Fetal microchimerism and swomen's health: A new paradigm

Biological Research for Nursing

Volumn 13, Issue 4, 2011, Pages 346-350

  Groër, Maureen W ^a   Manion, Maura ^a   Szekeres, Charles ^b   El Badri, Nagwa S ^b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

healing; hematopoietic stem cells; microchimerism; women's health

Indexed keywords

CHIMERA; FEMALE; FETUS; HUMAN; IMMUNOLOGICAL TOLERANCE; PREGNANCY; REVIEW; WOMEN'S HEALTH;

CHIMERISM; FEMALE; FETUS; HUMANS; IMMUNE TOLERANCE; PREGNANCY; WOMEN'S HEALTH;

EID: 80455143318     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800410385840     Document Type: Article

References (36)

1. Ariga H.,Ohto H.,Busch M. P.,Imamura S.,Watson R.,Reed W.,Lee T. H.Kinetics of fetal cellular and cell-free fetal DNA in the maternal circulation during and after pregnancy: Implications for non-invasive prenatal diagnosis.Transfusion. 2001;41:1524-1530.
2. Bianchi D.Fetomaternal cell trafficking: A story that begins with prenatal diagnosis and may end with stem cell therapy.Journal of Pediatric Surgery. 2007;42:12-18.
3. Bianchi D. W.,Farina A.,Weber W.,Delli-Bovi L. C.,Deriso M.,Williams J. M.,Klinger K.Significant fetal-maternal hemorrhage after termination of pregnancy: Implications for development of fetal cell microchimerism.American Journal of Obstetrics and Gynecology. 2001;184:703-706.
4. Bianchi D.,Zickwolf G.,Weil G.,Sylvester S.,DeMaria M.Male fetal progenitor cells persist in maternal blood for as long as 27 years.Proceedings of the National Academy of Science USA. 1996;93:705-708.
5. Burlingham W. J.,Goulmy E.Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigens.Human Immunology. 2008;69:728-731.
6. Durkin E.,Jones K.,Rajesh D.,Shaaban A.Early chimerism threshold predicts sustained engraftment and NK cell tolerance in prenatal allogeneic chimeras.Blood. 2008;112:5245-5253.
7. Evans P. C.,Lambert N.,Maloney S.,Furst D.,Moore J.,Nelson J.Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma.Blood. 1999;93:2033-2037.
8. Fugazzola L.,Cirello V.,Beck-Peccoz P.Fetal cell microchimerism in human cancers.Cancer Letters. 2010;287:136-141.
9. Fujiki Y.,Johnson K.,Tighiouart H.,Peter I.,Bianchi D.Fetomaternal trafficking in the mouse increases as delivery approaches and is highest in the maternal lung.Biology of Reproduction. 2008;79:841-848.
10. Gadi V. K.,Nelson J. L.Fetal microchimerism in women with breast cancer.Cancer Research, Human Immunology. 2007;67:9035-9038.
11. Groër M.,Davis M.,Smith K.,Casey K.,Kramer V.,Bukovsky E.Immunity, inflammation and infection in post-partum breast and formula feeders.American Journal of Reproductive Immunology. 2005;54:222-231.
12. Groër M.,El-Badri N.,Djeu J.,VanEopel J.Suppression of natural killer cell cytotoxicity in postpartum women.American Journal of Reproductive Immunology. 2009;63:209-213.
13. Ichinohe T.,Teshima T.,Matsuoka K.,Maruya E.,Saji H.Fetal-maternal microchimerism: Impact on hematopoietic stem cell-transplantation.Current Opinions in Immunology. 2005;17:546-552.
14. Johnson K.,Bianchi D.Fetal cells in maternal tissue following pregnancy: What are the consequences?.Human Reproduction. 2004;10:497-502.
15. Johnson K.,Samura O.,Nelson J.,McDonnell W.,Bianchi D.Significant fetal cell microchimerism in a nontransfused woman with hepatitis C: Evidence of long-term survival and expansion.Hepatology. 2002;36:1295-1297.
16. Khosrotehrani K.,Johnson K.,Lau J.,Dupuy A. Cha, D.,Bianchi D.The influence of fetal loss on the presence of fetal cell microchimerism.Arthritis and Rheumatism. 2003;48:3237-3241.
17. Khosrotehrani K.,Johnson K. L.,Cha D. H.,Salomon R. N.,Bianchi D. W.Transfer of fetal cells with multilineage potential to maternal tissue.Journal of the American Medical Association. 2004;292:75-80.
