Cyclodextrin-containing polycations for nucleic acid delivery

Cold Spring Harbor Protocols

Volumn 6, Issue 11, 2011, Pages 1319-1322

  Heidel, Jeremy D ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA CYCLODEXTRIN; CELL SURFACE RECEPTOR; CYCLODEXTRIN CONTAINING POLYCATION; DNA; DNAZYME; LIGAND; NUCLEIC ACID; PLASMID DNA; POLYCATION; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; SMALL INTERFERING RNA; TRANSFERRIN; UNCLASSIFIED DRUG; CYCLODEXTRIN; DEOXYRIBOZYME; POLYAMINE; POLYCATIONS;

ARTICLE; CELL CULTURE; CELL TYPE; COMPLEX FORMATION; GENE TARGETING; IMMUNOGENICITY; IN VIVO STUDY; NONVIRAL GENE DELIVERY SYSTEM; POLYMER NUCLEIC ACID COMPLEX; POLYPLEX; PROTEIN EXPRESSION; TOXICITY; GENETIC TRANSFECTION; METABOLISM; METHODOLOGY; PLASMID;

CELLS, CULTURED; CYCLODEXTRINS; DNA, CATALYTIC; PLASMIDS; POLYAMINES; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 80455129749     PISSN: None     EISSN: 15596095     Source Type: Journal    
DOI: 10.1101/pdb.top066639     Document Type: Article

References (15)

1. Bellocq NC, Pun SH, Jensen GS, Davis ME. 2003. Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 14: 1122-1132.
2. Davis ME, Pun SH, Bellocq NC, Reineke TM, Popielarski SR, Mishra S, Heidel JD. 2004. Self-assembling nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers. Curr Med Chem 11: 1241-1253.
3. Gonzalez H, Hwang SJ, Davis ME. 1999. New class of polymers for the delivery of macromolecular therapeutics. Bioconjug Chem 10: 1068-1074.
4. Heidel JD. 2005. "Targeted, systemic non-viral delivery of small interfering RNA in vivo." PhD thesis, California Institute of Technology, Pasadena.
5. Heidel JD. 2011. In vitro transfection using cyclodextrin-containing polycations. Cold Spring Harb Protoc doi: 10.1101/pdb.prot066647.
6. Heidel JD. 2011b. In vivo transfection using cyclodextrin-containing polycations. Cold Spring Harb Protoc doi: 10.1101/pdb.prot066654.
7. Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ. 2005. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res 65: 8984-8992.
8. Hwang SJ. 2001. "Rational design of a new class of cyclodextrin-containing polymers for gene delivery." PhD thesis, California Institute of Technology, Pasadena.
9. Hwang SJ, Bellocq NC, Davis ME. 2001. Effects of structure of β-cyclodextrin- containing polymers on gene delivery. Bioconjug Chem 12: 280-290.
10. Kulkarni RP, Mishra S, Fraser SE, Davis ME. 2005. Single cell kinetics of intracellular, nonviral, nucleic acid delivery vehicle acidification and trafficking. Bioconjug Chem 16: 986-994.
11. Popielarski SR, Mishra S, Davis ME. 2003. Structural effects of carbohydratecontaining polycations on gene delivery. 3. Cyclodextrin type and functionalization. Bioconjug Chem 14: 672-678.
12. Pun SH, Davis ME. 2002. Development of a nonviral gene delivery vehicle for systemic application. Bioconjug Chem 13: 630-639.
13. Pun SH, Tack F, Bellocq NC, Cheng J, Grubbs BH, Jensen GS, Davis ME, Brewster M, Janicot M, Janssens B, et al. 2004. Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles. Cancer Biol Ther 3: 641-650.
14. Reineke TM, Davis ME. 2003. Structural effects of carbohydrate-containing polycations on gene delivery. 1. Carbohydrate size and its distance from charge centers. Bioconjug Chem 14: 247-254.
15. Reineke TM, Davis ME. 2003. Structural effects of carbohydratecontaining polycations on gene delivery. 2. Charge center type. Bioconjug Chem 14: 255-261.