Responsiveness of the major birch allergen Bet v 1 scaffold to the gastric environment: Impact on structure and allergenic activity

Molecular Nutrition and Food Research

Volumn 55, Issue 11, 2011, Pages 1690-1699

  Sancho, Ana I ^a   Wangorsch, Andrea ^b   Jensen, Bettina M ^c,d   Watson, Andrew ^a   Alexeev, Yuri ^a   Johnson, Phil E ^a   Mackie, Alan R ^a   Neubauer, Angela ^e   Reese, Gerald ^b   Ballmer Weber, Barbara ^f   Hoffmann Sommergruber, Karin ^g   Skov, Per S ^c   Vieths, Stefan ^b   Mills, Elisabeth N Clare ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b PAUL EHRLICH INSTITUT   (Germany)

^c RefLab   (Denmark)

^d Dermato Allergological Dept K CUH Gentofte   (Denmark)

^e BIOMAY AG   (Austria)

^f UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^g MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bet v 1 homologues; Food allergy; Lipid protein interaction; Pepsinolysis; Phosphatidylcholine

Indexed keywords

ALLERGEN; DIMYRISTOYLPHOSPHATIDYLCHOLINE; IMMUNOGLOBULIN E; LIPOSOME; PEPSIN A; PHOSPHATIDYLCHOLINE; PLANT ANTIGEN; RBET V 1A MUT1 6 ALLERGEN, BIRCH; RBET V 1A MUT1-6 ALLERGEN, BIRCH; RECOMBINANT PROTEIN; SURFACTANT; VEGETABLE PROTEIN;

ANTIGEN ANTIBODY REACTION; ARTICLE; BASOPHIL DEGRANULATION TEST; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; FOOD ALLERGY; GENETICS; HUMAN; IMMUNOLOGY; KINETICS; METABOLISM; PH; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; STOMACH JUICE;

ALLERGENS; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, PLANT; BASOPHIL DEGRANULATION TEST; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FOOD HYPERSENSITIVITY; GASTRIC JUICE; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN E; KINETICS; MODELS, MOLECULAR; PEPSIN A; PHOSPHATIDYLCHOLINES; PLANT PROTEINS; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEOLYSIS; RECOMBINANT PROTEINS; SURFACE-ACTIVE AGENTS; UNILAMELLAR LIPOSOMES;

APIUM GRAVEOLENS RAPACEUM; CORYLUS; MALUS X DOMESTICA; PRUNUS PERSICA;

EID: 80155194971     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100025     Document Type: Article

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