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Volumn 4, Issue SPEC. ISSUE 1, 2011, Pages 41-44

Accumulation of AGEs and VEGF in eyes of SDT rats

Author keywords

Advanced glycation end products (AGES); Diabetes; Diabetic retinopathy; Vascular endothelial growth factor (VEGF)

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; CARBOHYDRATE DERIVATIVE; GLUCOSE; PENTOSIDINE; PYRRALINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 80455125722     PISSN: None     EISSN: 18765246     Source Type: Journal    
DOI: 10.2174/1876524601104010041     Document Type: Article
Times cited : (1)

References (32)
  • 1
    • 0023181551 scopus 로고
    • Epidemiology of eye disease in the elderly
    • Hyman L. Epidemiology of eye disease in the elderly. Eye 1987; 1 (Pt 2): 330-41.
    • (1987) Eye , vol.1 , Issue.PART 2 , pp. 330-341
    • Hyman, L.1
  • 2
    • 0344923801 scopus 로고    scopus 로고
    • Blindness incidence in Germany. A population-based study from Wurttemberg-Hohenzollern
    • Krumpaszky HG, Ludtke R, Mickler A, Klauss V, Selbmann HK. Blindness incidence in Germany. A population-based study from Wurttemberg-Hohenzollern. Ophthalmologica 1999; 213: 176-82.
    • (1999) Ophthalmologica , vol.213 , pp. 176-182
    • Krumpaszky, H.G.1    Ludtke, R.2    Mickler, A.3    Klauss, V.4    Selbmann, H.K.5
  • 3
    • 0036291931 scopus 로고    scopus 로고
    • Visual impairment and blindness in Europe and their prevention
    • Kocur I, Resnikoff S. Visual impairment and blindness in Europe and their prevention. Br J Ophthalmol 2002; 86: 716-22.
    • (2002) Br J Ophthalmol , vol.86 , pp. 716-722
    • Kocur, I.1    Resnikoff, S.2
  • 4
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994; 331: 1480-7.
    • (1994) N Engl J Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 5
    • 0028123090 scopus 로고
    • Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
    • Adamis AP, Miller JW, Bernal MT, et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 1994; 118: 445-50.
    • (1994) Am J Ophthalmol , vol.118 , pp. 445-450
    • Adamis, A.P.1    Miller, J.W.2    Bernal, M.T.3
  • 7
    • 0030666454 scopus 로고    scopus 로고
    • Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant
    • Hotta N, Nakamura J, Sakakibara F, et al. Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant. Am J Physiol 1997; 273: E965-971.
    • (1997) Am J Physiol , vol.273
    • Hotta, N.1    Nakamura, J.2    Sakakibara, F.3
  • 8
    • 0037375171 scopus 로고    scopus 로고
    • The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes
    • Miwa K, Nakamura J, Hamada Y, et al. The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes. Diabetes Res Clin Pract 2003; 60: 1-9.
    • (2003) Diabetes Res Clin Pract , vol.60 , pp. 1-9
    • Miwa, K.1    Nakamura, J.2    Hamada, Y.3
  • 9
    • 4344658774 scopus 로고    scopus 로고
    • Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy
    • Dagher Z, Park YS, Asnaghi V, Hoehn T, Gerhardinger C, Lorenzi M. Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy. Diabetes 2004; 53: 2404-11.
    • (2004) Diabetes , vol.53 , pp. 2404-2411
    • Dagher, Z.1    Park, Y.S.2    Asnaghi, V.3    Hoehn, T.4    Gerhardinger, C.5    Lorenzi, M.6
  • 10
    • 0024570167 scopus 로고
    • Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells
    • Lee TS, MacGregor LC, Fluharty SJ, King GL. Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells. J Clin Invest 1989; 83: 90-4.
    • (1989) J Clin Invest , vol.83 , pp. 90-94
    • Lee, T.S.1    Macgregor, L.C.2    Fluharty, S.J.3    King, G.L.4
  • 11
    • 15644366961 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor
