Changes in morphology and optical properties of sclera and choroidal layers due to hyperosmotic agent

Journal of Biomedical Optics

Volumn 16, Issue 7, 2011, Pages

  Zaman, Raiyan T ^a   Rajaram, Narasimhan ^b   Nichols, Brandon S ^a   Rylander III, Henry G ^a   Wang, Tianyi ^a   Tunnell, James W ^a   Welch, Ashley J ^a  

^a The University of Texas at Austin   (United States)

^b Duke University   (United States)

Author keywords

Absorption coefficient; Diffuse optical spectroscopy; Hyperosmotic agents; Linear probe; Optical clearing; Optical properties; Reduced scattering coefficient; Sclera

Indexed keywords

ABSORPTION COEFFICIENTS; DIFFUSE OPTICAL SPECTROSCOPY; HYPEROSMOTIC AGENTS; LINEAR-PROBE; OPTICAL CLEARING; REDUCED SCATTERING COEFFICIENTS; SCLERA;

ABSORPTION; DIRECT INJECTION; GLYCEROL; SCATTERING; SPECTRUM ANALYSIS; TISSUE;

OPTICAL PROPERTIES;

ORYCTOLAGUS CUNICULUS;

GLYCEROL; MELANIN; OXYGEN;

ANIMAL; ANIMAL MODEL; ARTICLE; BLOOD; BLOOD VOLUME; CHOROID; DIAGNOSTIC IMAGING; DRUG EFFECT; EVALUATION; FEMALE; HISTOLOGY; IMAGE QUALITY; LIGHT; LIGHT RELATED PHENOMENA; METABOLISM; METHODOLOGY; OSMOLARITY; RABBIT; RADIATION SCATTERING; REGRESSION ANALYSIS; SCLERA; SPECTROSCOPY; STATISTICS; VASCULARIZATION; VISUAL SYSTEM EXAMINATION;

ANIMALS; BLOOD VOLUME; CHOROID; DIAGNOSTIC IMAGING; DIAGNOSTIC TECHNIQUES, OPHTHALMOLOGICAL; FEMALE; GLYCEROL; LIGHT; MELANINS; MODELS, ANIMAL; OPTICAL PHENOMENA; OSMOLAR CONCENTRATION; OXYGEN; PHANTOMS, IMAGING; RABBITS; REGRESSION ANALYSIS; SCATTERING, RADIATION; SCLERA; SPECTRUM ANALYSIS;

EID: 80455141520     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3599985     Document Type: Article

References (47)

