Production of camptothecin by hairy roots and regenerated transformed shoots of Ophiorrhiza rugosa var. decumbens

Natural Product Research

Volumn 25, Issue 18, 2011, Pages 1762-1765

  Kamble, Suchita ^a   Gopalakrishnan, Roja ^a   Eapen, Susan ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Agrobacterium rhizogenes; Camptothecin; Hairy root; Ophiorrhiza rugosa

Indexed keywords

CAMPTOTHECIN;

ARTICLE; CONTROLLED STUDY; HAIRY ROOT CULTURE; IN VITRO STUDY; MEDICINAL PLANT; NONHUMAN; OPHIORRHIZA RUGOSA DECUMBENS; RHIZOBIUM RHIZOGENES; SHOOT GROWTH; SHOOT REGENERATION;

AGROBACTERIUM; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; PLANT EXTRACTS; PLANT ROOTS; PLANT SHOOTS; RUBIACEAE; TISSUE CULTURE TECHNIQUES;

AGROBACTERIUM RHIZOGENES; OPHIORRHIZA;

EID: 80155130604     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2011.559469     Document Type: Article

References (12)

1. Bodley, A.L., Cumming, J.N., & Shapiro, T.A. (1998). Effect of camptothecin, a topoisomerase I inhibitor on Plasmodium falciparum. Biochemical Pharmacology, 55, 709-711. (Pubitemid 28077830)
2. Hamill, J.D., & Lidgett, A.J. (2000). Hairy root cultures - opportunities and key protocols for studies in metabolic engineering. In P.M. Doran (Ed.), Hairy roots: Culture and applications (pp. 1-30). Sydney: Hardwood Academic.
3. Kitajima, M., Yoshida, S., Yamagata, K., Nakamura, M., Takayama, H., Saito, K., . . . , Aimi, N. (2002). Camptothecin-related alkaloids from hairy roots of Ophiorrhiza pumila. Tetrahedron, 58, 9169-9178. (Pubitemid 35284706)
4. Lorence, A., & Nessler, C.L. (2004). Molecules of interest - camptothecin, over four decades of surprising findings. Phytochemistry, 65, 2735-2749. (Pubitemid 39330172)
5. Potemesil, M. (1994). Camptothecins: from bench research to hospital wards. Cancer Research, 15, 1431-1439.
6. Roja, G. (2006). Comparative studies on the camptothecin content from Nothapodytes foetida and Ophiorrhiza species. Natural Product Research, 20, 85-88. (Pubitemid 41823606)
7. Roja, G. (2008). Micropropagation and production of camptothecin from in vitro plants of Ophiorrhiza rugosa var. decumbens. Natural Product Research, 22, 1017-1023.
8. Roja, G., & Heble, M.R. (1994). The quinoline alkaloids, camptothecin and 9-methoxy camptothecin from tissue cultures and mature trees of Nothapodytes foetida. Phytochemistry, 36, 65-66. (Pubitemid 2079066)
9. Saito, K., Sudo, H., Yamazaki, K., Nakamura, M., Kitajima, M., Takayama, H., & Aimi, N. (2001). Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila. Plant Cell Reports, 20, 267-271. (Pubitemid 32328942)
10. Sudo, H., Yamakawa, T., Yamazaki, M., Aimi, N., & Saito, K. (2002). Bioreactor production of camptothecin by hairy root cultures of Ophiorrhiza pumila. Biotechnology Letters, 24, 359-363. (Pubitemid 34260309)
11. Takeuchi, S., Dobashi, K., Fujimoto, S., Tanaka, K., Suzuki, M., Terashima, Y., . . . , Tayama, T. (1991). A late phase II study of CPT-11 on uterine cervical and ovarian cancer. Research groups of CPT-11 in gynecologic cancers. Gan To Kagaku Ryoho, 18, 1681-1689.
12. Watase, I., Sudo, H., Yamazaki, M., & Saito, K. (2004). Regeneration of transformed Ophiorrhiza pumila plants producing camptothecin. Plant Biotechnology, 21, 337-342. (Pubitemid 40263454)