Association study and expression analysis of porcine ESR1 as a candidate gene for boar fertility and sperm quality

Animal Reproduction Science

Volumn 128, Issue 1-4, 2011, Pages 11-21

  Gunawan, Asep ^a   Kaewmala, Kanokwan ^a   Uddin, Muhammad Jasim ^a   Cinar, Mehmet Ulas ^a   Tesfaye, Dawit ^a   Phatsara, Chirawath ^a,b   Tholen, Ernst ^a   Looft, Christian ^a   Schellander, Karl ^a  

^a UNIVERSITY OF BONN   (Germany)

^b CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Epididymis; Immunofluorescence; MRNA; Spermatogenesis; Spermatozoa

Indexed keywords

ESTROGEN RECEPTOR ALPHA; MESSENGER RNA;

ANIMAL; ARTICLE; FERTILITY; GENETIC POLYMORPHISM; GENETICS; MALE; MALE GENITAL SYSTEM; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; SPERMATOGENESIS; SPERMATOZOON; SWINE;

ANIMALS; ESTROGEN RECEPTOR ALPHA; FERTILITY; GENITALIA, MALE; MALE; POLYMORPHISM, GENETIC; PROTEIN TRANSPORT; RNA, MESSENGER; SPERMATOGENESIS; SPERMATOZOA; SWINE;

SUIDAE; SUS;

EID: 80655148972     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2011.08.008     Document Type: Article

References (47)

