Micropatterned surfaces to study hyaluronic acid interactions with cancer cells

Journal of Visualized Experiments

Volumn , Issue 46, 2010, Pages

  Dickinson, Laura E ^a   Gerecht, Sharon ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Cancer; Carbodiimide chemistry; Cell adhesion; Hyaluronic acid; Microcontact printing

Indexed keywords

EID: 80055118448     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2413     Document Type: Article

References (11)

1. Toole, B. P., Wight, T. N. & Tammi, M. I. Hyaluronan-cell interactions in cancer and vascular disease. Journal of Biological Chemistry 277, 4593-4596 (2002).
2. Hamilton, S. R. et al. The Hyaluronan Receptors CD44 and Rhamm (CD168) Form Complexes with ERK1,2 That Sustain High Basal Motility in Breast Cancer Cells. Journal of Biological Chemistry 282, 16667-16680, doi:10.1074/jbc.M702078200 (2007).
3. Götte, M. & Yip, G. W. Heparanase, Hyaluronan, and CD44 in Cancers: A Breast Carcinoma Perspective. Cancer Research 66, 10233-10237, doi:10.1158/0008-5472.can-06-1464 (2006).
4. Lord, M. S., Pasqui, D., Barbucci, R. & Milthorpe, B. K. Protein adsorption on derivatives of hyaluronic acid and subsequent cellular response. Journal of Biomedical Materials Research-Part A 91, 635-646 (2009).
5. Barbucci, R. et al. Modification of hyaluronic acid by sulphate groups insertion to obtain a heparin-like molecule. Gazz. Chim. Ital. 125, 169-180 (1995).
6. Morra, M. & Cassinelli, C. Non-fouling properties of polysaccharide-coated surfaces. Journal of Biomaterials Science, Polymer Edition 10, 1107-1124 (1999).
7. Khademhosseini, A. et al. Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures. Biomaterials 25, 3583-3592 (2004).
8. Ibrahim, S., Joddar, B., Craps, M. & Ramamurthi, A. A surface-tethered model to assess size-specific effects of hyaluronan (HA) on endothelial cells. Biomaterials 28, 825-835 (2007).
9. Dickinson, L. E., Ho, C. C., Wang, G. M., Stebe, K. J. & Gerecht, S. Functional surfaces for high-resolution analysis of cancer cell interactions on exogenous hyaluronic acid. Biomaterials 31, 5472-5478 (2010).
10. Gao, F. et al. Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis. Matrix Biology 29, 107-116 (2010).
11. Slevin, M. et al. Hyaluronan-mediated angiogenesis in vascular disease: Uncovering RHAMM and CD44 receptor signaling pathways. Matrix Biology 26, 58-68 (2007).