Quantification of total and free concentrations of R- and S-warfarin in human plasma by ultrafiltration and LC-MS/MS

Analytical and Bioanalytical Chemistry

Volumn 401, Issue 7, 2011, Pages 2187-2193

  Jensen, Berit Packert ^a   Chin, Paul Ken Leong ^a   Begg, Evan James ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Enantiomer; Free; Plasma; Ultrafiltration; Unbound; Warfarin

Indexed keywords

CALIBRATION CURVES; CLINICAL STUDY; EXTRACTION RECOVERY; FREE; FREE CONCENTRATION; HUMAN PLASMAS; INTERNAL STANDARDS; ION TRANSITION; ISOCRATIC ELUTION; LC-MS/MS; LIQUID-LIQUID EXTRACTION; LOWER LIMIT OF QUANTIFICATIONS; MATRIX EFFECTS; METHYL TERT BUTYL ETHER; NON-SPECIFIC BINDING; PLASMA PROTEIN; ULTRAFILTRATION DEVICES; UNBOUND; WARFARIN; WARFARIN ENANTIOMERS;

ACETIC ACID; CHIRALITY; ELECTROSPRAY IONIZATION; ENANTIOMERS; ETHERS; LIQUIDS; METHANOL; SOLVENT EXTRACTION; ULTRAFILTRATION;

PLASMAS;

WARFARIN;

ARTICLE; BLOOD; CALIBRATION; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; STANDARD; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; LIQUID-LIQUID EXTRACTION; REFERENCE STANDARDS; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION; WARFARIN;

EID: 80255134496     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5303-x     Document Type: Article

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