Clinical results of boron neutron capture therapy (BNCT) for glioblastoma

Applied Radiation and Isotopes

Volumn 69, Issue 12, 2011, Pages 1823-1825

  Kageji, T ^a   Mizobuchi, Y ^a   Nagahiro, S ^a   Nakagawa, Y ^b   Kumada, H ^c  

^a National Hospital Organization   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

BNCT; Glioblastoma; Survival

Indexed keywords

BNCT; BORON NEUTRON CAPTURE THERAPY; CLINICAL OUTCOME; CONVENTIONAL TREATMENTS; GLIOBLASTOMAS; HISTORICAL DATA; INTRA-OPERATIVE; MEDIAN SURVIVAL; SURVIVAL; SURVIVAL RATE;

BORON; BORON COMPOUNDS; CHEMOTHERAPY;

PATIENT TREATMENT;

4 BORONOPHENYLALANINE; BOROCAPTATE;

ACUTE DISEASE; ADULT; ARTICLE; CANCER SURVIVAL; CASE REPORT; DRUG BLOOD LEVEL; FEMALE; GLIOBLASTOMA; HUMAN; INTRAOPERATIVE PERIOD; MALE; NEUTRON CAPTURE THERAPY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; SURVIVAL RATE; SURVIVAL TIME; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; GLIOBLASTOMA; HUMANS; MIDDLE AGED; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 80055083183     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2011.05.029     Document Type: Article

References (6)

1. Hatanaka H., Nakagawa Y. Clinical results of long-surviving brain tumor patients who underwent boron neutron capture therapy. Int. J. Radiat. Oncol. Biol. Phys. 1994, 28:1061-1066.
2. Nakagawa Y., Hatanaka H. Boron neutron capture therapy-clinical brain tumor study. J. Neuro-Oncol. 1997, 33:105-115.
3. Nakagawa Y., Pooh K., Kobayshi T., Kageji T., Uyama S., Matsumura A., Kumada H. Clinical review of Japanese experience with boron neutron capture therapy and a proposed strategy using epithermal neutron beams. J. Neuro-Oncol. 2003, 62:87-99.
4. Kageji T., Nagahiro S., Mizobuchi Y., Toi H., Nakagawa Y., Kumada H. Radiation injury of boron neutron capture therapy using mized epithermal- and thermal neutron beams in patients with malignant glioma. Appl. Radiat. Isot. 2004, 61:1063-1067.
5. Kageji T., Nagahiro S., Matsuzaki K., Mizobuchi Y., Toi H., Nakagawa Y., Kumada H. Boron neutron capture therapy using mixed epthermal and thermal neutron beams in patients with malignant glioma-correlation between radiation dose and radiation injury and clinical outcome. Int. J. Radiat. Oncol. Biol. Phys. 2006, 65:1446-1455.
6. Stupp R., Hegi M.E., Mason W.P., van den Bent M.J. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomized phase III study: 5-year analysis on the EORTC-NCIC trial. Lancet Oncol. 2009, 10(5):459-466.