Investigations of hippocampal astrocytes in lipopolysaccharide-preconditioned rats in the pilocarpine model of epilepsy

Folia Histochemica et Cytobiologica

Volumn 49, Issue 2, 2011, Pages 219-224

  Jaworska Adamu, Jadwiga ^a   Dmowska, Miroslawa ^b   Cybulska, Regina ^a   Krawczyk, Aleksandra ^a   Pawlikowska Pawlega, Bozena ^b  

^a UNIVERSITY OF LIFE SCIENCES IN LUBLIN   (Poland)

^b MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

Author keywords

Astrocytes; Epilepsy; Hippocampus; Lipopolysaccharide; Rat

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL FUNCTION; CELL SHAPE; CELL STRUCTURE; CELL SWELLING; CELL ULTRASTRUCTURE; CELL VACUOLE; CONTROLLED STUDY; EPILEPSY; GLIA CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; IN VIVO CULTURE; MALE; NONHUMAN; RAT; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; HIPPOCAMPUS; PATHOLOGY; PYRAMIDAL NERVE CELL; ULTRASTRUCTURE; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; EPILEPSY; HIPPOCAMPUS; LIPOPOLYSACCHARIDES; MALE; PILOCARPINE; PYRAMIDAL CELLS; RATS; RATS, WISTAR;

EID: 80055109577     PISSN: 02398508     EISSN: 18975631     Source Type: Journal    
DOI: 10.5603/FHC.2011.0030     Document Type: Article

References (22)

1. Chen Y, Swanson RA. Astrocytes and brain injury. J Cerebr Blood Flow Metab. 2003;23:137-149.
2. Keyser JD, Mostert JP, Koch MW. Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders. J Neurol Sci. 2008;267:3-16.
3. Schwacz R. Early glial dysfunction in epilepsy. Epilepsia (Suppl. 2). 2008;49:1-2.
4. Szydłowska K, Kamińska B. Pharmacological modulation of function and viability of astrocytes as a novel neuroprotective strategy in stroke. Kosmos. 2008;57:315-329.
5. Brown DR. Neuronal release of vasoactive intestinal peptide is important to astrocytic protection of neurons from glutamate toxicity. Mol Cell Neurosci. 2000;15:465-475.
6. Rossi DJ, Brady JD, Mohr C. Astrocyte metabolism and signaling during brain ischemia. Nat Neurosci. 2008;10:1377-1386.
7. Janeczko K. The proliferative activity of astrocytes after immunoglobulin uptake in the injured mouse cerebral hemisphere. Folia Histochem Cytobiol. 1994;32:239-241.
8. Garzillo CL, Mello EAM. Characterization of reactive astrocytes in the chronic phase of the pilocarpine epilepsy. Epilepsia (Suppl). 2002;43:107-109.
9. Turski WA, Cavalheiro EA, Bortolotto ZA, Mello LM, Schwarz M, Turski L. Seizures produced by pilocarpine in mice: a behavioural, electroencephalographic and and morphological analysis. Brain Res. 1984;321:237-253.
10. Turski WA, Cavalheiro EA, Schwarz M, Czuczwar SJ, Kleinrok Z, Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res. 1983;9:315-335.
11. Klitgaard H, Matagne A, Vneste-Goemaere J, Margineanu DG. Pilocarpine-induced epileptogenesis in the rat: impact of initial duration of status epilepticus on electrophysiological and neuropathological alterations. Epilepsy Res. 2002;51:93-107.
12. Konig FR, Klippel RA. The rat brain. A stereotaxic atlas of the forebrain and lower parts of the brain stem. RR Krieger, Huntington NY 1970.
13. O'Shea RD, Lau ChL, Farso MC et al. Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: evidence for delayed up-regulation and redistribution of GLT-1. Neurochem Int. 2006;48:604-610.
14. Takuma K, Baba A, Matsuda T. Astrocytes apoptosis: implications for neuroprotection. Progress Neurobiol. 2004; 72:111-127.
15. Lieberman AP, Pitha PM, Shin HS, Shin ML. Production of tumor necrotic factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci. 1999;86:6348-6352.
16. Hu S, Martella A, Anderson WR, Chao ChC. Role of cytokines in lipopolysaccharide-induced functional and structural abnormalities of astrocytes. Glia. 2004;10:227-234.
17. Khurgel M, Switzer RC 3rd, Teskey GC, Spiller AE, Go I. Activation of astrocytes during epileptogenesis in the absence of neuronal degeneration. Neurobiol Dis. 1995;2: 23-35.
18. Rogowski MA. Astrocytes get in the act in the epilepsy. Nat Med. 2005;11:919-920.
19. Pera J. Hartowanie przez niedokrwienie. Aktualności neurologiczne (sympozjum udar mozgu). 2006;2:17-25.
20. Dirnagl U, Piller J. Focal cerebral ischemia: the multifaceted role of glial cells. Neuroglia, Oxford University Press, 2005.
21. Babb TL, Mathern GW, Pretorius JK et al. Astrocytes may contribute to the latent period in progressive neurons loss, axon sprouting, and chronic seizure in rat kainate hippocampal epilepsy. Epilepsy Res Suppl. 1996;12:343-354.
22. Shapiro LA, Wang L, Ribak ChE. Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats. Epilepsia. 2008;49:33-41.