    • Aiello LP, Bursell SE, Clermont A, et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes 1997; 46: 1473-80.
    • (1997) Diabetes , vol.46 , pp. 1473-1480
    • Aiello, L.P.1    Bursell, S.E.2    Clermont, A.3
  • 12
    • 0032836509 scopus 로고    scopus 로고
    • A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats
    • Nakamura J, Kato K, Hamada Y, et al. A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats. Diabetes 1999; 48: 2090-5.
    • (1999) Diabetes , vol.48 , pp. 2090-2095
    • Nakamura, J.1    Kato, K.2    Hamada, Y.3
  • 13
    • 0032968131 scopus 로고    scopus 로고
    • Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations
    • Hammes HP, Brownlee M, Lin J, Schleicher E, Bretzel RG. Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations. Diabetologia 1999; 42: 603-7.
    • (1999) Diabetologia , vol.42 , pp. 603-607
    • Hammes, H.P.1    Brownlee, M.2    Lin, J.3    Schleicher, E.4    Bretzel, R.G.5
  • 14
    • 0036939182 scopus 로고    scopus 로고
    • The potential role of PKC beta in diabetic retinopathy and macular edema
    • Aiello LP. The potential role of PKC beta in diabetic retinopathy and macular edema. Surv Ophthalmol 2002; 47 (suppl 2): S263-9.
    • (2002) Surv Ophthalmol , vol.47 , Issue.SUPPL. 2
    • Aiello, L.P.1
  • 15
    • 10144222652 scopus 로고    scopus 로고
    • Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo
    • Kuroki M, Voest EE, Amano S, et al. Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. J Clin Invest 1996; 98: 1667-75.
    • (1996) J Clin Invest , vol.98 , pp. 1667-1675
    • Kuroki, M.1    Voest, E.E.2    Amano, S.3
  • 17
    • 0030805762 scopus 로고    scopus 로고
    • The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas
    • Murata T, Nagai R, Ishibashi T, Inomuta H, Ikeda K, Horiuchi S. The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas. Diabetologia 1997; 40: 764-9.
    • (1997) Diabetologia , vol.40 , pp. 764-769
    • Murata, T.1    Nagai, R.2    Ishibashi, T.3    Inomuta, H.4    Ikeda, K.5    Horiuchi, S.6
  • 18
    • 0033028542 scopus 로고    scopus 로고
    • Differential accumulation of advanced glycation end products in the course of diabetic retinopathy
    • Hammes HP, Alt A, Niwa T, et al. Differential accumulation of advanced glycation end products in the course of diabetic retinopathy. Diabetologia 1999; 42: 728-36.
    • (1999) Diabetologia , vol.42 , pp. 728-736
    • Hammes, H.P.1    Alt, A.2    Niwa, T.3
  • 19
    • 0031910005 scopus 로고    scopus 로고
    • The relationship of glycaemic level to advanced glycation end-product (AGE) accumulation and retinal pathology in the spontaneous diabetic hamster
    • Hammes HP, Wellensiek B, Kloting I, Sickel E, Bretzel RG, Brownlee M. The relationship of glycaemic level to advanced glycation end-product (AGE) accumulation and retinal pathology in the spontaneous diabetic hamster. Diabetologia 1998; 41: 165-70.
    • (1998) Diabetologia , vol.41 , pp. 165-170
    • Hammes, H.P.1    Wellensiek, B.2    Kloting, I.3    Sickel, E.4    Bretzel, R.G.5    Brownlee, M.6
  • 21
    • 0033868806 scopus 로고    scopus 로고
    • PKC-beta inhibitor (LY333531) attenuates leukocyte entrapment in retinal microcirculation of diabetic rats
    • Nonaka A, Kiryu J, Tsujikawa A, et al. PKC-beta inhibitor (LY333531) attenuates leukocyte entrapment in retinal microcirculation of diabetic rats. Invest Ophthalmol Vis Sci 2000; 41: 2702-6.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 2702-2706
    • Nonaka, A.1    Kiryu, J.2    Tsujikawa, A.3
  • 22
    • 21344435254 scopus 로고    scopus 로고
    • The effect of ruboxistaurin on visual loss in patients with moderately severe to very severe nonproliferative diabetic retinopathy: Initial results of the Protein Kinase C beta Inhibitor Diabetic Retinopathy Study (PKC-DRS) multicenter randomized clinical trial
