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Volumn 6, Issue 1, 2011, Pages 119-124

Clinical utility of denosumab for treatment of bone loss in men and women

Author keywords

Androgen deprivation therapy; Bisphosphonates; Denosumab; Dual energy x ray absorptiometry; Fracture; Osteonecrosis of the jaw; Osteoporosis

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; DENOSUMAB; PLACEBO;

EID: 80755143281     PISSN: 11769092     EISSN: 11781998     Source Type: Journal    
DOI: 10.2147/CIA.S14565     Document Type: Review
Times cited : (27)

References (47)
  • 1
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22(10):1479-1491.
    • (2007) J Bone Miner Res , vol.22 , Issue.10 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 2
    • 77953190774 scopus 로고    scopus 로고
    • Adverse effects of bisphosphonates
    • Abrahamsen B. Adverse effects of bisphosphonates. Calcif Tissue Int. 2010;86(6):421-435.
    • (2010) Calcif Tissue Int , vol.86 , Issue.6 , pp. 421-435
    • Abrahamsen, B.1
  • 3
    • 78349249359 scopus 로고    scopus 로고
    • Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research
    • Shane E, Burr D, Ebeling PR, et al. Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2010;25(11):2267-2294.
    • (2010) J Bone Miner Res , vol.25 , Issue.11 , pp. 2267-2294
    • Shane, E.1    Burr, D.2    Ebeling, P.R.3
  • 4
    • 78751576040 scopus 로고    scopus 로고
    • Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group report
    • Rizzoli R, Akesson K, Bouxsein M, et al. Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group report. Osteoporos Int. 2011;22(2):373-390.
    • (2011) Osteoporos Int , vol.22 , Issue.2 , pp. 373-390
    • Rizzoli, R.1    Akesson, K.2    Bouxsein, M.3
  • 5
    • 84872155028 scopus 로고    scopus 로고
    • Oral bisphosphonates and risk of cancer of esophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort
    • Green J, Czanner G, Reeves G, Watson J, Wise L, Beral V. Oral bisphosphonates and risk of cancer of esophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort. BMJ. 2010;1:341.
    • (2010) BMJ , vol.1 , pp. 341
    • Green, J.1    Czanner, G.2    Reeves, G.3    Watson, J.4    Wise, L.5    Beral, V.6
  • 6
    • 77955369368 scopus 로고    scopus 로고
    • Exposure to oral bisphosphonates and risk of esophageal cancer
    • Cardwell CR, Abnet CC, Cantwell MM, Murray LJ. Exposure to oral bisphosphonates and risk of esophageal cancer. JAMA. 2010;304(6):657-663.
    • (2010) JAMA , vol.304 , Issue.6 , pp. 657-663
    • Cardwell, C.R.1    Abnet, C.C.2    Cantwell, M.M.3    Murray, L.J.4
  • 7
    • 84857356093 scopus 로고    scopus 로고
    • Use of bisphosphonates and risk of atrial fibrillation in older women with osteoporosis
    • March 24, [Epub ahead of print]
    • Rhee CW, Lee J, Oh S, Choi NK, Park BJ. Use of bisphosphonates and risk of atrial fibrillation in older women with osteoporosis. Osteoporos Int. March 24, 2011. [Epub ahead of print].
    • (2011) Osteoporos Int
    • Rhee, C.W.1    Lee, J.2    Oh, S.3    Choi, N.K.4    Park, B.J.5
  • 8
    • 77951634320 scopus 로고    scopus 로고
    • Long-term use of bisphosphonates in osteoporosis
    • Watts NB, Diab DL. Long-term use of bisphosphonates in osteoporosis. J Clin Endocrinol Metab. 2010;95(4):1555-1565.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.4 , pp. 1555-1565
    • Watts, N.B.1    Diab, D.L.2
  • 9
    • 78651488703 scopus 로고    scopus 로고
    • Oral bisphosphonate compliance and persistence: A matter of choice?
    • Silverman SL, Schousboe JT, Gold DT. Oral bisphosphonate compliance and persistence: A matter of choice? Osteoporos Int. 2011;22(1):21-26.