18. Khosrotehrani K.,Bianchi D.Multilineage potential of fetal cells in maternal tissue: A legacy in reverse.Journal of Cell Science. 2005;118:1559-1563.
19. Klintschar M.,Immel U.,Kehlen A.,Schwaiger P.,Mustafa T.,Mannweiler S.,Hoang-Vu C.Fetal microchimerism in Hashimoto's thyroiditis: A quantitative approach.European Journal of Endocrinology. 2006;154:237-241.
20. Kuroki M.,Okayama A.,Nakamura S.,Sasaki T.,Murai K.,Shiba R.,Tsubouchi H.Detection of maternal-fetal microchimerism in the inflammatory lesions of patients with Sjogren's syndrome.Annals of the Rheumatic Diseases. 2002;61:1041-1046.
21. Lambert N.,Lo Y.,Erickson T.,Tylee T.,Guthrie K.,Furst D.,Nelson J.Male microchimerism in healthy women and women with scleroderma: Cells or circulating DNA? A quantitative answer.Blood. 2002;100:2845-2851.
22. Le Maoult J.,Krawice-Radanne I.,Dausset J.,Carosella E.HLA-G1expressing antigen-presenting cells induce immunosuppressive CD4+ T cells.Proceedings of the National Academy of Science USA. 2004;101:7064-7069.
23. Lissauer D.,Piper K. P.,Moss P. A.,Kilby M.Persistence of fetal cells in the mother: Friend or foe?.British Journal of Obstetrics and Gynecology. 2007;114:1321-1325.
24. Medawar P.Symposia of the society for experimental biology: Vol. 7. Evolution. Brown R.Danielli J. F., ed. New York, NY: Academic Press; 1953:320-328.
25. Miles C.,Schaubel D.,Liu D.,Port F.,Rao P.The role of donor-recipient relationship in long-term outcomes of living donor renal transplantation.Transplantation. 2008;85:1483-1488.
26. Mold J.,Michaelsson J.,Burt T.,Muench M.,Beckerman K.,Busch M.,McCune J.Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.Science. 2008;322:1562-1565.
27. Nelson J.Maternal-fetal immunology and autoimmune disease: Is some autoimmune disease auto-alloimmune or allo-autoimmune?.Arthritis and Rheumatology. 1996;39:191-194.
28. Nelson J.,Furst D.,Maloney S.,Gooley T.,Evans P.,Smith A.,Bianchi D.Microchimerism and HLA-compatible relationships of pregnancy in scleroderma.Lancet. 1998;351:559-562.
29. Nelson J.Microchimerism: Expanding new horizon in human health or incidental remnant of pregnancy?.Lancet. 2001;358:2011-2012.
30. O'Donoghue K.,Sultan H.,Al-Allaf F.,Anderson J.,Wyatt-Ashmead J.,Fisk N.Microchimeric fetal cells cluster at sites of tissue injury in lung decades after pregnancy.Reproduction Biomedicine Online. 2008;16:382-390.
31. Piper K.,McLarnon A.,Arrazi J.,Horlock C.,Ainsworth J.,Kilby M.,Moss P.Functional HY-specific CD8+ T cells are found in a high proportion of women following pregnancy with a male fetus.Biological Reproduction. 2007;76:96-101.
32. Rak J. M.,Maestroni L.,Balandraud N.,Guis S.,Boudinet H.,Guzianm M.,Lambert N.Transfer of the shared epitope through microchimerism in women with rheumatoid arthritis.Arthritis and Rheumatism. 2009;60:73-80.
33. Renne C.,Ramos Lopez E.,Steimle-Grauer S.,Ziolkowski P.,Pani M.,Luther C.,Badenhoop K.Thyroid fetal male microchimerism in mother with thyroid disorder: Presence of Y-chromosomal immunofluorescence in thyroid-infiltrating lymphocytes is more prevalent in Hashimoto's thyroiditis and Graves' disease than in follicular adenomas.Journal of Clinical Endocrinology and Metabolism. 2004;89:5810-5814.
34. Shao L.,Jacobs A. R.,Johnson V. V.,Mayer L.Activation of CD8+ regulatory T cells by human placental trophoblasts.Journal of Immunology. 2005;174:7539-7547.
35. Skuladottir H.,Olsen J.Can reproductive pattern explain better survival of women with lung cancer?.Acta Oncologia. 2006;45:47-53.
36. Srivatsa B.,Srivatsa S.,Johnson K.,Samura O.,Lee S.,Bianchi D.Microchimerism of presumed fetal origin in thyroid specimens from women: A case-control study.Lancet. 2001;358:2034-2038.