1. V. V. Bakutkin, I. L. Maksimova, T. N. Semyonova, V. V. Tuchin, and I. L. Kon, "Controlling of optical properties of sclera," Proc. SPIE 2393, 137-141 (1995).
2. V. V. Tuchin, I. L. Maksimova, D. A. Zimnyahkov, I. L. Kon, A. K. Mavlutov, and A. A. Mishin, "Light propagation in tissues with controlled optical properties," Proc. SPIE 2925, 118-142 (1996).
3. V. V. Tuchin, I. L. Maksimova, D. A. Zimnyakov, I. L. Kon, A. K. Mavlutov, and A. A. Mishin, "Light propagation in tissues with controlled optical properties," J. Biomed. Opt. 2, 401-417 (1997). (Pubitemid 127663504)
4. V. V. Tuchin, Optical Clearing of Tissues and Blood, Monograph Vol. PM 154, Chapt. 2, pp. 23-58 and subsection 8.3, pp. 188-191, SPIE Press, Bellingham, WA (2006).
5. A. N. Bashkatov, V. V. Tuchin, E. A. Genina, Y. P. Sinichkin, N. A. Lakodina, and V. I. Kochubey, "The human sclera dynamic spectra: in vitro and in vivo measurements," Proc. SPIE 3591, 311-319 (1999).
6. V.V. Tuchin, J. Culver, C. Cheung, S. A. Tatarkova,M.A.DellaVecchia, D. Zimnyakov, A. Chaussky, A. G. Yodh, and B. Chance, "Refractive indexmatching of tissue components as a newtechnology for correlation and diffusing-photon spectroscopy and imaging," Proc. SPIE 3598, 111-120 (1999).
7. V. V. Tuchin, "Coherent soptical techniques for the analysis of tissue structure and dynamics," J. Biomed. Opt. 4(1), 106-124 (1999). (Pubitemid 129694557)
8. Z. S. Sacks, R. M. Kurtz, T. Juhasz, and G. A. Mourau, "High precision subsurface photodisruption in human sclera," J. Biomed. Opt. 7(3), 442-450 (2002).
9. E. A. Genina, A. N. Bashkatov, Yu. P. Sinichkin, and V. V. Tuchin, "Optical clearing of the eye sclera in vivo caused by glucose," Quantum Electron. 36(12), 1119-1124 (2006). (Pubitemid 46549400)
10. M. G. Ghosn, E. F. Carbajal, N. Befrui, V. V. Tuchin, and K. V. Larin, "Differential permeability rate and percent clearing of glucose in different regions in rabbit sclera," J. Biomed. Opt. 13, 021110 (2008).
11. G. Vargas, E. K. Chan, J. K. Barton, H. G. Rylander III, and A. J.Welch, "Use of an agent to reduce scattering in skin," Lasers Surg. Med. 24, 133-141 (1999). (Pubitemid 29133814)
12. G. Vargas, K. F. Chan, S. L. Thomsen, and A. J. Welch, "Use of osmotically active agents to alter optical properties of tissue: effects on the detected fluorescence signal measured through skin," Lasers Surg. Med. 29, 213-220 (2001). (Pubitemid 32946193)
13. G. Vargas, "Reduction of light scattering in biological tissue: implications for optical diagnostics and therapeutics," Doctoral Dissertation, The University of Texas at Austin (2001).
14. K. P. Boergen, R. Birngruber, V. P. Gabel, and F. Hillenkamp, "Experimental studies on controlled closure of small vessels by laser irradiation," Lasers Surg. Med. Biol. Proc. Berlin 5, 15.1-15.9 (1977).
15. R. T. Zaman, A. B. Parthasarathy, G. Vargas, B. Chen, A. K. Dunn, H. G. Rylander III, and A. J. Welch, "Perfusion in hamster skin treated with glycerol," Lasers Surg. Med. 41, 492-503 (2009).
16. N. Rajaram, T. H. Nguyen, and J. W. Tunnell, "Lookup table-based inverse model for determining optical properties of turbid media," J. Biomed. Opt. 13(5), 050501 (2008).
17. J. R. Mourant, T. Fuselier, J. Boyer, T. M. Johnson, and I. J. Bigio, "Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms," Appl. Opt. 36(4), 949-957 (1997). (Pubitemid 127638552)
18. J. C. Finlay and T. H. Foster, "Effect of pigment packaging on diffuse reflectance spectroscopy of samples containing red blood cells," Opt. Lett. 29(9), 965-967 (2004).
19. R. L. vanVeen,W.Verkruysse andH. J. Sterenborg, "Diffuse-reflectance spectroscopy from 500 to 1060 nm by correction for inhomogeneously distributed absorbers," Opt. Lett. 27(4), 246-248 (2002). (Pubitemid 34618015)
20. L. Svaasand, E. Fiskerstrand, G. Kopstad, L. Norvang, E. Svaasand, J. Nelson, and M. Berns, "Therapeutic response during pulsed laser treatment of port-wine stains: dependence on vessel diameter and depth in dermis," Lasers Med. Sci. 10(4), 235-243 (1995). (Pubitemid 26245480)
21. G. Vargas, A. Readinger, S. S. Dozier and A. J.Welch, "Morphological changes in blood vessels produced by hyper osmotic agents and measured by optical coherence tomography," Photochem. Photobiol. 77(5), 541-549 (2003).
22. R. W. Stephenson, Anatomy, Physiology and Optics of the Eye: A Textbook for Orthoptic Students, Kimpton Publishers, London (1973).
