Effects of rapamycin on expression of Bcl-2 and bax in human lens epithelial cells and cell cycle in rats

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 31, Issue 4, 2011, Pages 555-559

  Wang, Zhi ^a   Wang, Ziyi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Cell cycle; Human lens epithelial cell; Rapamycin

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; RAPAMYCIN;

ANIMAL; ARTICLE; CELL CYCLE; DRUG EFFECT; EPITHELIUM CELL; EYE; GENE EXPRESSION; GENETICS; HUMAN; RAT; TUMOR CELL LINE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL LINE, TUMOR; EPITHELIAL CELLS; EYE; GENE EXPRESSION; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SIROLIMUS;

EID: 80455164783     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-011-0489-x     Document Type: Article

References (19)

1. Andey SK, Apple DJ, Werner L, et al. Posterior capsule opacification: a review of the aetiopathogenesis, experimental and clinical studies and factors for prevention. Indian J Ophthalmol, 2004,2(2):99-112 (Pubitemid 38915497)
2. Del Vecchio PJ, Bizios R, Holleran LA, et al. Inhibition of human scleral fibroblast proliferation with heparin. Invest Ophthalmol Vis Sci, 1988,29(8):1272-1276
3. Liu GF, Su GF, Zhou HY. Lens epithelial cells apoptosis and apoptosis-related gene expression in senile cataract. Zhongguo Laonianxue Zazhi (Chinese), 2007,27(12): 1186-1188
4. Fan W, Ji X, Yu CT. Relationship between lens epithelial cells apoptosis, bcl-2 and bax expression with age-related cataract. Yanshi Guangxue Zazhi (Chinese), 2003,5(2): 49-51
5. Weng JN, Zhang HR. The characteristics of bcl-2 and PCNA expression in the lens epithelium of human being. Zhonghua Yanke Zazhi (Chinese), 2001,37(5):197-198
6. Wang JB, Yang JY, Chen W, et al. Effect of rapamycin on proliferation of rat aortic smooth muscle cells. Zhongshan Daxue Xuebao (Xixue Kexue Ban) (Chinese), 2006,27(3):255-257
7. Zhang LF, Xiao F, Li J, et al. Local applied slow-releasing rapamycin inhibits neointima hyperplasia in vein graft. Zhonghua Xie Xue Za Zhi (Chinese), 2006,24(6):1706-1709 (Pubitemid 44322318)
8. Yao MJ. Progress in the treatment of after-cataract. Dangdai Yixue (Chinese), 2008,24(12):14-15
9. Wang Z, Shi QQ, Chen W, et al. Effects of NO-fluvastain on proliferation of in vitro cultured human lens epithelial cells. Yanke Yanjiu (Chinese), 2008,26(4):276-279 (Pubitemid 351669048)
10. Lai XN, Li RZ. Advance in the drug prophylaxis of posterior cataract. Zhongguo Redai Yixue (Chinese), 2008,8(1):140-142
11. Ma L, Wan YS, Chen DS. Clinical application of tacrolimus. Yaowu Liuxingbing Zazhi (Chinese), 2008,17(1): 8-10
12. Wang XH, Shen Y, Xia WL, et al. Antiproliferative effects of rapamycin in combination with FTY720 on pancreatic cancer cells in vitro. Zhonghua Yizhi Zazhi (Chinese), 2009,3(1):39-44
13. Yin Y J, Li J, Tang Y, et al. Immune reguatory effects of mesenchymal stem cells combined with rapamycin on the splenic lymphocytes in allogenic mice. Shandong Daxue Xuebao (Yixue Ban) (Chinese), 2009,47(4): 58-62
14. Allo R, Padurean A, Jayaraman T, et al. Inhibition of intimal thickening after balloon angioplasty in porcine coronary arteries by targeting regulators of the cell cycle. Circulation, 1999,99(16):2164-2170 (Pubitemid 29196802)
15. Zhao XR, Yang W. Effect of rapamycin applied locally in corneal neovascularization of rabbit after alkali burning. Yan Waishang Zhiyebing Zazhi (Chinese), 2009,31(6): 401-404
16. Yang BZ, Li SZ. Uveitis. Beijing: People's Medical Publishing House, 1998:173-174
17. Deshpande S, Zheng M, Lee S, et al. Bystander activation involving T lymphocytes in herpetic stromal keratitis. J Immunol, 2001,167(5):2902-2910 (Pubitemid 32768925)
18. Zhao J, Cai KL. Effects of rapamycin on regeneration of cultured rabbit lens epithelial cells. Yanshi Guangxue Zazhi (Chinese), 2007,1(1):37-39
19. Abraham RT, Wiederrecht GJ. Immunopharmacology of rapamycin. Ann Rev Immunol, 1996,14(1):483-510. (Pubitemid 26130192)