A case of de novo secondary malignant giant-cell tumor of bone with loss of heterozygosity of p53 gene that transformed within a short-term follow-up

Pathology Research and Practice

Volumn 207, Issue 10, 2011, Pages 664-669

  Saito, Tsuyoshi ^a   Mitomi, Hiroyuki ^a   Suehara, Yoshiyuki ^a   Okubo, Taketo ^a   Torigoe, Tomoaki ^a   Takagi, Tatsuya ^a   Kaneko, Kazuo ^a   Yao, Takashi ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Giant cell tumor; Loss of heterozygosity; Malignant bone tumor; P53

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; BONE GRAFT; BONE TUMOR; CASE REPORT; CLINICAL FEATURE; CURETTAGE; FEMALE; FOLLOW UP; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GIANT CELL TUMOR; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALIGNANT TRANSFORMATION; MOLECULAR PATHOLOGY; OSTEOSYNTHESIS; OSTEOTOMY; RECURRENT CANCER; RETROSPECTIVE STUDY; STROMA CELL; SYSTEMIC THERAPY; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; BONE NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; DNA MUTATIONAL ANALYSIS; FEMALE; FOLLOW-UP STUDIES; GIANT CELL TUMOR OF BONE; HUMANS; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; LOSS OF HETEROZYGOSITY; MOLECULAR SEQUENCE DATA; NEOPLASM RECURRENCE, LOCAL; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 80755140467     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2011.07.009     Document Type: Article

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