1. Aquila S., Sisci D., Gentile M., Middea E., Siciliano L., Ando S. Human-ejaculated spermatozoa contain active P450 aromatase. J. Clin. Endocrinol. Metab. 2002, 87:85-90.
2. Capon F., Allen M.H., Ameen M., Burden A.D., Tillman D., Barker J.N., Trembath R.C. A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups. Hum. Mol. Genet. 2004, 13:2361-2368.
3. Carreau S., Bourguiba S., Lambard S., Galeraud-Denis I., Genissel C., Levallet J. Reproductive system: aromatase and estrogens. Mol. Cel. Endocrinol. 2002, 193:137-143.
4. Clulow J., Jones R., Hansen L. Micropuncture and cannulation studies of fluid composition and transport in the ductuli efferentes testis of the rat:comparisons with the homologous metanephric proximal tubule. Exp. Physiol. 1994, 79:915-928.
5. Couse J., Korach K. Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr. Rev. 1999, 20:358-417.
6. Durkee T., Mueller M., Zinaman M. Identification of oestrogen receptor protein and messenger ribonucleic acid in human spermatozoa. Am. J. Obstet. Gynecol. 1998, 178:1288-1295.
7. Eddy E., Washburn T., Bunch D., Goulding E., Gladen B., Lubahn D., Korach K. Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 1996, 137:4796-4805.
8. Filippi S., Vannelli G.B., Granchi S., Luconi M., Crescioli C., Mancina R., Natali A., Brocchi S., Vignozzi L., Bencini E., Noci I., Ledda F., Forti G., Maggi M. Identification, localization and functional activity of oxytocin receptors in epididymis. Mol. Cel. Endocrinol. 2002, 193:89-100.
9. Fisher J., Millar M., Majdic G., Saunders P., Fraser H., Sharpe R. Immunolocalisation of oestrogen receptor 1 within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood. J. Endocrinol. 1997, 153:485-495.
10. Ganjam V., Amann R. Steroid content of fluids and sperm entering and leaving the bovine epididymis, in epididymal tissue, and in accessory sex gland secretions. Endocrinology 1976, 99:1618-1630.
11. Guarducci E., Nuti, Becherini L., Rotondi M., Balercia G., Forti G., Krausz C. Estrogen receptor 2 promoter polymorphism: stronger estrogen action is coupled with lower sperm count. Hum. Reprod. 2006, 21:994-1001.
12. Hejmej A., Gorazd M., Kosiniak-Kamysz K., Wisniewska B., Sadowska J., Bilinska B. Expression aromatase and androgen receptors in reproductive tissue of the stallion and a single cryptochid visualized by means of immunohistochemistry. Domest. Anim. Endricinol. 2005, 29:534-547.
13. Hess R., Carnes K. The role of oestrogen in testis and male reproductive tract: a review and species comparison. Anim. Reprod. 2003, 1:5-30.
14. Hess R., Gist D., Bunick D. Estrogen receptor (alpha and beta) expression in the excurrent ducts of the adult male rat reproductive tract. J. Androl. 1997, 18:602-611.
15. Iida K., Akashi H. A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes. Gene 2000, 261:93-102.
16. Janulis L., Hess R., Bunick D., Nitta H., Janssen S., Asawa Y., Bahr J. Mouse epididimal sperm containt active P450 aromatase which decrease as sperm traverse the epididymis. J. Androl. 1996, 17:111-116.
17. Jiang W., Le B. Structure and expression of the human MEP1A gene encoding the alpha subunit of metalloendopeptidase meprin A. Arch. Biochem. Biophys. 2000, 379:183-187.
18. Kaewmala K., Uddin M.J., Cinar M.U., Grosse-Brinkhaus C., Jonas E., Tesfaye D., Phatsara C., Tholen E., Looft C., Schellander K. Association study and expression analysis of CD9 as candidate gene for boar sperm quality and fertility traits. Anim. Reprod. Sci. 2011, 10.1016/j.anireprosci.2011.02.017.
19. Kuiper G., Enmark E., Puelto-Huiko M., Nilsson S., Gustafsson J. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:2925-2930.
20. Lazaros L.A., Xita N.V., Kaponis A.I., Zikopoulos K.A., Plachouras N.I., Georgiou I.A. Estrogen receptor alpha and beta polymorphisms are associated with semen quality. J. Androl. 2010, 31:291-298.
21. Lin C.L., Tholen E., Jennen D., Ponsuksili S., Schellander K., Wimmers K. Candidate gene markers for sperm quality and fertility of boar. Anim. Reprod. Sci. 2006, 92:349-363.
22. Liu G.Q., Zhu J.J., Wang Z.Y., Jiang X.P., Dafalla M.M. Analysis of sperm storage ability using duration of fertility in hens. Br. Poult. Sci. 2008, 49:770-775.
23. Lubahn D.B., Moyer J.S., Golding T.S. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:11162-11166.
24. MacCalman C.D., Blaschuk O. Gonadal steroids regulate N-cadherin mRNA levels in the mouse testis. Endocr. Rev. 1994, 2:157-163.
25. Montag M., Parrington J., Swann K., Lai F., Van der Ven H. Presence and localization of oscillin in human spermatozoa in relation to integrity of the sperm membrane. FEBS Lett. 1998, 423:357-361.
26. Mowa C.N., Iwanaga T. Expression of estrogen receptor-alpha and -beta mRNAs in the male reproductive system of the rat as revealed by in situ hybridization. J. Mol. Endocrinol. 2001, 26:165-174.
27. Munoz G., Ovio C., Estell J., Silio L., Fernadez A., Rodriguez C. Association with litter size of new polymorphism on ESR1 and ESR2 genes in a Chinese-European pig line. Genet. Sel. Evol. 2007, 39:195-206.
28. Nie R., Zhou Q., Jassin E., Saunders P., Hess R. Differential expression of oestrogen receptors alpha and beta in the reproductive tract of adult male dogs and cats. Biol. Reprod. 2002, 66:1161-1168.
29. Nijs M., Vanderzwalmen P., Vandamme G. Fertilizing ability of immotil spermatozoa after intracyctoplasmic sperm injection. Hum. Reprod. 1996, 11:2180-2185.
30. O'Donnell L., Robertson K.M., Jones M.E., Simpson E.R. Estrogen and spermatogenesis. Endocr. Rev. 2001, 22:289-318.
31. 2+ channel knockout mouse. Neuroscience 2004, 123:75-85.
32. Parlevliet J., Pearl C., Hess M., Famula T., Roser J. Immunolocalization of estrogen and androgen receptors and steroid concentrations in the stallion epididymis. Theriogenoloy 2006, 66:755-765.
33. Pearl C., Berger T., Roser J. Estrogen and androgen receptor expression in relation to steroids concentrations in adult boar epididymis. Domest. Anim. Endocrinol. 2007, 33:451-459.
34. Pelletier G., Labrie C., Labrie F. Localization of oestrogen receptor alpha, oestrogen receptor beta and androgen receptors in the rat reproductive organs. J. Endocrinol. 2000, 165:359-370.
35. Ramalho-Santos J., Schatten G., Moreno R. Control membrane fusion during spermiogenesis and the acrosome reaction. Biol. Reprod. 2002, 67:1043-1051.
36. Rozen S., Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 2000, 132:365-386.
37. Safarinejad M.R., Shafiei N., Safarinejad S. Association of polymorphisms in the estrogen receptors alpha, and beta (ESR1, ESR2) with the occurrence of male infertility and semen parameters. J. Steroid Biochem. Mol. Biol. 2010, 122:193-203.
38. Schleicher G., Drew U., Stumpt W., Sar M. Differential distribution of dihydrosterone and estrodial binding site in the epididymis of the mouse: an autoradiographic study. Histochemistry 1984, 1139-1147.
39. See M. Selection for AI stud traits. Proceedings of National Swine Improvement Federation 2000, 25.
40. Shayu D., Chennakesava C., Soundarajan R., Rao J. Effect of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey. Reprod. Biol. Endocrinol. 2004, 3:3-10.
41. Solakidi S., Psarra A., Nikolaropouluos S., Sekeris C. Estrogen receptor alpha and beta and androgen receptor (AR) in human sperm: localization of Estrogen beta and AR in mitochondria of the midpiece. Hum. Reprod. 2005, 20:3481-3487.
42. Stalhammar E., Janson L., Philipsson J. Genetic studies on fertility in AI bulls. II. Environmental and genetic effects on non-return rates of young bulls. Anim. Reprod. Sci. 1994, 34:193-207.
43. Suzuki Y., Sasagawa I., Itoh K., Ashida J., Muroya K., Ogata T. Estrogen receptor alpha gene polymorphism is associated with idiopathic azoospermia. Fertil. Steril. 2002, 78:1341-1343.
44. Syntin P., Dacheux F., Druart X., Gatti J., Okamura N., Dacheux J. Characterization and identification of proteins secreted in the various regions of the adult boar epididymis. Biol. Reprod. 1999, 55:956-974.
45. Wimmers K., Lin C., Tholen E., Jennen D., Schellander K., Ponsuksili S. Polymorphisms in candidate genes as markers for sperm quality and boar fertility. Anim. Genet. Sel. Evol. 2005, 36:152-155.
46. Xing Y., Ren J., Ren D., Guo Y., Wu Y., Yang G., Mao H., Brenig B., Huang L. A whole genome scanning for quantitative trait loci on traits related to sperm quality and ejaculation in pigs. Anim. Reprod. Sci. 2008, 114:210-2118.
47. Zhou Q., Nie R., Prins G., Saunders P., Katzenellenbogen B., Hess R. Localization of androgen and oestrogen receptors in adult male mouse reproductive tract. J. Androl. 2002, 23:870-881.