Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 1, 1997, Pages 275-280

  Iervasi, Giorgio ^a   Clerico, Aldo ^a   Bonini, Rita ^a   Manfredi, Cristina ^a   Berti, Sergio ^a   Ravani, Marcello ^a   Palmieri, Cataldo ^a   Carpi, Angelo ^a   Biagini, Andrea ^a   Chopra, Inder J ^b  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; LIOTHYRONINE; THYROXINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DOSE RESPONSE; FEMALE; HEART ARREST; HORMONE RESPONSE; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; INTRAVENOUS DRUG ADMINISTRATION; LIOTHYRONINE BLOOD LEVEL; MALE; PRIORITY JOURNAL; THYROID FUNCTION; THYROXINE BLOOD LEVEL;

EID: 8044257702     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.82.1.3675     Document Type: Article

References (21)

1. Figge HL, Figge J. 1990 The effects of amiodarone on thyroid hormone function: a review of the physiology and clinical manifestations. J Clin Pharmacol. 30:588-595.
2. Gill J, Heel RC, Fitton A. 1992 Amiodarone. An overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias. Drugs. 43:69-110.
3. Unger J, Lambert M, Jonckheer MH, Denayer Ph. 1993 Amiodarone and the thyroid: pharmacological, toxic and therapeutic effects. J Intern Med. 233:435-43.
4. Polikar R, Burger AG, Scherrer U, Nicod P. 1993 The thyroid and the heart. Circulation. 87:1435-1441.
5. Kannan R, Chopra IJ, Ookhtens M, Singh BN. 1990 Effect of amiodarone on non-deiodinative pathway of thyroid hormone metabolism. Acta Endocrinol. 122:249-254.
6. 4 monodeiodination indicative of hyperthyroidism? J Clin Endocrinol Metab. 55:1058-1065.
7. Hershman JM, Nademanee K, Sugawara M, et al. 1986 Thyroxine and triiodothyronine kinetics in cardiac patients taking amiodarone. Acta Endocrinol. 111:193-199.
8. Biagini A, Iervasi G, Clerico A, et al. 1995 Peripheral thyroid hormone metabolism in patients with complex ventricular arrhythmias. Am J Cardiol. 75:630-633.
9. Iervasi G, Clerico A, Berti S, et al. 1996 Normalization of peripheral thyroid hormone metabolism induced by successful chronic amiodarone treatment in patients with ventricular arrhythmias. Eur J Clin Invest. 26:382-390.
10. Burger A, Dinichert D, Nicod P, Jenny M, Lemarchand-Béraud T, Vallotton MB. 1976 Effect of amiodarone on serum triiodothyronine, reverse triiodothyronine, thyroxine, and thyrotropin. J Clin Invest. 58:255-259.
11. Rao HR, Buckell HM, Rege VP, Spathis GS. 1987 Thyrotropin hyperresponsiveness to TRH despite hyperthyroxinemia in amiodarone-treated subjects. Metabolism. 36:1086-1090.
12. Melmed S, Nademanee K, Reed AW, Hendrickson JA, Singh BN, Hersham JM. 1981 Hyperthyroxinemia with bradycardia and normal thyrotropin secretion after amiodarone administration. J Clin Endocrinol Metab. 53:997-1001.
13. Amico JA, Richardson V, Alpert B, Klein I. 1984 Clinical and chemical assessment of thyroid function during therapy with amiodarone. Arch Intern Med. 144:487-490.
14. Zipes DP. 1992 Management of cardiac arrhythmias: pharmacological, electrical, and surgical techniques. In: Braunwaild E (ed) Heart Disease: a Textbook of Cardiovascular Medicine, ed 4. Philadelphia: W.B. Saunders; 628-666.
15. Singh BN, Sarma JSM. 1994 Amiodarone and amiodarone derivatives. In: Singh BN, Dzau VJ, Vanhoutte PM, and Woosley RL (eds) Cardiovascular Pharmacology and Therapeutics. New York: Churchill Livingstone; 689-709.
16. Woosley RL. 1994 Anriarrhythmic drugs. In: Sclant RC, Alexander RW (eds) The Heart, Arteries and Veins, ed 8. New York: McGraw-Hill; 775-805.
17. Manfredi C, Clerico A, Iervasi G, et al. 1995 Measurement of serum amiodarone and desethylamiodarone by HPLC: its usefulness in the follow-up of arrhythmic patients treated with amiodarone. Int J Clin Pharmacol. 15:87-93.
18. Nicoloff JT, LoPresti JS. 1991 Nonthyroidal illness. In: Braverman LE, Utiger RD (eds) The Thyroid. A Fundamental and Clinical Text, ed 6. Philadelphia: J.B. Lippincott; 357-368.
19. Burch HB. 1995 Abnormal thyroid function test results in euthyroid persons. In: Becker KL (ed) Principles and Practice of Endocrinology and Metabolism, ed 2. Philadelphia: J.B. Lippincott; 323-332.
20. Kennedy RL, Griffiths H, Gray TA. 1989 Amiodarone and the thyroid. Clin Chem. 35:1882-1887.
21. Latham KR, Sellitti DF, Goldstein RE. 1987 Interaction of amiodarone and desethylamiodarone with solubized nuclear thyroid hormone receptor. J Am Coll Cardiol. 9:872-877.