One-pot synthesis of functionalized spirobenzofuranones via MCR involving 3-cyanochromones

Journal of Organic Chemistry

Volumn 76, Issue 21, 2011, Pages 9008-9014

  Zarganes Tzitzikas, Tryfon ^a   Terzidis, Michael A ^a   Stephanidou Stephanatou, Julia ^a   Tsoleridis, Constantinos A ^a   Kostakis, George E ^b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BASIS SETS; CHROMONES; DFT CALCULATION; FUNCTIONALIZED; INTERMEDIATE PRODUCT; ISOCYANIDES; NMR CHEMICAL SHIFTS; ONE-POT SYNTHESIS; TRANSITION STRUCTURES; ZWITTERIONIC INTERMEDIATE;

CYANIDES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION INTERMEDIATES;

SYNTHESIS (CHEMICAL);

3 BENZOFURANONE DERIVATIVE; 3 CYANOCHROMONE; AMPHOLYTE; CHROMONE DERIVATIVE; DIETHYL 4' (TERT BUTYLAMINO) 5 CHLORO 5' CYANO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 4' (TERT BUTYLAMINO) 5' CYANO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 4' (TERT BUTYLAMINO) 5' CYANO 5 METHYL 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 4' (TERT BUTYLAMINO) 5' CYANO 5,7 DICHLORO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 5 CHLORO 5' CYANO 4' (CYCLOHEXYLAMINO) 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 5' CYANO 4' (CYCLOHEXYLAMINO) 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIETHYL 5' CYANO 4' (CYCLOHEXYLAMINO) 5 METHYL 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIMETHYL 4' (TERT BUTYLAMINO) 5 CHLORO 5' CYANO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIMETHYL 4' (TERT BUTYLAMINO) 5' CYANO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIMETHYL 4' (TERT BUTYLAMINO) 5' CYANO 5 METHYL 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; DIMETHYL 4' (TERT BUTYLAMINO) 5' CYANO 5,6 DIMETHYL 3 OXO 3H SPIRO; DIMETHYL 5' CYANO 4' (CYCLOHEXYLAMINO) 5,7 DICHLORO 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2',3' DICARBOXYLATE; METHYL 5' CYANO 4' (CYCLOHEXYLAMINO) 3 OXO 3H SPIRO(1 BENZOFURAN 2,1' CYCLOPENTA[2',4']DIENE) 2' CARBOXYLATE; SPIROBENZOFURANONE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL PARAMETERS; CHEMICAL REACTION; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; DRUG STRUCTURE; DRUG SYNTHESIS; GEOMETRY; MULTICOMPONENT REACTION; NUCLEAR MAGNETIC RESONANCE; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; REGIOSELECTIVITY;

EID: 80055091303     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo201732g     Document Type: Article

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