    • The effect of ruboxistaurin on visual loss in patients with moderately severe to very severe nonproliferative diabetic retinopathy: initial results of the Protein Kinase C beta Inhibitor Diabetic Retinopathy Study (PKC-DRS) multicenter randomized clinical trial. Diabetes 2005; 54: 2188-97.
    • (2005) Diabetes , vol.54 , pp. 2188-2197
  • 23
    • 33644842187 scopus 로고    scopus 로고
    • Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients
    • Aiello LP, Clermont A, Arora V, Davis MD, Sheetz MJ, Bursell SE. Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients. Invest Ophthalmol Vis Sci 2006; 47: 86-92.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 86-92
    • Aiello, L.P.1    Clermont, A.2    Arora, V.3    Davis, M.D.4    Sheetz, M.J.5    Bursell, S.E.6
  • 24
    • 0026323337 scopus 로고
    • Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy
    • Hammes HP, Martin S, Federlin K, Geisen K, Brownlee M. Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy. Proc Natl Acad Sci U S A 1991; 88: 11555-8.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 11555-11558
    • Hammes, H.P.1    Martin, S.2    Federlin, K.3    Geisen, K.4    Brownlee, M.5
  • 25
    • 0029008829 scopus 로고
    • Secondary intervention with aminoguanidine retards the progression of diabetic retinopathy in the rat model
    • Hammes HP, Strodter D, Weiss A, Bretzel RG, Federlin K, Brownlee M. Secondary intervention with aminoguanidine retards the progression of diabetic retinopathy in the rat model. Diabetologia 1995; 38: 656-60.
    • (1995) Diabetologia , vol.38 , pp. 656-660
    • Hammes, H.P.1    Strodter, D.2    Weiss, A.3    Bretzel, R.G.4    Federlin, K.5    Brownlee, M.6
  • 26
    • 0034570430 scopus 로고    scopus 로고
    • A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications
    • Shinohara M, Masuyama T, Shoda T, et al. A new spontaneously diabetic non-obese Torii rat strain with severe ocular complications. Int J Exp Diabetes Res 2000; 1: 89-100.
    • (2000) Int J Exp Diabetes Res , vol.1 , pp. 89-100
    • Shinohara, M.1    Masuyama, T.2    Shoda, T.3
  • 27
    • 33751183719 scopus 로고    scopus 로고
    • Characteristics of diabetic retinopathy in SDT Rats
    • Kakehashi A, Saito Y, Mori K, et al. Characteristics of diabetic retinopathy in SDT Rats. Diabetes Metab Res Rev 2006; 22: 455-61.
    • (2006) Diabetes Metab Res Rev , vol.22 , pp. 455-461
    • Kakehashi, A.1    Saito, Y.2    Mori, K.3
  • 28
    • 4544341580 scopus 로고    scopus 로고
    • Elevated serum levels of N(epsilon)-carboxymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema
    • Boehm BO, Schilling S, Rosinger S, et al. Elevated serum levels of N(epsilon)-carboxymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema. Diabetologia 2004; 47: 1376-79.
    • (2004) Diabetologia , vol.47 , pp. 1376-1379
    • Boehm, B.O.1    Schilling, S.2    Rosinger, S.3
  • 29
    • 13444281983 scopus 로고    scopus 로고
    • Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes
    • Hirata K, Kubo K. Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes. Endocr J 2004; 51: 537-44.
    • (2004) Endocr J , vol.51 , pp. 537-544
    • Hirata, K.1    Kubo, K.2
  • 30
    • 0030512148 scopus 로고    scopus 로고
    • Advanced glycation end-products in diabetic nephropathy
    • Sugiyama S, Miyata T, Horie K, et al. Advanced glycation end-products in diabetic nephropathy. Nephrol Dial Transplant 1996; 11 (suppl 5): 91-4.
    • (1996) Nephrol Dial Transplant , vol.11 , Issue.SUPPL. 5 , pp. 91-94
    • Sugiyama, S.1    Miyata, T.2    Horie, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.