    • (2011) Osteoporos Int , vol.22 , Issue.1 , pp. 21-26
    • Silverman, S.L.1    Schousboe, J.T.2    Gold, D.T.3
  • 10
    • 77950933699 scopus 로고    scopus 로고
    • Bisphosphonates and osteoporotic fractures: A cross-design synthesis of results among compliant/persistent postmenopausal women in clinical practice versus randomized controlled trials
    • Wilkes MM, Navickis RJ, Chan WW, Lewiecki EM. Bisphosphonates and osteoporotic fractures: A cross-design synthesis of results among compliant/persistent postmenopausal women in clinical practice versus randomized controlled trials. Osteoporos Int. 2010;21(4):679-688.
    • (2010) Osteoporos Int , vol.21 , Issue.4 , pp. 679-688
    • Wilkes, M.M.1    Navickis, R.J.2    Chan, W.W.3    Lewiecki, E.M.4
  • 11
    • 80755154431 scopus 로고    scopus 로고
    • Adherence, compliance, and persistence with osteoporosis therapies
    • In: Adler RA, editor, 2nd ed. New York, NY: Humana Press
    • Petkov VI, Williams MI. Adherence, compliance, and persistence with osteoporosis therapies. In: Adler RA, editor. Osteoporosis Pathophysiology and Clinical Management. 2nd ed. New York, NY: Humana Press; 2010.
    • (2010) Osteoporosis Pathophysiology and Clinical Management
    • Petkov, V.I.1    Williams, M.I.2
  • 12
    • 78650962009 scopus 로고    scopus 로고
    • Estimating bisphosphonate use and fracture reduction among US women aged 45 years and older
    • Siris ES, Pasquale MK, Wang Y, Watts NB. Estimating bisphosphonate use and fracture reduction among US women aged 45 years and older. J Bone Miner Res. 2011;26(1):3-11.
    • (2011) J Bone Miner Res , vol.26 , Issue.1 , pp. 3-11
    • Siris, E.S.1    Pasquale, M.K.2    Wang, Y.3    Watts, N.B.4
  • 13
    • 84857363230 scopus 로고    scopus 로고
    • GRAND: The German retrospective cohort analysis on compliance and persistence and the associated risk of fractures in osteoporotic women treated with oral bisphosphonates
    • February 10, [Epub ahead of print]
    • Hadji P, Claus V, Ziller V, Intorcia M, Kostev K, Steinle T. GRAND: The German retrospective cohort analysis on compliance and persistence and the associated risk of fractures in osteoporotic women treated with oral bisphosphonates. Osteoporos Int. February 10, 2011. [Epub ahead of print].
    • (2011) Osteoporos Int
    • Hadji, P.1    Claus, V.2    Ziller, V.3    Intorcia, M.4    Kostev, K.5    Steinle, T.6
  • 14
    • 58649113384 scopus 로고    scopus 로고
    • Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL
    • Kostenuik PJ, Nguyen HQ, McCabe J, et al. Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL. J Bone Miner Res. 2009;24(2):185-195.
    • (2009) J Bone Miner Res , vol.24 , Issue.2 , pp. 185-195
    • Kostenuik, P.J.1    Nguyen, H.Q.2    McCabe, J.3
  • 16
    • 12944262423 scopus 로고    scopus 로고
    • RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
    • Li J, Sarosi I, Yan XQ, et al. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci U S A. 2000;97(4):1566-1571.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.4 , pp. 1566-1571
    • Li, J.1    Sarosi, I.2    Yan, X.Q.3
  • 17
    • 0034915025 scopus 로고    scopus 로고
    • The effects of osteoprotegerin on the mechanical properties of rat bone
    • Ross AB, Bateman TA, Kostenuik PJ, et al. The effects of osteoprotegerin on the mechanical properties of rat bone. J Mater Sci Mater Med. 2001;12(7):583-588.
    • (2001) J Mater Sci Mater Med , vol.12 , Issue.7 , pp. 583-588
    • Ross, A.B.1    Bateman, T.A.2    Kostenuik, P.J.3
  • 18
    • 0033304632 scopus 로고    scopus 로고
    • Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    • Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Spelsberg TC, Riggs BL. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology. 1999;140(9):4367-4370.
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4367-4370
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lacey, D.L.4    Spelsberg, T.C.5    Riggs, B.L.6
  • 19
    • 77952744612 scopus 로고    scopus 로고
    • Treatment of osteoporosis with denosumab
    • Lewiecki EM. Treatment of osteoporosis with denosumab. Maturitas. 2010;66(2):182-186.
