Effects of 28 days of resistance exercise while consuming commercially available pre- and post-workout supplements, NO-Shotgun and NO-Synthesize on body composition, muscle strength and mass, markers of protein synthesis, and clinical safety markers in males

Nutrition and Metabolism

Volumn 8, Issue , 2011, Pages

  Spillane, Mike ^a   Schwarz, Neil ^a   Leddy, Sarah ^a   Correa, Tracie ^a   Minter, Melodie ^a   Longoria, Victoria ^a   Willoughby, Darryn S ^a  

^a BAYLOR UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; MUSCLE PROTEIN; MYOGENIC FACTOR; NITRIC OXIDE; NITRIC OXIDE SHOTGUN; NITRIC OXIDE SYNTHESIZE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD ANALYSIS; BODY COMPOSITION; BODY MASS; CALORIC INTAKE; CLINICAL CHEMISTRY; DIET SUPPLEMENTATION; HUMAN; HUMAN EXPERIMENT; MACRONUTRIENT; MALE; MUSCLE MASS; MUSCLE STRENGTH; PROTEIN SYNTHESIS; RESISTANCE TRAINING;

EID: 80155165160     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-8-78     Document Type: Article

References (30)

1. Control of the size of the human muscle mass. Rennie M, Wackerhage H, Spangenburg E, Booth F, Annu Rev Physiol 2004 66 799 828 10.1146/annurev. physiol.66.052102.134444 14977422 (Pubitemid 40614463)
2. Influence of mechanical loading on myosin heavy-chain protein and mRNA isoform expression. Caiozzo V, Haddad F, Baker M, Baldwin K, J Appl Physiol 1996 80 1503 1512 8727533 (Pubitemid 26143897)
3. Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Campos G, Luecke T, Wendeln H, Toma K, Hagerman F, Murray T, Ragg K, Ratamess N, Kraemer W, Staron R, Eur J Appl Physiol 2002 88 50 60 10.1007/s00421-002-0681-6 12436270 (Pubitemid 40826308)
4. Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression. Bergstrom D, Penn B, Strand A, Perry R, Rudnicki M, Tapscott S, Mol Cell 2002 9 587 600 10.1016/S1097-2765(02)00481-1 11931766 (Pubitemid 34273789)
5. Time course of molecular responses of human skeletal muscle to acute bouts of resistance exercise. Bickel S, Slade J, Mahoney E, Haddad F, Dudley G, Adams G, J Appl Physiol 2005 98 482 88 15465884 (Pubitemid 40129955)
6. Expression of muscle genes in the mouse embryo. Buckingham M, Houzelstein D, Lyons G, Ontell M, Ott M, Sassoon D, Symp Soc Exp Biol 1992 46 203 17 1341037
7. Effect of protein-supplement timing on strength, power, and body-composition changes in resistance-trained men. Hoffman J, Ratamess N, Tranchina P, Rashti L, Kang J, Faigenbaum A, Int J Sport Nutr Exerc Metab 2009 19 172 85 19478342
8. The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength. Burke D, Chilibeck P, Davidson K, Candow D, Farthing J, Smith-Palmer T, Int J Sport Nutr Exerc Metab 2001 11 349 64 11591884
9. Creatine supplementatin augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training. Olsen S, Aagard P, Kadi F, Tufekovic G, Verney J, Olesen J, Suetta C, Kjaer M, J Physiol 2006 573 525 34 10.1113/jphysiol.2006.107359 16581862 (Pubitemid 43871064)
10. Effect of post-exercise supplement consumption on adaptations to resistance training. Rankin J, Goldman L, Puglisi M, Nickols-Richardson S, Earthman C, Gwazdauskas F, J Am Coll Nutr 2004 23 322 30 15310736 (Pubitemid 39096392)
11. A creatine-protein-carbohydrate supplement enhances responses to resistance training. Cribb P, Williams A, Hayes A, Med Sci Sports Exerc 2007 39 1960 68 10.1249/mss.0b013e31814fb52a 17986903 (Pubitemid 350073359)
12. Effects of a drink containing creatine, amino acids, and protein combined with ten weeks of resistance training on body composition, strength, and anaerobic performance. Beck T, Housh T, Johnson G, Coburn J, Malek M, Cramer J, J Strength Cond Res 2007 21 100 04 17313263
13. Effects of resistance training and protein plus amino acid supplementation on muscle anabolism, mass, and strength. Willoughby D, Stout J, Wilborn C, Amino Acids 2007 32 467 77 10.1007/s00726-006-0398-7 16988909 (Pubitemid 46790929)
14. Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Cribb P, Hayes A, Med Sci Sports Exerc 2006 38 1918 25 10.1249/01.mss.0000233790.08788.3e 17095924 (Pubitemid 44707795)
15. Effects of 28 days of resistance exercise and consuming a commercially available pre-workout supplement, NO-Shotgun, on body composition, muscle strength and mass, markers of satellite cell activation, and clinical safety markers in males. Shelmadine B, Cooke M, Buford T, Hudson G, Redd L, Leutholtz B, Willoughby D, J Int Soc Sports Nutr 2009 5 6 16
16. Carbohydrate supplementation and resistance training. Haff G, Lehmkuhl J, McCoy B, Stone H, J Strength Cond Res 2003 17 187 96 12580676 (Pubitemid 36313332)
17. Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. Beelen M, Tieland M, Gijsen A, Vandereyt H, Kies A, Kuipers H, Saris W, Koopman R, van Loon L, J Nutr 2008 138 2198 204 10.3945/jn.108.092924 18936219
18. Effects of a combined essential amino acids/carbohydrate supplementation on muscle mass, architecture and maximal strength following heavy-load training. Vieillevoye S, Poortmans J, Duchateau J, Carpentier A, Eur J Appl Physiol 2010 110 479 88 10.1007/s00421-010-1520-9 20521064
19. Effects of oral creatine and resistance training on myosin heavy chain expression. Willoughby D, Rosene J, Med Sci Sports Exerc 2001 33 1674 81 10.1097/00005768-200110000-00010 11581551 (Pubitemid 32963868)
20. Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women. Petrella J, Kim J, Cross J, Kosek D, Bamman M, Am J Physiol Endocrinol Metab 2006 291 937 46 10.1152/ajpendo.00190.2006 16772322
21. Acute and chronic hormonal responses to resistance training designed to promote muscle hypertrophy. McCall G, Byrnes W, Fleck S, Dickinson A, Kraemer W, Can J Appl Physiol 1999 24 96 107 10.1139/h99-009 9916184
22. Serum IGF-I-deficiency does not prevent compensatory skeletal muscle hypertrophy in resistance exercise. Matheny R, Merritt E, Zannikos S, Farrar R, Adamo M, Exp Biol Med (Maywood) 2009 234 164 70 10.3181/0808-RM-251
23. Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanism in young vs older adults. Kosek D, Kim J, Petrella J, Cross J, Bamman M, J Appl Physiol 2006 101 531 44 10.1152/japplphysiol.01474.2005 16614355 (Pubitemid 44162363)
24. Growth hormone and the insulin-like growth factor system in myogenesis. Florini J, Ewton D, Coolican S, Endocr Rev 1996 17 481 517 8897022 (Pubitemid 26346639)
25. Time course of myogenic and metabolic gene expression in response to acute exercise in human skeletal muscle. Yang Y, Creer A, Jemiolo B, Trappe S, J Appl Physiol 2005 98 1745 1752 10.1152/japplphysiol.01185.2004 15618316 (Pubitemid 40570785)
26. The MRF4 activation domain is required to induce muscle-specific gene expression. Mak K, Kong Y, Konieczny S, Mol Cell Biol 1992 12 4224 46
27. Differential transactivation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4. Yutzey K, Rhodes S, Konieczny S, Mol Cell Biol 1990 10 3934 44 1695319
28. Neural and hormonal control of expression of myogenic regulatory factor genes during regeneration of Xenopus fast muscles: myogenin and MRF4 mRNA accumulation are neurally regulated oppositely. Nicolas N, Mira J, Gallien C, Chanoine C, Dev Dyn 2000 218 112 22 10.1002/(SICI)1097-0177(200005)218:1<112: :AID-DVDY10>3.0.CO;2-D 10822264 (Pubitemid 30249755)
29. Effects of oral creatine and resistance training on myogenic regulatory factor expression. Willoughby D, Rosene J, Med Sci Sports Exerc 2003 35 769 76 10.1249/01.MSS.0000065005.96298.01 12750586 (Pubitemid 36547379)
30. Oral creatine supplementation faciltates the rehabilitation of disuse atrophy and alters the expression of muscle myogenic factors in humans. Hespel P, Op't Eijnde B, Van Leemputte M, Urso B, Greenhaff P, Labarque V, Dymarkowski S, Van Hecke P, Richter E, J Physiol 2001 536 625 35 10.1111/j.1469-7793.2001. 0625c.xd 11600695 (Pubitemid 32976141)