메뉴 건너뛰기




Volumn 18, Issue 4, 2011, Pages 57-65

Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions

Author keywords

adrenergic; Cardiomyocytes; Connexin43; G q; Gap junctions; Internalization; Norepinephrine; Ubiquitination

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; CONNEXIN 43; GAP JUNCTION PROTEIN; MEMBRANE LIPID; NORADRENALIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEASOME; TRITON X 100; UBIQUITIN PROTEIN LIGASE NEDD4;

EID: 80755159026     PISSN: 15419061     EISSN: 15435180     Source Type: Journal    
DOI: 10.3109/15419061.2011.611920     Document Type: Article
Times cited : (20)

References (44)
  • 2
    • 56649099046 scopus 로고    scopus 로고
    • Acute internalization of gap junctions in vascular endothelial cells in response to inf ammatory mediator-induced G-protein coupled receptor activation
    • Baker SM, Kim N, Gumpert AM, Segretain D, and Falk MM (2008). Acute internalization of gap junctions in vascular endothelial cells in response to inf ammatory mediator-induced G-protein coupled receptor activation. FEBS Letters. 582: 4039-4046.
    • (2008) FEBS Letters. , vol.582 , pp. 4039-4046
    • Baker, S.M.1    Kim, N.2    Gumpert, A.M.3    Segretain, D.4    Falk, M.M.5
  • 5
    • 1942438946 scopus 로고    scopus 로고
    • Pathways for degradation of connexins and gap junctions
    • DOI 10.1016/j.cardiores.2003.12.021, PII S0008636303007892
    • Berthoud VM, Minogue PJ, Laing JG, and Beyer EC (2004). Pathways for degradation of connexins and gap junctions. Cardiovascular Research. 62: 256-267. (Pubitemid 38496539)
    • (2004) Cardiovascular Research , vol.62 , Issue.2 , pp. 256-267
    • Berthoud, V.M.1    Minogue, P.J.2    Laing, J.G.3    Beyer, E.C.4
  • 6
    • 34249650290 scopus 로고    scopus 로고
    • KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes
    • DOI 10.1016/j.bbamcr.2007.02.008, PII S0167488907000481
    • Calloe K, Nielsen MS, Grunnet M, Schmitt N, and Jorgensen NK (2007). KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research. 1773: 764-773. (Pubitemid 46829433)
    • (2007) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1773 , Issue.6 , pp. 764-773
    • Calloe, K.1    Nielsen, M.S.2    Grunnet, M.3    Schmitt, N.4    Jorgensen, N.K.5
  • 7
    • 0031025039 scopus 로고    scopus 로고
    • Influence of α-adrenergic-receptor activation on junctional conductance in heart cells: Interaction with β-adrenergic agonists
    • DOI 10.1097/00005344-199702000-00017
    • De Mello WC (1997). Inf uence of alpha-adrenergic-receptor activation on junctional conductance in heart cells: interaction with beta-adrenergic adrenergic agonists. Journal of cardiovascular pharmacology. 29: 273-277. (Pubitemid 27097731)
    • (1997) Journal of Cardiovascular Pharmacology , vol.29 , Issue.2 , pp. 273-277
    • De Mello, W.C.1
  • 8
    • 0025149712 scopus 로고
    • Effects of arachidonic acid on the gap junctions of neonatal rat heart cells
    • Fluri GS, R ü dis ü li A, Willi M, Rohr S, and Weingart R (1990). Effects of arachidonic acid on the gap junctions of neonatal rat heart cells. Pf ü gers Archiv European Journal of Physiology. 417: 149-156.
    • (1990) Pf Ü Gers Archiv European Journal of Physiology. , vol.417 , pp. 149-156
    • Fluri Gs, R.1
  • 10
    • 0026672346 scopus 로고
    • Endothelins inhibit junctional permeability in cultured mouse astrocytes
    • Giaume C, Cordier J, and Glowinski J (1992). Endothelins Inhibit Junctional Permeability in Cultured Mouse Astrocytes. European Journal of Neuroscience. 4: 877-881.
    • (1992) European Journal of Neuroscience. , vol.4 , pp. 877-881
    • Giaume, C.1    Cordier, J.2    Glowinski, J.3
  • 11
    • 0037473023 scopus 로고    scopus 로고
    • Phosphorylation of connexin 43 acts as a stimuli for proteasome-dependent degradation of the protein in lens epithelial cells
    • Girao H and Pereira P (2003). Phosphorylation of connexin 43 acts as a stimuli for proteasome-dependent degradation of the protein in lens epithelial cells. Mol Vis. 9: 24-30. (Pubitemid 38097563)
    • (2003) Molecular Vision , vol.9 , pp. 24-30