    • (2010) Maturitas , vol.66 , Issue.2 , pp. 182-186
    • Lewiecki, E.M.1
  • 20
    • 79952698455 scopus 로고    scopus 로고
    • Denosumab and bisphosphonates: Different mechanisms of action and effects
    • Baron R, Ferrari S, Russell RG. Denosumab and bisphosphonates: Different mechanisms of action and effects. Bone. 2011;48(4):677-692.
    • (2011) Bone , vol.48 , Issue.4 , pp. 677-692
    • Baron, R.1    Ferrari, S.2    Russell, R.G.3
  • 21
    • 34247194211 scopus 로고    scopus 로고
    • Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
    • Durge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007;22(3):465-475.
    • (2007) J Bone Miner Res , vol.22 , Issue.3 , pp. 465-475
    • Durge, R.1    Dawson-Hughes, B.2    Solomon, D.H.3    Wong, J.B.4    King, A.5    Tosteson, A.6
  • 22
    • 80052335491 scopus 로고    scopus 로고
    • Mortality rates after incident non-traumatic fractures in older men and women
    • December 16, [Epub ahead of print]
    • Morin S, Lix LM, Azimaee M, Metge C, Caetano P, Leslie WD. Mortality rates after incident non-traumatic fractures in older men and women. Osteoporos Int. December 16, 2010. [Epub ahead of print].
    • (2010) Osteoporos Int
    • Morin, S.1    Lix, L.M.2    Azimaee, M.3    Metge, C.4    Caetano, P.5    Leslie, W.D.6
  • 23
    • 77950903333 scopus 로고    scopus 로고
    • Meta-analysis: Excess mortality after hip fracture among older women and men
    • Haentjens P, Magaziner J, Colon-Emeric CS, et al. Meta-analysis: Excess mortality after hip fracture among older women and men. Ann Intern Med. 2010;152(6):380-390.
    • (2010) Ann Intern Med , vol.152 , Issue.6 , pp. 380-390
    • Haentjens, P.1    Magaziner, J.2    Colon-Emeric, C.S.3
  • 24
    • 39349086278 scopus 로고    scopus 로고
    • Systematic review: Comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis
    • MacLean C, Newberry S, Maglione M, et al. Systematic review: Comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis. Ann Intern Med. 2008;148(3):197-213.
    • (2008) Ann Intern Med , vol.148 , Issue.3 , pp. 197-213
    • McLean, C.1    Newberry, S.2    Maglione, M.3
  • 25
    • 79953835860 scopus 로고    scopus 로고
    • Bisphosphonates for post-menopausal osteoporosis: Are they all the same?
    • Rizzoli R. Bisphosphonates for post-menopausal osteoporosis: Are they all the same? QJM. 2011;104(4):281-300.
    • (2011) QJM , vol.104 , Issue.4 , pp. 281-300
    • Rizzoli, R.1
  • 26
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009;361(8):756-765.
    • (2009) N Engl J Med , vol.361 , Issue.8 , pp. 756-765
    • Cummings, S.R.1    San Martin, J.2    McClung, M.R.3
  • 27
    • 79955117784 scopus 로고    scopus 로고
    • Treatment with denosumab reduces the incidence of new vertebral and hip fractures in postmenopausal women at high risk
    • March 16, [Epub ahead of print]
    • Boonen S, Adachi JD, Man Z, et al. Treatment with denosumab reduces the incidence of new vertebral and hip fractures in postmenopausal women at high risk. J Clin Endocrinol Metab. March 16, 2011. [Epub ahead of print].
    • (2011) J Clin Endocrinol Metab
    • Boonen, S.1    Adachi, J.D.2    Man, Z.3
  • 28
    • 33845890326 scopus 로고    scopus 로고
    • Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-Term Extension (FLEX): A randomized trial
    • Black DM, Schwartz AV, Ensrud KE, et al. Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-Term Extension (FLEX): a randomized trial. JAMA. 2006;296(24):2927-2938.
