The differential effects of aligned electrospun PHBHHx fibers on adipogenic and osteogenic potential of MSCs through the regulation of PPARγ signaling

Biomaterials

Volumn 33, Issue 2, 2012, Pages 485-493

  Wang, Yang ^a,b   Gao, Rui ^a   Wang, Pei Pei ^a   Jian, Jia ^b   Jiang, Xian Li ^a   Yan, Chao ^a   Lin, Xiao ^a   Wu, Li ^a   Chen, Guo Qiang ^b   Wu, Qiong ^a  

^a TSINGHUA UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Electrospun fibers; Mesenchymal stem cells; Osteogenic differentiation; Polyhydroxyalkanoates; PPAR

Indexed keywords

ACTIN CYTOSKELETON; ADIPOGENESIS; ADIPOGENIC; ALIGNED FIBERS; BONE TISSUE ENGINEERING; CELL-SUBSTRATE INTERACTIONS; DIFFERENTIAL EFFECT; DIFFERENTIALLY EXPRESSED GENE; DOWN-REGULATION; ELECTROSPINNING TECHNIQUES; ELECTROSPUN FIBERS; ELECTROSPUNS; FIBER ALIGNMENT; FIBROUS SCAFFOLDS; FIBROUS STRUCTURES; MESENCHYMAL STEM CELL; MINERALIZED COLLAGEN; OSTEOGENESIS; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTEOGENIC POTENTIAL; POLYHYDROXYALKANOATES; RANDOM GROUPS; SIGNALING PATHWAYS; TENSION STRESS; TRANSCRIPTOMES; WESTERN BLOTTING;

ADHESION; ALIGNMENT; BONE; CELL ADHESION; CELL CULTURE; ELECTROSPINNING; FLOWCHARTING; GENES; PHOSPHORYLATION; PROTEINS; SCAFFOLDS (BIOLOGY); SIGNALING; STEM CELLS; TISSUE;

FIBERS;

ACTIN; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTOME;

ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; CELL ADHESION; CELL DIFFERENTIATION; CELL MEMBRANE POTENTIAL; CYTOSKELETON; ELECTROSPINNING; ENZYME PHOSPHORYLATION; FIBER; GENE EXPRESSION; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; YOUNG MODULUS;

3-HYDROXYBUTYRIC ACID; ADIPOGENESIS; ANIMALS; CAPROATES; CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION PROFILING; MESENCHYMAL STROMAL CELLS; MICROARRAY ANALYSIS; MICROSCOPY, ELECTRON, SCANNING; OSTEOGENESIS; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TRANSCRIPTOME;

EID: 80055107305     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.089     Document Type: Article

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