A mechanism of catalyzed GTP hydrolysis by Ras protein through magnesium ion

Chemical Physics Letters

Volumn 516, Issue 4-6, 2011, Pages 233-238

  Lu, Qiang ^a,e   Nassar, Nicolas ^b   Wang, Jin ^a,c,d  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Stony Brook University   (United States)

^d CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^e Shorter University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATPASES; CUT-OFF; GTP HYDROLYSIS; GTPASES; HUMAN CANCER; SIGNALING PATHWAYS; SIMULATION RESULT;

GROWTH KINETICS; MAGNESIUM; MANGANESE; MANGANESE COMPOUNDS; METAL IONS;

HYDROLYSIS;

EID: 80655132888     PISSN: 00092614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cplett.2011.09.071     Document Type: Article

References (35)

1. A.E. Karnoub, and R.A. Weinberg Nat. Rev. Mol. Cell Bio. 9 2008 517
2. M. Barbacid Annu. Rev. Biochem. 56 1987 779
3. C. Branden, and J. Tooze Introduction to Protein Structure second ed. 1998 Garland Publishing, Inc. New York
4. G.P. Li, and X.J.C. Zhang J. Mol. Bio. 340 2004 921
5. J. Ma, and M. Karplus Proc. Natl. Acad. Sci. USA 94 1997 11905
6. I.R. Vetter, and A. Wittinghofer Science 294 2001 1299
7. B. Ford, V. Hornak, H. Kleinman, and N. Nassar Structure 14 2006 427
8. A.A. Gorfe, B.J. Grant, and J.A. McCammon Structure 16 2008 885
9. S. Gras EMBO Rep. 8 2007 569
10. M.V. Milburn, L. Tong, A.M. Devos, A. Brunger, Z. Yamaizumi, S. Nishimura, and S.H. Kim Science 247 1990 939
11. L. Tong, A.M. Devos, M.V. Milburn, and S.H. Kim J. Mol. Biol. 217 1991 503
12. R.M. Immormino J. Mol. Biol. 388 2009 1033
13. E. Papagrigoriou et al., Crystal Structure of DiRas2. RCSB PDB () 2005, PDB ID: 2ERX, doi: 10.2210/pdb2ERX/pdb.
14. A. Turnbull et al., 2005. The crystal structure of human RERG in the GDP bound state. RCSB PDB () PDB ID: 2ATV, doi: 10.2210/pdb2ATV/pdb.
15. S. Pasqualato, and J. Cherfils Structure 13 2005 533
16. D.E. Coleman, and S.R. Sprang Biochemistry 37 1998 14376
17. A.T. Constantinescu, A. Rak, K. Alexandrov, H. Esters, R.S. Goody, and A.J. Scheldig Structure 10 2002 569
18. Y.J. Rao Chin. J. Struct. Chem. 25 2006 854
19. A. Turnbull et al., The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state. RCSB PDB (), 2006, PDB ID: 2FN4, doi: 10.2210/pdb2FN4/pdb.
20. E. Salah et al., The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state. RCSB PDB (), 2005, PDB ID: 2ERY, doi: 10.2210/pdb2ERY/pdb.
21. N. Nassar, K. Skowronek, Crystal structure of the GDP-bound form of the RasG60A mutant. RCSB PDB (), 2005, PDB ID: 1XJ0, doi: 10.2210/pdb1XJ0/pdb.
22. R. Elber Comp. Phys. Commun. 91 1995 159
23. G. Verkhivker, R. Elber, and Q.H. Gibson J. Am. Chem. Soc. 114 1992 7866
24. E.F. Pai, U. Krengel, G.A. Petsko, R.S. Goody, W. Kabsch, and A. Wittinghofer EMBO J. 9 1990 2351
25. G. Buhrman, G. Wink, and C. Mattos Structure 15 2007 1618
26. T. Tanaka, R.L. Williams, and T.H. Rabbitts EMBO J. 26 2007 3250
27. B.A. Fold, N. Nassar, Crystal structure of the GppNHp-bound form of the RasG60A mutant. RCSB PDB (), 2005, PDB ID: 1XCM, doi: 10.2210/pdb1XCM/pdb.
28. G.M. Torrie, and J.P. Valleau Chem. Phys. Lett. 28 1974 578
29. G.M. Torrie, and J.P. Valleau J. Comp. Phys. 23 1977 187
30. C.J. Der, T. Finkel, and G.M. Cooper Cell 44 1986 167
31. N.R. Voss, and M. Gerstein Nucl. Acids Res. 38 Suppl. 2010 W555
32. G.D. Markham, J.P. Glusker, and C.W. Bock J. Phys. Chem. B 106 2002 5118
33. M.J. Frisch Gaussian 98 1998 Gaussian, Inc. Pittsburgh, PA
34. S.J. Admiraal, and D. Herschlag Chem. Biol. 2 1995 729
35. Schweinsa J. Mol. Biol. 4 1997 847