Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo

NeuroToxicology

Volumn 32, Issue 6, 2011, Pages 981-985

  Kim, Kyung Ho ^a,b   Pessah, Isaac N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

Excitotoxicity; GABA A receptor; Hippocampal slice; Hippocampus; Microelectrode array; Non coplanar PCBs; Picrotoxin; Seizure activity

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AROCLOR 1254; PICROTOXIN; POLYCHLORINATED BIPHENYL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN PERFUSION; BRAIN SLICE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EVOKED RESPONSE; EX VIVO STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; EXCITOTOXICITY; HIPPOCAMPAL CA1 REGION; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; SEIZURE SUSCEPTIBILITY; STRATUM RADIATUM;

ANIMALS; CHLORODIPHENYL (54% CHLORINE); ELECTRIC STIMULATION; ENVIRONMENTAL POLLUTANTS; EVOKED POTENTIALS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GABA-A RECEPTOR ANTAGONISTS; HIPPOCAMPUS; MATERNAL EXPOSURE; NEURONAL PLASTICITY; PICROTOXIN; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; SYNAPTIC TRANSMISSION; TIME FACTORS;

RATTUS;

EID: 80055086243     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2011.04.004     Document Type: Article

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