Effect of maternal tobacco smoking or exposure to second-hand smoke on the levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine of mother and the first urine of newborn

Journal of Physiology and Pharmacology

Volumn 62, Issue 3, 2011, Pages 377-383

  Florek, E ^a   Piekoszewski, W ^b   Basior, A ^a   Merritt, A T ^c   Mazela, J ^a   Lechowicz, W ^d   Kornacka, M K ^e   Kramer, L ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

^c LOMA LINDA UNIVERSITY   (United States)

^d INSTITUTE OF FORENSIC RESEARCH   (Poland)

^e MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

4 (methylnitrosamino) 1 (3 pyridyl) 1 butanol (NNAL); Biomarkers; Cotinine; Newborn; Pregnancy; Secondhand smoke

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; COTININE; CREATININE; NITROSAMINE;

ADULT; ARTICLE; CHEMICAL CARCINOGENESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREATININE URINE LEVEL; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MATERNAL SMOKING; NEWBORN; PASSIVE SMOKING; PRENATAL EXPOSURE; SMOKING HABIT; TANDEM MASS SPECTROMETRY; URINALYSIS;

ADULT; BIOLOGICAL MARKERS; BIRTH WEIGHT; CARCINOGENS; COTININE; CREATININE; FEMALE; HUMANS; INFANT, NEWBORN; MOTHERS; NICOTINE; NITROSAMINES; PREGNANCY; PYRIDINES; SMOKING; TOBACCO; TOBACCO SMOKE POLLUTION;

