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Volumn 138, Issue 3, 1997, Pages 947-954

Pathophysiological significance of the obese gene product, leptin, in ventromedial hypothalamus (VMH)lesioned rats: Evidence for loss of its satiety effect in VMH-lesioned rats

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

EID: 8044227781     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.3.4989     Document Type: Article
Times cited : (130)

References (45)
  • 1
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman DL 1978 Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14:141-148
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 11
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS 1995 Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med 1:1311-1314
    • (1995) Nat Med , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Lollmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 16
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P 1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 19
    • 0019497652 scopus 로고
    • Hypothalamic obesity: The autonomic hypothesis and the lateral hypothalamus
    • Bray GA, Inoue S, Nishizawa Y 1981 Hypothalamic obesity: the autonomic hypothesis and the lateral hypothalamus. Diabetologia 20:366-377
    • (1981) Diabetologia , vol.20 , pp. 366-377
    • Bray, G.A.1    Inoue, S.2    Nishizawa, Y.3
  • 21
    • 0029949063 scopus 로고    scopus 로고
    • Leptin activation in hypothalamus
    • Woods AJ, Stock MJ 1996 Leptin activation in hypothalamus. Nature 381:745
    • (1996) Nature , vol.381 , pp. 745
    • Woods, A.J.1    Stock, M.J.2
  • 23
    • 0029895233 scopus 로고    scopus 로고
    • Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
    • Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P 1996 Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett 387:113-116
    • (1996) FEBS Lett , vol.387 , pp. 113-116
    • Mercer, J.G.1    Hoggard, N.2    Williams, L.M.3    Lawrence, C.B.4    Hannah, L.T.5    Trayhurn, P.6
  • 26
    • 70449255388 scopus 로고
    • The effects of lesions in the hypothalamus in parabiotic rats
    • Hervey GR 1959 The effects of lesions in the hypothalamus in parabiotic rats. J Physiol 145:336-352
    • (1959) J Physiol , vol.145 , pp. 336-352
    • Hervey, G.R.1
  • 27
    • 0019061916 scopus 로고
    • Evidence for a circulating ergostatic factor: Studies on parabiotic rats
    • Nishizawa Y, Bray GA 1980 Evidence for a circulating ergostatic factor: studies on parabiotic rats. Am J Physiol 239:R344-R351
    • (1980) Am J Physiol , vol.239
    • Nishizawa, Y.1    Bray, G.A.2
  • 30
    • 14744276967 scopus 로고
    • High-level direct expression of semi-synthetic human interleukin-6 in Escherichia coli and production of N-terminus Met-free product
    • Yasueda H, Nagase K, Hosoda A, Akiyama Y, Yamada K 1990 High-level direct expression of semi-synthetic human interleukin-6 in Escherichia coli and production of N-terminus Met-free product. BioTechnology 8:1036-1040
    • (1990) BioTechnology , vol.8 , pp. 1036-1040
    • Yasueda, H.1    Nagase, K.2    Hosoda, A.3    Akiyama, Y.4    Yamada, K.5
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities utilizing the principle of protein-dye binding
    • Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 32
    • 0022476780 scopus 로고
    • Preventive effect of cholecystokinin octapeptide on experimental amnesia in rats
    • Katsuura G, Itoh S 1986 Preventive effect of cholecystokinin octapeptide on experimental amnesia in rats. Peptides 7:105-110
    • (1986) Peptides , vol.7 , pp. 105-110
    • Katsuura, G.1    Itoh, S.2
  • 33
    • 0014608866 scopus 로고
    • Effects of parabiosis of normal with genetically diabetic mice
    • Coleman DL, Hummel KP 1969 Effects of parabiosis of normal with genetically diabetic mice. Am J Physiol 217:1298-1304
    • (1969) Am J Physiol , vol.217 , pp. 1298-1304
    • Coleman, D.L.1    Hummel, K.P.2
  • 34
    • 0023187117 scopus 로고
    • Body composition of lean and obese Zucker rats in parabiosis
    • Harris RBS, Hervey E, Hervey GR, Tobin G 1987 Body composition of lean and obese Zucker rats in parabiosis. Int J Obes 11:275-283
    • (1987) Int J Obes , vol.11 , pp. 275-283
    • Harris, R.B.S.1    Hervey, E.2    Hervey, G.R.3    Tobin, G.4
  • 38
    • 0018770622 scopus 로고
    • Acute hyperinsulinemia and its reversal by vagotomy after lesions of the ventromedial hypothalamus in anesthetized rats
    • Berthoud HR, Jeanrenaud B 1979 Acute hyperinsulinemia and its reversal by vagotomy after lesions of the ventromedial hypothalamus in anesthetized rats. Endocrinology 105:146-151
    • (1979) Endocrinology , vol.105 , pp. 146-151
    • Berthoud, H.R.1    Jeanrenaud, B.2
  • 40
    • 0028826355 scopus 로고
    • Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system
    • Trayhurn P, Duncan JS, Rayner V 1995 Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system. Biochem J 311:729-733
    • (1995) Biochem J , vol.311 , pp. 729-733
    • Trayhurn, P.1    Duncan, J.S.2    Rayner, V.3
  • 42
    • 0029166158 scopus 로고
    • Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice
    • Trayhurn P, Thomas MEA, Duncan JS, Rayner DV 1995 Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice. FEBS Lett 368:488-490
    • (1995) FEBS Lett , vol.368 , pp. 488-490
    • Trayhurn, P.1    Thomas, M.E.A.2    Duncan, J.S.3    Rayner, D.V.4
  • 43
    • 0028821861 scopus 로고
    • The ob gene and insulin: A relationship leading to clues to the understanding of obesity
    • Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B 1995 The ob gene and insulin: a relationship leading to clues to the understanding of obesity. Diabetes 44:1467-1470
    • (1995) Diabetes , vol.44 , pp. 1467-1470
    • Cusin, I.1    Sainsbury, A.2    Doyle, P.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 45
    • 0022392689 scopus 로고
    • Effect of gold thioglucose-induced obesity on adipose tissue weight and cellularity in male and female mice suckled in large and small litters: Investigations into sex differences and site differences
    • Enser M, Roberts J, Whittington F 1985 Effect of gold thioglucose-induced obesity on adipose tissue weight and cellularity in male and female mice suckled in large and small litters: investigations into sex differences and site differences. Br J Nutr 54:645-654
    • (1985) Br J Nutr , vol.54 , pp. 645-654
    • Enser, M.1    Roberts, J.2    Whittington, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.