methoxyethoxy)ethyl methacrylate and methacrylic acid. Polym. Int. 60, 178-185 (2011
23. Lutz, J. F. & Hoth, A. Preparation of ideal PEG analogues with a tunable thermosensitivity by controlled radical copolymerization of 2-(2-methoxyethoxy)ethyl methacrylate and oligo(ethylene glycol) methacrylate. Macromolecules 39, 893-896 (2006 (Pubitemid 43164604)
24. Dong, H. & Matyjaszewski, K. Thermally responsive P(M(EO)2MA-co-OEOMA) copolymers via AGET ATRP in miniemulsion. Macromolecules 43, 4623-4628 (2010
25. Lutz, J. F., Andrieu, J., Üzgün, S., Rudolph, C. & Agarwal, S. Biocompatible, thermoresponsive, and biodegradable: simple preparation of 'All-in-one' biorelevant polymers. Macromolecules 40, 8540-8543 (2007 (Pubitemid 350241352)
26. Lutz, J. F., Stiller, S., Hoth, A., Kaufner, L., Pison, U. & Cartier, R. One-pot synthesis of PEGylated ultrasmall iron-oxide nanoparticles and their in vivo evaluation as magnetic resonance imaging contrast agents. Biomacromolecules 7, 3132-3138 (2006 (Pubitemid 46039971)
27. Ishizone, T., Seki, A., Hagiwara, M., Han, S., Yokoyama, H., Oyane, A., Deffieux, A. & Carlotti, S. Anionic polymerizations of oligo(ethylene glycol) alkyl ether methacrylates: effect of side chain length and o-alkyl group of side chain on cloud point in water. Macromolecules 41, 2963-2967 (2008 (Pubitemid 351685061)
28. Badi, N. & Lutz, J. F. PEG-based thermogels: applicability in physiological media. J. Control Release 140, 224-229 (2009
29. Kabiri K., Omidian H., Hashemi S. A., Zohuriaan-Mehr M. J Synthesis of fast-swelling superabsorbent hydrogels: effect of crosslinker type and concentration on porosity and absorption rate. Eur. Polym. J. 39, 1341-1348 2003
30. Ç aykara, T. & Turan, E. Effect of the amount and type of the crosslinker on the swelling behavior of temperature-sensitive poly(N-tert-butylacrylamide-co-acrylamide) hydrogels. Colloid Polym. Sci. 284, 1038-1048 (2006 (Pubitemid 44056628)
31. Atta, A. M. & Abdel-Azim, A. A. A. Effect of crosslinker functionality on swelling and network parameters of copolymeric hydrogels. Polym. Advan. Technol. 9, 340-348 (1998 (Pubitemid 128495957)
32. Aouada, F. A., Chiou, B. S., Orts, W. J. & Mattoso, L. H. C. Physicochemical morphological properties of poly(acrylamide) methylcellulose hydrogels: effects of monomer, crosslinker and polysaccharide compositions. Polym. Eng. Sci. 49, 2467-2474 (2009
33. Nash, M. E., Velasco, D., Gomez, J., Gorelov, A., Elezov, D., Gallardo, A., Rochev, Y. & Elvira, C. Synthesis and characterization of a novel thermoresponsive copolymer series and their application in cell and cell sheet regeneration. J. Biomater. Sci. Polym. Ed. (submitted
34. Paŕs, R., De La Fuente, J. L Glass transition temperature of allyl methacrylate-nbutyl acrylate gradient copolymers in dependence on chemical composition and molecular weight J. Polym. Sci. Pol. Phys. 45 1845-1855 2007 (Pubitemid 47169819)
35. Sastre, R., Mart́n, V., Garrido, L., Chiara, J. L., Trastoy, B., Garća, O., Costela, A. & Moreno, I. G. Dye-doped polyhedral oligomeric silsesquioxane (POSS)-modified polymeric matrices for highly efficient and photostable solid-state lasers. Adv. Funct. Mater. 19, 3307-3316 (2009
36. Mahdavinia, G. R., Pourjavadi, A., Hosseinzadeh, H. & Zohuriaan, M. J. Modified chitosan 4. Superabsorbent hydrogels from poly(acrylic acid-co-acrylamide) grafted chitosan with salt-and pH-responsiveness properties. Eur. Polym. J. 40, 1399-1407 (2004
37. Rasool, N., Yasin, T., Heng, J. Y. Y. & Akhter, Z. Synthesis and characterization of novel pH-, ionic strength and temperature-sensitive hydrogel for insulin delivery. Polymer 51, 1687-1693 (2010
38. D́ez-Peña, E., Quijada-Garrido, I., Frutos, P. & Barrales-Rienda, J. M. Thermal properties of cross-linked poly(N- isopropylacrylamide) [P(N-iPAAm)], poly(methacrylic acid) [P(MAA)], their random copolymers [P(N-iPAAm-co-MAA)], and sequential interpenetrating polymer networks (IPNs). Macromolecules 35, 2667-2675 (2002 (Pubitemid 34590053)
39. Lutz, J. F., Akdemir, Ö. & Hoth, A. Point by point comparison of two thermosensitive polymers exhibiting a similar LCST: is the age of poly(NIPAM) over J. Am. Chem. Soc. 128, 13046-13047 (2006 (Pubitemid 44527663)
40. Liras, M., Garća-Garća, J. M., Quijada-Garrido, I., Gallardo, A. & Paŕs, R. Thermoresponsive allyl functionalized 2-(2-methoxyethoxy)ethyl methacrylate-based polymers as versatile precursors for smart polymer conjugates and conetworks. Macromolecules 44, 3739-3745 (2011