Chronic oral exposure to Bisphenol a results in a nonmonotonic dose response in mammary carcinogenesis and metastasis in mmtv-erbb2 mice

Environmental Health Perspectives

Volumn 119, Issue 11, 2011, Pages 1604-1609

  Jenkins, Sarah ^a   Wang, Jun ^a   Eltoum, Isam ^b   Desmond, Renee ^b   Lamartiniere, Coral A ^a,b  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Apoptosis; Bisphenol A; BPA; Mammary gland; MMTV erbB2 mice; Oral exposure; Tumorigenesis

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DRINKING WATER; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; PROTEIN KINASE B; SOMATOMEDIN C RECEPTOR;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER SIZE; CELL PROLIFERATION; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LONG TERM EXPOSURE; MAMMARY GLAND; METASTASIS; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WILD TYPE; XENOBIOTIC METABOLISM;

ANIMALS; CARCINOGENS, ENVIRONMENTAL; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; PHENOLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1; TIME FACTORS;

MOUSE MAMMARY TUMOR VIRUS; MUS; MUS MUSCULUS;

EID: 80455173409     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1103850     Document Type: Article

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