    • (2006) JAMA , vol.296 , Issue.24 , pp. 2927-2938
    • Black, D.M.1    Schwartz, A.V.2    Ensrud, K.E.3
  • 29
    • 79953897155 scopus 로고    scopus 로고
    • Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass
    • Bone HG, Bolognese MA, Yuen CK, et al. Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass. J Clin Endocrinol Metab. 2011;96(4):972-980.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.4 , pp. 972-980
    • Bone, H.G.1    Bolognese, M.A.2    Yuen, C.K.3
  • 30
    • 78650314607 scopus 로고    scopus 로고
    • Comparison of the effect of denosumab and alendronate on bone mineral density and biochemical markers of bone turnover in postmenopausal women with low bone mass: A randomized, blinded, phase 3 trial
    • Brown JP, Prince RL, Deal C, et al. Comparison of the effect of denosumab and alendronate on bone mineral density and biochemical markers of bone turnover in postmenopausal women with low bone mass: A randomized, blinded, phase 3 trial. J Bone Miner Res. 2009;14:1-34.
    • (2009) J Bone Miner Res , vol.14 , pp. 1-34
    • Brown, J.P.1    Prince, R.L.2    Deal, C.3
  • 31
    • 0036284616 scopus 로고    scopus 로고
    • Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents
    • Hochberg MC, Greenspan S, Wasnich RD, Miller P, Thompson DE, Ross PD. Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab. 2002;87(4):1586-1592.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.4 , pp. 1586-1592
    • Hochberg, M.C.1    Greenspan, S.2    Wasnich, R.D.3    Miller, P.4    Thompson, D.E.5    Ross, P.D.6
  • 32
    • 79959495797 scopus 로고    scopus 로고
    • Bone turnover markers and bone mineral density response with risedronate therapy: Relationship with fracture risk and patient adherence
    • February 1, [Epub ahead of print]
    • Eastell R, Vrijens B, Cahall DL, Ringe JD, Garnero P, Watts NB. Bone turnover markers and bone mineral density response with risedronate therapy: Relationship with fracture risk and patient adherence. J Bone Miner Res. February 1, 2011. [Epub ahead of print].
    • (2011) J Bone Miner Res
    • Eastell, R.1    Vrijens, B.2    Cahall, D.L.3    Ringe, J.D.4    Garnero, P.5    Watts, N.B.6
  • 33
    • 11844252588 scopus 로고    scopus 로고
    • Risk of fracture after androgen deprivation for prostate cancer
    • Shahinian VB, Kuo YF, Freeman JL, Goodwin JS. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med. 2005;352(2):154-164.
    • (2005) N Engl J Med , vol.352 , Issue.2 , pp. 154-164
    • Shahinian, V.B.1    Kuo, Y.F.2    Freeman, J.L.3    Goodwin, J.S.4
  • 34
    • 47049120553 scopus 로고    scopus 로고
    • Survival following primary androgen deprivation therapy among men with localized prostate cancer
    • Lu-Yao GL, Albertsen PC, Moore DF, et al. Survival following primary androgen deprivation therapy among men with localized prostate cancer. JAMA. 2008;300(2):173-181.
    • (2008) JAMA , vol.300 , Issue.2 , pp. 173-181
    • Lu-Yao, G.L.1    Albertsen, P.C.2    Moore, D.F.3
  • 35
    • 78651390342 scopus 로고    scopus 로고
    • Management of osteoporosis in men on androgen deprivation therapy
    • Adler RA. Management of osteoporosis in men on androgen deprivation therapy. Maturitas. 2011;68(2):143-147.
    • (2011) Maturitas , vol.68 , Issue.2 , pp. 143-147
    • Adler, R.A.1
  • 36
    • 41549161181 scopus 로고    scopus 로고
    • Rehospitalization after hip fracture: Predictors and prognosis from a national veterans study
    • French DD, Bass E, Bradham DD, Campbell RR, Rubenstein LZ. Rehospitalization after hip fracture: Predictors and prognosis from a national veterans study. J Am Geriatr Soc. 2008;56(4):705-710.
    • (2008) J Am Geriatr Soc , vol.56 , Issue.4 , pp. 705-710
    • French, D.D.1    Bass, E.2    Bradham, D.D.3    Campbell, R.R.4    Rubenstein, L.Z.5
  • 37
    • 33947732766 scopus 로고    scopus 로고
    • Effect of onceweekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: A randomized trial
    • Greenspan SL, Nelson JB, Trump DL, Resnick NM. Effect of onceweekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: A randomized trial. Ann Intern Med. 2007;146(6):416-424.
