The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase

Biochemical Pharmacology

Volumn 82, Issue 12, 2011, Pages 1853-1859

  Pedrolli, Danielle B ^a   Nakanishi, Shinobu ^a   Barile, Maria ^b   Mansurova, Madina ^c   Carmona, Eleonora C ^d   Lux, Andreas ^a   Gärtner, Wolfgang ^c   Mack, Matthias ^a  

^a MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b UNIVERSITY OF BARI   (Italy)

^c MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Antibiotics; Flavin analogs; Human FAD synthetase; Human flavokinase; Streptomyces davawensis

Indexed keywords

8 DEMETHYL 8 AMINO RIBOFLAVIN; 8 DEMETHYL 8 AMINO RIBOFLAVIN MONONUCLEOTIDE; ANTIBIOTIC AGENT; FLAVINE ADENINE DINUCLEOTIDE SYNTHETASE; QUERCETIN; RIBOFLAVIN KINASE; ROSEOFLAVIN; ROSEOFLAVIN MONONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES DAVAWENSIS;

ANTI-BACTERIAL AGENTS; CATALYTIC DOMAIN; DITHIONITE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEOTIDYLTRANSFERASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PICHIA; PROTEIN CONFORMATION; RIBOFLAVIN; STREPTOMYCES;

EID: 80555149405     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.08.029     Document Type: Article

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