Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins

Biochemistry

Volumn 50, Issue 44, 2011, Pages 9511-9519

  Peshenko, Igor V ^a   Olshevskaya, Elena V ^a   Azadi, Seifollah ^b   Molday, Laurie L ^b   Molday, Robert S ^b   Dizhoor, Alexander M ^a  

^a SALUS UNIVERSITY   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC ACTIVATION; ALLOSTERIC MODULATORS; BASAL ACTIVITIES; BINDING PROTEINS; CYCLASES; DYNAMIC REGULATION; GUANYLYL CYCLASE; HEK293 CELLS; INHIBITORY ACTIVITY; INTRACELLULAR CA; OUTER SEGMENTS; RETINAL DEGENERATIONS; STABLE EXPRESSION; SUBMICROMOLAR CONCENTRATIONS;

CALCIUM; CHEMICAL ACTIVATION; OPHTHALMOLOGY; PROTEINS; VISION;

CATALYST ACTIVITY;

GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; RECOMBINANT PROTEIN; RETINA DEGENERATION 3 PROTEIN; RETINA MEMBRANE GUANYLYL CYCLASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CATALYSIS; HUMAN; HUMAN CELL; LEBER CONGENITAL AMAUROSIS; MOUSE; NONHUMAN; PHOTORECEPTOR OUTER SEGMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEGENERATION;

ANIMALS; BINDING, COMPETITIVE; CATALYSIS; CODON, NONSENSE; EYE PROTEINS; GUANYLATE CYCLASE; GUANYLATE CYCLASE-ACTIVATING PROTEINS; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MUTATION, MISSENSE; NUCLEAR PROTEINS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; RETINA; ROD CELL OUTER SEGMENT;

VERTEBRATA;

EID: 80155203814     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201342b     Document Type: Article

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