    • (2007) Ann Intern Med , vol.146 , Issue.6 , pp. 416-424
    • Greenspan, S.L.1    Nelson, J.B.2    Trump, D.L.3    Resnick, N.M.4
  • 38
    • 78449282443 scopus 로고    scopus 로고
    • Androgen deprivation therapy in prostate cancer: Anticipated side-effects and their management
    • Kim HS, Freedland SJ. Androgen deprivation therapy in prostate cancer: Anticipated side-effects and their management. Curr Opin Support Palliat Care. 2010;4(3):147-152.
    • (2010) Curr Opin Support Palliat Care , vol.4 , Issue.3 , pp. 147-152
    • Kim, H.S.1    Freedland, S.J.2
  • 39
    • 34247640057 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer: New concepts and concerns
    • Smith MR. Androgen deprivation therapy for prostate cancer: New concepts and concerns. Curr Opin Endocrinol Diabetes Obes. 2007;14(3):247-254.
    • (2007) Curr Opin Endocrinol Diabetes Obes , vol.14 , Issue.3 , pp. 247-254
    • Smith, M.R.1
  • 40
    • 44449134102 scopus 로고    scopus 로고
    • Androgen deprivation therapy and risk for diabetes and cardiovascular disease in prostate cancer survivors
    • Smith MR. Androgen deprivation therapy and risk for diabetes and cardiovascular disease in prostate cancer survivors. Curr Urol Rep. 2008;9(3):197-202.
    • (2008) Curr Urol Rep , vol.9 , Issue.3 , pp. 197-202
    • Smith, M.R.1
  • 41
    • 69049105440 scopus 로고    scopus 로고
    • Denosumab in men receiving androgen-deprivation therapy for prostate cancer
    • Smith MR, Egerdie B, Hernandez Toriz N, et al. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med. 2009;361(8):745-755.
    • (2009) N Engl J Med , vol.361 , Issue.8 , pp. 745-755
    • Smith, M.R.1    Egerdie, B.2    Hernandez Toriz, N.3
  • 42
    • 30344468795 scopus 로고    scopus 로고
    • Prevalence of osteopenia and osteoporosis by central and peripheral bone mineral density in men with prostate cancer during androgen-deprivation therapy
    • Bruder JM, Ma JZ, Basler JW, Welch MD. Prevalence of osteopenia and osteoporosis by central and peripheral bone mineral density in men with prostate cancer during androgen-deprivation therapy. Urology. 2006;67(1):152-155.
    • (2006) Urology , vol.67 , Issue.1 , pp. 152-155
    • Bruder, J.M.1    Ma, J.Z.2    Basler, J.W.3    Welch, M.D.4
  • 43
    • 79953897155 scopus 로고    scopus 로고
    • Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass
    • Bone HG, Bolognese MA, Yuen CK, et al. Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass. J Clin Endocrinol Metab. 2011;96(4):972-980.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.4 , pp. 972-980
    • Bone, H.G.1    Bolognese, M.A.2    Yuen, C.K.3
  • 44
    • 79951581065 scopus 로고    scopus 로고
    • American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis
    • Grossman JM, Gordon R, Ranganath VK, et al. American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis. Arthritis Care Res. 2010;62(11):1515-1526.
    • (2010) Arthritis Care Res , vol.62 , Issue.11 , pp. 1515-1526
    • Grossman, J.M.1    Gordon, R.2    Ranganath, V.K.3
  • 46
    • 77951565454 scopus 로고    scopus 로고
    • Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates
    • Dore RK, Cohen SB, Lane NE, et al. Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates. Ann Rheum Dis. 2010;69(5):872-875.
    • (2010) Ann Rheum Dis , vol.69 , Issue.5 , pp. 872-875
    • Dore, R.K.1    Cohen, S.B.2    Lane, N.E.3
  • 47
    • 79551568488 scopus 로고    scopus 로고
    • Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study
    • Stopeck AT, Lipton A, Body JJ, et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study. J Clin Oncol. 2010;28(35):5132-5139.
    • (2010) J Clin Oncol , vol.28 , Issue.35 , pp. 5132-5139
    • Stopeck, A.T.1    Lipton, A.2    Body, J.J.3


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