The role of vitamin D, estrogen, calcium sensing receptor genotypes and serum calcium in the pathogenesis of prostate cancer

Canadian Journal of Urology

Volumn 18, Issue 3, 2011, Pages 5710-5716

  Szendroi, Attila ^a   Speer, Gabor ^b   Tabak, Adam ^b,c   Kosa, Janos P ^b   Nyírády, Peter ^a   Majoros, Attila ^a   Romics, Imre ^a   Lakatos, Peter ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Calcium sensing receptor; Estrogen alpha receptor; Prostate cancer; Serum calcium; vitamin D receptor

Indexed keywords

CALCITRIOL RECEPTOR; CALCIUM; CALCIUM SENSING RECEPTOR; ESTROGEN RECEPTOR;

AGED; ARTICLE; BLOOD; CASE CONTROL STUDY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PROSTATE TUMOR; RISK FACTOR; STATISTICAL MODEL;

AGED; AGED, 80 AND OVER; CALCIUM; CASE-CONTROL STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROSTATIC NEOPLASMS; RECEPTORS, CALCITRIOL; RECEPTORS, CALCIUM-SENSING; RECEPTORS, ESTROGEN; RISK FACTORS;

EID: 80055086901     PISSN: 11959479     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010;60(5):277-300.
2. Schulz WA, Burchardt M, Cronauer MV. Molecular biology of prostate cancer. Mol Hum Reprod 2003;9(8):437-448.
3. Platz EA, Giovannucci E. The epidemiology of sex steroid hormones and their signaling and metabolic pathways int he etiology of prostate cancer. J Steroid Biochem Mol Biol 2004;92(4):237-253.
4. Hernandez J, Balic I, Johnson-Pais TL et al. Association between an estrogen receptor alpha gene polymorphism and the risk of prostate cancer in black men. J Urol 2006;175(2):523-527.
5. González-Zuloeta Ladd AM, Vásquez AA, Rivadeneira F et al. Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk. Breast Cancer Res Treat 2008;107(3):415-419.
6. Ushiyama T, Ueyama H, Inoue K, Nishioka J, Ohkubo I, Hukuda S. Estrogen receptor gene polymorphism and generalisated osteoarthritis. J Rheumatol 1998;25(1):134-137.
7. Kobayashi S, Inoue S, Hosoi T, Ouchi Y, Shiraki M, Orimo H. Association of bone mineral density with polymorphism of estrogen receptor gene. J Bone Miner Res 1996;11(3):306-311.
8. Liel Y, Shany S, Smirnoff P, Schwartz B. Estrogen increases 1,25 dihydroxivitamin D receptors expression and bioresponse in the rat duodenal mucosa. Endocrinology 1999;140(1):280-285.
9. Mucci LA, Spiegelman D. Vitamin D and prostate cancer risk - a less sunny outlook? J Natl Cancer Inst 2008;100(11):759-761.
10. Larriba MJ, Valle N, Alvarez S, Muñoz A. Vitamin D3 and colorectal cancer. Adv Exp Med Biol 2008;617(1):271-280.
11. Mikhak B, Hunter DJ, Spiegelman D, Platz E, Hollis BW, Giovannucci E. Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-Dihydroxyvitamin D, and prostate cancer risk. Prostate 2007;67(9):911-923.
12. Berndt SI, Dodson JL, Huang WI, Nicodemus KK. A systematic review of vitamin D receptor gene polymorphisms and prostate cancer risk. J Urol 2006;175(5):1613-1623.
13. Lin KI, Chattopadhyay N, Bai M et al. Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor. Biochem Biophys Res Comm 1998;249(2):325-331.
14. Whitfield JB, Martin NG. The effects of inheritance on constituents of plasma: a twin study on some biochemical variables. Ann Clin Biochem 1994;21(3):176-183.
15. Brown EM, Pollack M, Hebert SC. The extracellular calciumsensing receptor: its role in health and disease. Ann Rev Med 1998;49(1):15-29.
16. Cole DE, Peltekova VD, Rubin LA et al. A986S polymorphism of the calcium sensing receptor and circulating calcium concentrations. Lancet 1999;353(9147):112-115.
17. Nagelkerke, NJD. A note on a general definition of the coefficient of determination. Biometrika 1991;78(1):691-692.
18. Gsur A, Madersbacher S, Haidinger G et al. Vitamin D receptor gene polymorphism and prostate cancer risk. Prostate 2002;51(1):30-34.
19. John EM, Schwartz GG, Koo J, Berg DVD, Ingles SA. Sun exposure, vitamin D receptor gene polymorphism, and risk of advanced prostate cancer. Cancer Res 2005;65(12):5470-5479.
20. Cicek MS, Liu X, Schumacher FR, Casey G, Witte JS. Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2006;15(12):2549-2552.
21. Gennari L, Becherini L, Masi L et al. Vitamin D receptor genotypes and intestinal calcium absorption in postmenopausal women. Calcif Tissue Int 1997;61(6):460-463.
22. Yang K, Lamprecht SA, Shinozaki H et al. Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice. J Nutr 2008;138(9):1658-1663.
23. Lee HJ, Ji Y, Paul S, Maehr H, Uskokovic M, Suh N. Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha. Cancer Res 2007;67(24)11840-11847.
24. Krishnan AV, Moreno J, Nonn L et al. Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer. J Steroid Biochem Mol Biol 2007;103(3-5):694-702.
25. Castagnetta L, Granata OM, Polito L, Blasi L, Cannella S, Carruba G. Different conversion metabolic rates of testosterone are assotiated to hormone-sensitive status and response of human prostate cancer cells. J Steroid Biochem Mol Biol 1994;49(4-6):351-357.
26. Royuela M, de Miguel MP, Bethencourt FR et al. Estrogen receptors alpha and beta in the normal, hyperplastic and carcinomatous human prostate. J Endocrinol 2001;168(3):445-447.
27. Latil A, Bièche I, Vidaud D et al. Evaluation of androgen, estrogen (ER alpha and beta) and progesterone receptor expression in human prostate cancer by real time quantitative reverse transcription-polymerase chain reaction assays. Cancer Res 2001;61(5):1919-1926.
28. Prins GS, Woodham C, Lepinske M, Birch L. Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with andronen receptor expression in the separate prostate lobes of adult rat. Endocrinology 1993;132(6):1801-1809.
29. Modugno F, Weissfeld JL, Trump DL et al. Allelic variants of aromatase and the androgen and estrogen receptors: toward a multigenic model of prostate cancer risk. Clin Cancer Res 2001;7(10):3092-3096.
30. Ming Yin, Sheng Wei, Qingyi Wei. Vitamin D receptor genetic polymorphisms and prostate cancer risk: a meta-analysis of 36 published studies. Int J Clin Exp Med 2009;2(2):159-175.