23. S. C. Nemeth, Ocular Anatomy and Physiology, Slack Inc. Publishers, Thorofare, NJ (2007).
24. Y. Feng and T. L. Simpson, "Corneal, limbal, and conjunctival epithelial thickness from optical coherence tomography," Optom. Vision Sci. 85(9), 880-883 (2008).
25. S. S. Hayreh, "Segmental nature of the choroidal vasculature," Br. J. Ophthalmol. 59(11), 631-648 (1975).
26. A. R. Young, "Chromophores in human skin," Phys. Med. Biol. 42, 789-802 (1997). (Pubitemid 27263500)
27. R. T. Zaman, P. Diagaradjane, J. C.Wang, J. Swartz, N. Rajaram, K. L. Gill-Sharp, S. H. Cho, H. G. Rylander, D. J. Payne, S. Krishnan, and J. W. Tunnell, "In vivo detection of gold nanoshells in tumors using diffuse optical spectroscopy," IEEE J. Sel. Top. Quantum Electron. 13(6), 1715-1720 (2007).
28. E. K. Chan, B. Sorg, D. Protsenko, M. O'Neil, M. Motamedi, and A. J. Welch, "Effects on compression on soft tissue optical properties," IEEE J. Sel. Top. Quantum Electron. 2(4), 943-950 (1996). (Pubitemid 126543835)
29. T. J. Farrell, M. S. Patterson, and B.Wilson, "A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo," Med. Phys. 19, 879-888 (1992).
30. A. Kienle and M. S. Patterson, "Improved solutions of the steadystate and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium," J. Opt. Soc. Am. A 14, 246-254 (1997). (Pubitemid 127573821)
31. N. Rajaram, A. Gopal, X. J. Zhang, and J. W. Tunnell, "Experimental validation of the effects of microvasculature pigment packaging on in vivo diffuse reflectance spectroscopy," Lasers Surg. Med. 42(7), 680- 688 (2010).
32. A. J. Welch and M. J. Gemert, Optical-Thermal Response of Laser-Irradiated Tissue, Appendix to Chapt. 8, Plenum, New York (1995).
33. S. Prahl, "Tabulated molar extinction coefficient for hemoglobin inwater," http://omlc.ogi.edu/spectra/hemoglobin/index.html, accessed 7/24/09.
34. B. T. West, K. B. Welch, and A. T. Galecki, Linear Mixed Models: A Practical Guide Using Statistical Software, Chapman and Hall, London (2007).
35. C. R. Ethier, M. Johnson, and J. Ruberti, "Ocular biomechanics and biotransport," Annu. Rev. Biomed. Eng. 6, 249-273 (2004). (Pubitemid 39209499)
36. M. G. Ghosn,V.V. Tuchin, and K.V. Larin, "Depth-resolved monitoring of glucose diffusion in tissues by using optical coherence tomography," Opt. Lett. 31(15), 2314-2316 (2006). (Pubitemid 44391868)
37. J. W. Kiel, "Endothelin modulation of choroidal blood flow in the rabbit," Exp. Eye Res. 71, 543-550 (2000). (Pubitemid 32002240)
38. S. Dallinger, G. T. Dorner, R. Wenzel, U. Graselli, O. Findl, H. G. Eichler, M. Wolzt, and L. Schmetterer, "Endothelin-1 contributes to hyperoxia-induced vasoconstriction in the human retina," Invest. Ophthalmol. Visual Sci. 41, 864-869 (2000). (Pubitemid 30158900)
39. Y. Zhu, T. S. Park, and J. M. Gidday, "Mechanisms of hyperoxiainduced reductions in retinal blood flow in newborn pig," Exp. Eye Res. 67, 357-369 (1998). (Pubitemid 28483235)
40. C. Takagi, G. L. King, H. Takagi, Y. W. Lin, A. C. Clermont, and S. E. Bursell, "Endothelin-1 action via endothelin receptors is a primary mechanism modulating retinal circulatory response to hyperoxia," Invest. Ophthalmol. Visual Sci. 37(10), 2099-2109 (1996). (Pubitemid 26321703)
41. K. Nishimura, C. E. Riva, S. Harino, P. Reinach, S. D. Cranstoun, and S. Mita, "Effects of endothelin-1 on optic nerve head blood flow in cats," J. Ocul. Pharmacol. Ther. 12, 75-83 (1996). (Pubitemid 26068319)
42. J. W. Kiel, "Endothelin modulation of choroidal blood flow in the rabbit," Exp. Eye Res. 71, 543-550 (2000). (Pubitemid 32002240)
43. R. F. Brubaker, "Measurement of aqueous flow by fluorophotometry, " The Glaucomas, pp. 337-344, Mosby, St. Louis (1989).
44. H. Ninomiya and T. Inomata, "Mirovascular anatomy of the pig eye: scanning electron microscopy of vascular corrosion casts," J. Vet. Med. Sci. 68(11), 1149-1154 (2006). (Pubitemid 44893701)
45. W. Verkruyssa, M. Khan, B. Choi, L. O. Svaasand, and S. J. Nelson, "Measuring the effects of topically applied skin optical clearing agents and modeling the effects and consequences for laser therapies," Proc. SPIE 5695, 278-287 (2005). (Pubitemid 41091294)
46. J. B. Walter and M. S. Israel, The Inflammatory Reaction In General Pathology, Chapt. 6, Churchill Livingston, London (1974).
47. L. M. Wahl and S. M. Wahl, Inflammation in Wound Healing. Biochemical and Clinical Aspects, pp. 40-53, Saunders, Philadelphia (1992).