    • Girao, H.1    Pereira, P.2
  • 12
    • 70449519976 scopus 로고    scopus 로고
    • Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
    • Girao H, Catarino S, and Pereira P (2009). Eps15 interacts with ubiquitinated Cx43 and mediates its internalization. Experimental Cell Research. 315: 3587-3597.
    • (2009) Experimental Cell Research. , vol.315 , pp. 3587-3597
    • Girao, H.1    Catarino, S.2    Pereira, P.3
  • 13
    • 0028090673 scopus 로고
    • Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: Possible involvement of the mitogen-activated protein kinase cascade
    • Hii CS, OH S, Schmidt SA, Clark TJ, and Murray AW (1994). Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade. The Biochemical Journal. 303: 475-479. (Pubitemid 24317328)
    • (1994) Biochemical Journal , vol.303 , Issue.2 , pp. 475-479
    • Hii, C.S.T.1    Oh, S.-Y.2    Schmidt, S.A.3    Clark, K.J.4    Murray, A.W.5
  • 16
    • 85047687838 scopus 로고    scopus 로고
    • Role of the ubiquitin-proteasome pathway in downregulation of the gap-junction Protein Connexin43 by TNF-alpha in Human Corneal Fibroblasts
    • Kimura K and Nishida T (2010). Role of the Ubiquitin-Proteasome Pathway in Downregulation of the Gap-Junction Protein Connexin43 by TNF-alpha in Human Corneal Fibroblasts. Investigative Ophthalmology & Visual Science. 51: 1943-1947.
    • (2010) Investigative Ophthalmology & Visual Science. , vol.51 , pp. 1943-1947
    • Kimura, K.1    Nishida, T.2
  • 17
    • 77953707183 scopus 로고    scopus 로고
    • Regulation of gap junction intercellular communication by the ubiquitin system
    • Kjenseth A, Fykerud T, Rivedal E, and Leithe E (2010). Regulation of gap junction intercellular communication by the ubiquitin system. Cellular Signalling. 22: 1267-1273.
    • (2010) Cellular Signalling. , vol.22 , pp. 1267-1273
    • Kjenseth, A.1    Fykerud, T.2    Rivedal, E.3    Leithe, E.4
  • 18
    • 0028817813 scopus 로고
    • The Gap Junction Protein Connexin43 Is Degraded via the Ubiquitin Proteasome Pathway
    • Laing JG and Beyer EC (1995). The Gap Junction Protein Connexin43 Is Degraded via the Ubiquitin Proteasome Pathway. J. Biol. Chem. 270: 26399-26403.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26399-26403
    • Laing, J.G.1    Beyer, E.C.2
  • 19
    • 0032103769 scopus 로고    scopus 로고
    • Proteolysis of connexin43-containing gap junctions in normal and heat- stressed cardiac myocytes
    • DOI 10.1016/S0008-6363(98)00060-1, PII S0008636398000601
    • Laing JG, Tadros PN, Green K, Safftz JE, and Beyer EC (1998). Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes. Cardiovascular Research. 38: 711-718. (Pubitemid 28319880)
    • (1998) Cardiovascular Research , vol.38 , Issue.3 , pp. 711-718
    • Laing, J.G.1    Tadros, P.N.2    Green, K.3    Saffitz, J.E.4    Beyer C, E.5
  • 20
    • 0031281674 scopus 로고    scopus 로고
    • Degradation of connexin43 gap junctions involves both the proteasome and the lysosome
    • DOI 10.1006/excr.1997.3747
    • Laing JG, Tadros PN, Westphale EM, and Beyer EC (1997). Degradation of Connexin43 Gap Junctions Involves both the Proteasome and the Lysosome. Experimental Cell Research. 236: 482-492. (Pubitemid 27505601)
    • (1997) Experimental Cell Research , vol.236 , Issue.2 , pp. 482-492
    • Laing, J.G.1    Tadros, P.N.2    Westphale, E.M.3    Beyer, E.C.4
  • 21
    • 0026025267 scopus 로고
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
    • Laird DW, Puranam KL, and Revel JP (1991). Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. Biochem J. 273: 67-72.
    • (1991) Biochem J. , vol.273 , pp. 67-72
    • Laird, D.W.1    Puranam, K.L.2    Revel, J.P.3
  • 22
    • 33748795808 scopus 로고    scopus 로고
    • Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart
    • DOI 10.1242/jcs.03089
    • Lampe PD, Cooper CD, King TJ, and Burt JM (2006). Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart. J Cell Sci. 119: 3435-3442. (Pubitemid 44405227)
    • (2006) Journal of Cell Science , vol.119 , Issue.16 , pp. 3435-3442
    • Lampe, P.D.1    Copper, C.D.2    King, T.J.3    Burt, J.M.4
  • 23
