Distal leucines are key functional determinants of alix-binding simian immunodeficiency virus SIV sme543 and SIV mac239 type 3 L domains

Journal of Virology

Volumn 85, Issue 21, 2011, Pages 11532-11537

  Bello, Nana F ^a   Wu, Fan ^a   Sette, Paola ^a   Dussupt, Vincent ^a   Hirsch, Vanessa M ^a   Bouamr, Fadila ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIX PROTEIN; BINDING PROTEIN; GAG PROTEIN; LEUCINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CONTROLLED STUDY; GENE MUTATION; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; SIMIAN IMMUNODEFICIENCY VIRUS;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; CALCIUM-BINDING PROTEINS; HOST-PATHOGEN INTERACTIONS; LEUCINE; PROTEIN BINDING; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL PROTEINS; VIRUS RELEASE;

PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 80055114108     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05284-11     Document Type: Note

References (30)

1. Bieniasz, P. D. 2009. The cell biology of HIV-1 virion genesis. Cell Host Microbe 5:550-558.
2. Bieniasz, P. D. 2006. Late budding domains and host proteins in enveloped virus release. Virology 344:55-63.
3. Bouamr, F., et al. 2007. The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production. J. Virol. 81:2909-2922.
4. Bouamr, F., et al. 2003. PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected]. J. Virol. 77:11882-11895.
5. Demirov, D. G., and E. O. Freed. 2004. Retrovirus budding. Virus Res. 106:87-102.
6. Garrus, J. E., et al. 2001. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107:55-65.
7. Gottwein, E., et al. 2003. The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release. J. Virol. 77:9474-9485.
8. Heidecker, G., P. A. Lloyd, K. Fox, K. Nagashima, and D. Derse. 2004. Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release. J. Virol. 78:6636-6648.
9. Hirsch, V., et al. 1997. A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3. J. Virol. 71:1608-1620.
10. Ikeda, H., and T. K. Kerppola. 2008. Lysosomal localization of ubiquitinated Jun requires multiple determinants in a lysine-27-linked polyubiquitin conjugate. Mol. Biol. Cell 19:4588-4601.
11. Jouvenet, N., M. Zhadina, P. D. Bieniasz, and S. M. Simon. 2011. Dynamics of ESCRT protein recruitment during retroviral assembly. Nat. Cell Biol. 13:394-401.
12. + immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication. J. Virol. 82:1723-1738.
13. Martin-Serrano, J., S. W. Eastman, W. Chung, and P. D. Bieniasz. 2005. HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway. J. Cell Biol. 168:89-101.
14. Martin-Serrano, J., A. Yarovoy, D. Perez-Caballero, and P. D. Bieniasz. 2003. Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. Proc. Natl. Acad. Sci. U. S. A. 100:12414-12419.
15. Martin-Serrano, J., T. Zang, and P. D. Bieniasz. 2001. HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat. Med. 7:1313-1319.
16. Morita, E., and W. I. Sundquist. 2004. Retrovirus budding. Annu. Rev. Cell Dev. Biol. 20:395-425.
17. Munshi, U. M., J. Kim, K. Nagashima, J. H. Hurley, and E. O. Freed. 2007. An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains. J. Biol. Chem. 282:3847-3855.
18. Pornillos, O., et al. 2002. Structure and functional interactions of the Tsg101 UEV domain. EMBO J. 21:2397-2406.
19. Pornillos, O., J. E. Garrus, and W. I. Sundquist. 2002. Mechanisms of enveloped RNA virus budding. Trends Cell Biol. 12:569-579.
20. Pornillos, O., et al. 2003. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J. Cell Biol. 162:425-434.
21. Segura-Morales, C., et al. 2005. Tsg101 and Alix interact with murine leukemia virus Gag and cooperate with Nedd4 ubiquitin ligases during budding. J. Biol. Chem. 280:27004-27012.
22. nL L domain motif. J. Virol. 84:8181-8192.
23. Strack, B., A. Calistri, S. Craig, E. Popova, and H. G. Gottlinger. 2003. AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell 114:689-699.
24. Stuchell-Brereton, M. D., et al. 2007. ESCRT-III recognition by VPS4 ATPases. Nature 449:740-744.
25. VerPlank, L., et al. 2001. Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc. Natl. Acad. Sci. U. S. A. 98:7724-7729.
26. von Schwedler, U. K., et al. 2003. The protein network of HIV budding. Cell 114:701-713.
27. Wang, H., N. J. Machesky, and L. M. Mansky. 2004. Both the PPPY and PTAP motifs are involved in human T-cell leukemia virus type 1 particle release. J. Virol. 78:1503-1512.
28. Wollert, T., and J. H. Hurley. 2010. Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature 464:864-869.
29. Zhai, Q., et al. 2008. Structural and functional studies of ALIX interactions with YPX(n) L late domains of HIV-1 and EIAV. Nat. Struct. Mol. Biol. 15:43-49.
30. agmTan-1. J. Virol. 85:632-637.