EID: 80355143505     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Hecht SS. DNA adduct formation from tobacco-specific Nnitrosamines. Mut Res 1999; 424: 127-142.
2. Mucha L, Stephenson J, Morandi N, Dirani R. Meta-analysis of disease risk associated with smoking, by gender and intensity of smoking. Gend Med 2006; 3: 279-291.
3. Vena JE. Lung, breast, bladder and rectal cancer. Rev Environ Health 2010; 25: 39-45.
4. Benowitz NL. Biomarkers of environmental tobacco smoke exposure. Environ Health Perspect 1999; 107(Suppl 2): 349-355.
5. Florek E, Piekoszewski W, Rybakowski L, Moczko J. Using the questionnaire and cotinine concentration in urine for study smoking habit and exposure to ETS of pregnant women. Przegl Lek 2004; 61: 993-996.
6. Gorber SC, Schofield-Hurwitz S, Hardt J, Levasseur G, Tremblay M. The accuracy of self-reported smoking: a systematic review of the relationship between self-reported and cotinine-assessed smoking status. Nicotine Tob Res 2009; 11: 12-24.
7. Lin RK, Hsieh YS, Lin P, et al. Tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients. J Clin Invest 2010; 120: 21-32.
8. Zhou H, Calaf GM, Hei TK. Malignant transformation of human bronchial epithelial cells with the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Int J Cancer 2003; 106: 821-826.
9. Joseph AM, Hecht SS, Murphy SE, et al. Relationships between cigarette consumption and biomarkers of tobacco toxin exposure. Cancer Epidemiol Biomarkers Prev 2005; 14: 2963-2968.
10. Murphy SE, Link CA, Jensen J, et al. A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers. Cancer Epidemiol Biomarkers Prev 2004; 13: 1617-1623.
11. Florek E, Breborowicz GH, Lechowicz W, et al. Cotinine in urine of mother and their newborn and in cord serum and placenta as a biomarker of foetal exposure to tobacco smoke. (in Polish). Przegl Lek 2006; 63: 900-906.
12. Rogers JM. Tobacco and pregnancy. Reprod Toxicol 2009; 28: 152-160.
13. Shaw JL, Dey SK, Critchley HO, Horne AW. Current knowledge of the aetiology of human tubal ectopic pregnancy. Hum Reprod Update 2010; 16: 432-444.
14. The European Tobacco Control Report. World Health Organization, Regional Office for Europe, Copenhagen, Denmark, 2007.
15. The Tobacco Atlas. American Cancer Society, Atlanta, USA, 2006.
16. Arnould JP, Verhoest P, Bach V, Libert JP, Belegaud J. Detection of benzo[a]pyrene-DNA adducts in human placenta and umbilical cord blood. Hum Exp Toxicol 1997; 16: 716-721.
17. Milunsky A, Carmella SG, Ye M, Hecht SS. A tobaccospecific carcinogen in the fetus. Prenat Diagn 2000; 20: 307-310.
18. Florek E, Piekoszewski W, Wrzosek J. Relationship between the level and time of exposure to tobacco smoke and urine nicotine and cotinine concentration. Pol J Pharmacol 2003; 55: 97-102.
19. Florek E, Piekoszewski W, Lechowicz W, Szymanska A, Kornacka MK. Determination of 4-(methylnirosamino)-4-(3-pyridyl)-1-butanol (NNAL) in urine of pregnant women by means of LC/MS/MS. (in Polish). Przegl Lek 2006; 63: 926-931.
20. Bramer SL, Kallungal BA. Clinical considerations in study design that use cotinine as biomarker. Biomarkers 2003; 8: 187-203.
21. Florek E, Piekoszewski W, Kornacka MK, Koroniak H, Wolna M, Krol A. Determination of cadmium in urine of tobacco smoking pregnant women. (in Polish). Przegl Lek 2004; 61: 1109-1112.
22. Byrd GD, Ogden MW. Liquid chromatographic/tandem mass spectrometry method for the determination of the tobacco-specific nitrosamines metabolite NNAL in smokers' urine. J Mass Spectrom 2003; 38: 98-107.
23. Anderson KE, Hammons GJ, Kadlubar FF, et al. Metabolic activation of aromatic amines by human pancreas. Carcinogenesis 1997; 18: 1085-1092.
24. Lackmann GM, Salzberger U, Tollner U, Chen M, Carmella SG, Hecht SS. Metabolites of a tobacco-specific carcinogen in urine from newborns. J Natl Cancer Inst 1999; 91: 459-465.
25. Jorquera R, Castonguay A, Schuller HM. Placental transfer of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone instilled intratracheally in Syrian golden hamsters. Cancer Res 1992; 52: 3273-3280.
26. Wong HL, Zhang X, Zhang QY, et al. Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes. Chem Res Toxicol 2005; 18: 913-918.
27. Collazo NR, Sultatos LG. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes. Biochem Pharmacol 1995; 50: 1933-1941.
28. Koppang N, Rivenson A, Reith A, Dahle HK, Evensen O, Hoffmann D. A study of tobacco carcinogenesis. XLVIII. Carcinogenicity of N'-nitrosonornicotine in mink (Mustela vision). Carcinogenesis 1992; 13: 1957-1960.
29. Hecht SS, Murphy SE, Carmella SG. Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes. Cancer Epidemiol Biomarkers Prev 2005; 14: 693-698.
30. Hecht SS, Carmella SG, Folies PG, Murphy SE. Biomarkers for human uptake and metabolic activation of tobaccospecific nitrosamines. Cancer Res 1994; 54: 1912-1917.
31. Carmella SG, Akerkar S, Hecht SS. Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers urine. Cancer Res 1993; 53: 721-724.
32. Carmella SG, Akerkar S, Richie JP Jr, Hecht SS. Intraindividual and interindividual differences in metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers' urine. Cancer Epidemiol Biomarkers Prev 1995; 4: 635-642.
33. Carmella SG, Han S, Villalta PW, Hecht SS. Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in smokers' blood. Cancer Epidemiol Biomarkers Prev 2005; 14: 2669-2672.
34. Lerner L, Weiner D, Katz R, Reznick AZ, Pollack S. Increased pro-inflammatory activity and impairment of human monocyte differentiation induced by in vitro exposure to cigarette smoke. J Physiol Pharmacol 2009, 60(Suppl 5); 81-86.
35. Weiner D, Khankin EV, Levy Y, Reznick AZ. Effects of cigarette smoke borne reactive nitrogen species on salivary a-amylase activity and protein modifications. J Physiol Pharmacol 2009, 60(Suppl 5); 127-132.
36. Oberg M, Jaakkota MS, Woodward A, Peruga A, Ustun A. Worldwide burden of disease from exposure to second-hand smoke a retrospective analysis of data from 192 countries. Lancet 2010; 377: 61922-61928.