Pathophysiological modeling of obsessive-compulsive disorder: Challenges, and progress

Biological Psychiatry

Volumn 70, Issue 11, 2011, Pages 1002-1003

  Pittenger, Christopher ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOMIPRAMINE; DESIPRAMINE; FLUOXETINE; SEROTONIN 1 RECEPTOR; SEROTONIN 1B AGONIST;

CONSTRUCT VALIDITY; GILLES DE LA TOURETTE SYNDROME; HUMAN; NONHUMAN; NOTE; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PHENOTYPE; PREDICTIVE VALIDITY; PRIORITY JOURNAL; SCHIZOPHRENIA;

ANIMALS; FEMALE; OBSESSIVE-COMPULSIVE DISORDER; PREFRONTAL CORTEX; RECEPTOR, SEROTONIN, 5-HT1B;

EID: 80155191246     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.10.005     Document Type: Note

References (13)

1. B.K. Harvey, C.T. Richie, B.J. Hoffer, and M. Airavaara Transgenic animal models of neurodegeneration based on human genetic studies J Neural Transm 118 2011 27 45
2. E.J. Nestler, and S.E. Hyman Animal models of neuropsychiatric disorders Nat Neurosci 13 2010 1161 1169
3. L.M. Koran, G.L. Hanna, E. Hollander, G. Nestadt, and H.B. Simpson Practice guideline for the treatment of patients with obsessive-compulsive disorder Am J Psychiatry 164 7 Suppl 2007 5 53
4. T.V. Maia, R.E. Cooney, and B.S. Peterson The neural bases of obsessive-compulsive disorder in children and adults Dev Psychopathol 20 2008 1251 1283
5. M.H. Bloch, and C. Pittenger The genetics of obsessive-compulsive disorder Curr Psychiatry Rev 6 2010 91 103
6. J.M. Welch, J. Lu, R.M. Rodriguiz, N.C. Trotta, J. Peca, and J.D. Ding Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice Nature 448 2007 894 900 (Pubitemid 47312780)
7. S.V. Shmelkov, A. Hormigo, D. Jing, C.C. Proenca, K.G. Bath, and T. Milde Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice Nat Med 16 2010 598 602 1 p following 602
8. S.L. Andersen, E.A. Greene-Colozzi, and K.C. Sonntag A novel, multiple symptom model of obsessive-compulsive-like behaviors in animals Biol Psychiatry 68 2010 741 747
9. D. Joel The signal attenuation rat model of obsessive-compulsive disorder: a review Psychopharmacology (Berl) 186 2006 487 503 (Pubitemid 43855836)
10. N.A. Shanahan, L.P. Velez, V.L. Masten, and S.C. Dulawa Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice Biol Psychiatry 70 2011 1039 1048
11. R. Gross-Isseroff, R. Cohen, Y. Sasson, H. Voet, and J. Zohar Serotonergic dissection of obsessive compulsive symptoms: a challenge study with m-chlorophenylpiperazine and sumatriptan Neuropsychobiology 50 2004 200 205 (Pubitemid 39279410)
12. N.A. Shanahan, K.A. Holick Pierz, V.L. Masten, C. Waeber, M. Ansorge, and J.A. Gingrich Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice Biol Psychiatry 65 2009 401 408
13. D.L. Braff, M.A. Geyer, and N.R. Swerdlow Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies Psychopharmacology (Berl) 156 2001 234 258 (Pubitemid 32705488)