    • 41649104490 scopus 로고    scopus 로고
    • Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes
    • DOI 10.1091/mbc.E07-06-0596
    • Langlois S, Cowan KN, Shao Q, Cowan BJ, and Laird DW (2008). Caveolin-1 and-2 Interact with Connexin43 and Regulate Gap Junctional Intercellular Communication in Keratinocytes. Mol. Biol. Cell. 19: 912-928. (Pubitemid 351481808)
    • (2008) Molecular Biology of the Cell , vol.19 , Issue.3 , pp. 912-928
    • Langlois, S.1    Cowan, K.N.2    Shao, Q.3    Cowan, B.J.4    Laird, D.W.5
  • 24
    • 30044446000 scopus 로고    scopus 로고
    • Endocytic processing of connexin43 gap junctions: A morphological study
    • DOI 10.1042/BJ20050674
    • Leithe E, Brech A, and Rivedal E (2006). Endocytic processing of connexin43 gap junctions: a morphological study. Biochem. J. 393: 59-67. (Pubitemid 43049302)
    • (2006) Biochemical Journal , vol.393 , Issue.1 , pp. 59-67
    • Leithe, E.1    Brech, A.2    Rivedal, E.3
  • 25
    • 70450277811 scopus 로고    scopus 로고
    • Ubiquitylation of the gap junction protein connexin43 signals its traff cking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
    • Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, and Rivedal E (2009). Ubiquitylation of the gap junction protein connexin43 signals its traff cking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101. J Cell Sci. 122: 3883-3893.
    • (2009) J Cell Sci. , vol.122 , pp. 3883-3893
    • Leithe, E.1    Kjenseth, A.2    Sirnes, S.3    Stenmark, H.4    Brech, A.5    Rivedal, E.6
  • 26
    • 1842426943 scopus 로고    scopus 로고
    • Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43
    • DOI 10.1242/jcs.00951
    • Leithe E and Rivedal E (2004a). Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43. J Cell Sci. 117: 1211-1220. (Pubitemid 38456102)
    • (2004) Journal of Cell Science , vol.117 , Issue.7 , pp. 1211-1220
    • Leithe, E.1    Rivedal, E.2
  • 27
    • 9244265420 scopus 로고    scopus 로고
    • Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment
    • DOI 10.1074/jbc.M402006200
    • Leithe E and Rivedal E (2004b). Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment. J Biol Chem. 279: 50089-50096. (Pubitemid 39577820)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.48 , pp. 50089-50096
    • Leithet, E.1    Rivedal, E.2
  • 28
    • 0035033320 scopus 로고    scopus 로고
    • The role of altered intercellular coupling in arrhythmias induced by acute myocardial ischemia
    • DOI 10.1016/S0008-6363(00)00301-1, PII S0008636300003011
    • Lerner DL, Beardslee MA, and Safftz JE (2001). The role of altered intercellular coupling in arrhythmias induced by acute myocardial ischemia. Cardiovascular Research. 50: 263-269. (Pubitemid 32382153)
    • (2001) Cardiovascular Research , vol.50 , Issue.2 , pp. 263-269
    • Lerner, D.L.1    Beardslee, M.A.2    Saffitz, J.E.3
  • 29
    • 33749386740 scopus 로고    scopus 로고
    • Ubiquitin protein ligase Nedd4 binds to connexin43 by a phosphorylation-modulated process
    • DOI 10.1242/jcs.03149
    • Leykauf K, Salek M, Bomke J, Frech M, Lehmann WD, Durst M, and Alonso A (2006). Ubiquitin protein ligase Nedd4 binds to connexin43 by a phosphorylation-modulated process. J Cell Sci. 119: 3634-3642. (Pubitemid 44501867)
    • (2006) Journal of Cell Science , vol.119 , Issue.17 , pp. 3634-3642
    • Leykauf, K.1    Salek, M.2    Bomke, J.3    Frech, M.4    Lehmann, W.-D.5    Durst, M.6    Alonso, A.7
  • 31
    • 2342624615 scopus 로고    scopus 로고
    • ATP-induced inhibition of gap junctional communication is enhanced by interleukin-1 β treatment in cultured astrocytes
    • DOI 10.1016/j.neuroscience.2004.03.031, PII S0306452204002325
    • Meme W, Ezan P, Venance L, Glowinski J, and Giaume C (2004). ATP-induced inhibition of gap junctional communication is enhanced by interleukin-1 beta treatment in cultured astrocytes. Neuroscience. 126, 95-104. (Pubitemid 38609109)
    • (2004) Neuroscience , vol.126 , Issue.1 , pp. 95-104
    • Meme, W.1    Ezan, P.2    Venance, L.3    Glowinski, J.4    Giaume, C.5
  • 32
    • 0025789648 scopus 로고
