Immunosuppression and the abdominal aortic aneurysm: Doctor jekyll or mister hyde?

Circulation

Volumn 124, Issue 18, 2011, Pages

  Lindeman, Jan H N ^a   Rabelink, Ton J ^a   Van Bockel, J Hajo ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CD20 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN; CYCLOSPORIN; GELATINASE A; GELATINASE B; INTERLEUKIN 6; INTERLEUKIN 8; MYCOPHENOLIC ACID; MYELOPEROXIDASE; PREDNISONE; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL AORTA ANEURYSM; AGED; AORTA WALL; ARTICLE; B LYMPHOCYTE; CASE REPORT; CD3+ T LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; EMERGENCY SURGERY; FEMALE; HELPER CELL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; MACROPHAGE; MAST CELL; NEUTROPHIL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

AGED; AORTIC ANEURYSM, ABDOMINAL; DISEASE PROGRESSION; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS;

EID: 80155151961     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.008573     Document Type: Article

References (5)

1. Baxter BT, Terrin MC, Dalman RL. Medical management of small abdominal aortic aneurysms. Circulation. 2008;117:1883-1889. (Pubitemid 351507477)
2. Lindeman JH, Abdul-Hussien H, Schaapherder AF, Van Bockel JH, Von der Thüsen JH, Roelen DL, Kleemann R. Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6-and IL-8-dominated inflammatory responses prevail in the human aneurysm. Clin Sci (Lond). 2008; 114:687-697. (Pubitemid 351799328)
3. Rizas KD, Ippagunta N, Tilson MD III. Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm. Cardiol Rev. 2009;17:201-210.
4. Englesbe MJ, Wu AH, Clowes AW, Zierler RE. The prevalence and natural history of aortic aneurysms in heart and abdominal organ transplant patients. J Vasc Surg. 2003;37:27-31. (Pubitemid 36236940)
5. Chizzolini C. T cells, B cells, and polarized immune response in the pathogenesis of fibrosis and systemic sclerosis Curr Opin Rheumatol. 2008;20:707-712.