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
    • Musil LS and Goodenough DA (1991). Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J. Cell Biol. 115: 1357-1374. (Pubitemid 21909980)
    • (1991) Journal of Cell Biology , vol.115 , Issue.5 , pp. 1357-1374
    • Musil, L.S.1    Goodenough, D.A.2
  • 33
    • 0023161934 scopus 로고
    • Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea-pig
    • Noma A and Tsuboi N (1987). Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea-pig. J Physiol (Lond). 382: 193-211. (Pubitemid 17226143)
    • (1987) Journal of Physiology , vol.382 , pp. 193-211
    • Noma, A.1    Tsuboi, N.2
  • 34
    • 0034915764 scopus 로고    scopus 로고
    • Mechanisms underlying ubiquitination
    • DOI 10.1146/annurev.biochem.70.1.503
    • Pickart CM (2001). Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70: 503-533. (Pubitemid 32663902)
    • (2001) Annual Review of Biochemistry , vol.70 , pp. 503-533
    • Pickart, C.M.1
  • 36
    • 0042030808 scopus 로고    scopus 로고
    • Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells
    • DOI 10.1074/jbc.M300614200
    • Qin H, Shao Q, Igdoura SA, aoui-Jamali MA, and Laird DW (2003). Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-def cient and-competent breast tumor cells. J Biol Chem. 278: 30005-30014. (Pubitemid 36962390)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.32 , pp. 30005-30014
    • Qin, H.1    Shao, Q.2    Igdoura, S.A.3    Alaoui-Jamali, M.A.4    Laird, D.W.5
  • 38
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs NJ, Bruce AF, Dupont E, and Rothery S (2008). Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovascular Research. 80: 9-19.
    • (2008) Cardiovascular Research. , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 39
    • 33745089231 scopus 로고    scopus 로고
    • Regulation of functional diversity within the Nedd4 family by accessory and adaptor proteins
    • DOI 10.1002/bies.20422
    • Shearwin-Whyatt L, Dalton HE, Foot N, and Kumar S (2006). Regulation of functional diversity within the Nedd4 family by accessory and adaptor proteins. BioEssays. 28: 617-628. (Pubitemid 43886187)
    • (2006) BioEssays , vol.28 , Issue.6 , pp. 617-628
    • Shearwin-Whyatt, L.1    Dalton, H.E.2    Foot, N.3    Kumar, S.4
  • 40
    • 50949106174 scopus 로고    scopus 로고
    • The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
    • Sirnes S, Leithe E, and Rivedal E (2008). The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis. Biochem. Biophys. Res Commun. 373: 597-601.
    • (2008) Biochem. Biophys. Res Commun. , vol.373 , pp. 597-601
    • Sirnes, S.1    Leithe, E.2    Rivedal, E.3
  • 41
    • 0142135067 scopus 로고    scopus 로고
    • Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells
    • Spinella F, Rosan ò L, Di Castro V, Nicotra MR, Natali PG, and Bagnato A (2003). Endothelin-1 Decreases Gap Junctional Intercellular Communication by Inducing Phosphorylation of Connexin 43 in Human Ovarian Carcinoma Cells. J. Biol. Chem. 278: 41294-41301.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41294-41301
    • Spinella F, R.1
  • 43
    • 0034106939 scopus 로고    scopus 로고
    • Analysis of connexin intracellular transport and assembly
    • DOI 10.1006/meth.1999.0933
    • VanSlyke JK, and Musil LS (2000). Analysis of Connexin Intracellular Transport and Assembly. Methods. 20: 156-164. (Pubitemid 30130808)
    • (2000) Methods , vol.20 , Issue.2 , pp. 156-164
    • Vanslyke, J.K.1    Musil, L.S.2
  • 44
    • 0027511801 scopus 로고
    • Inhibition of gap junctional conductance by long-chain acylcarnitines and their preferential accumulation in junctional sarcolemma during hypoxia
    • Wu J, McHowat J, Safftz JE, Yamada KA, and Corr PB (1993). Inhibition of gap junctional conductance by long-chain acylcarnitines and their preferential accumulation in junctional sarcolemma during hypoxia. Circ Res. 72: 879-889. (Pubitemid 23077778)
    • (1993) Circulation Research , vol.72 , Issue.4 , pp. 879-889
    • Wu, J.1    McHowat, J.2    Saffitz, J.E.3    Yamada, K.A.4    Corr, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.