Reference values for aldosterone-renin ratios in normotensive individuals and effect of changes in dietary sodium consumption

Clinical Chemistry

Volumn 57, Issue 11, 2011, Pages 1607-1611

  Kerstens, Michiel N ^a   Muller Kobold, Anneke C ^a   Volmer, Marcel ^a   Koerts, Jan ^a   Sluiter, Wim J ^a   Dullaart, Robin P F ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; RENIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; FEMALE; HUMAN; MALE; NORMAL HUMAN; PLASMA RENIN ACTIVITY; REFERENCE VALUE; SALT LOADING; SEX DIFFERENCE; SODIUM INTAKE;

ADULT; AGED; ALDOSTERONE; BLOOD PRESSURE; FEMALE; HUMANS; MALE; MIDDLE AGED; REFERENCE VALUES; RENIN; SEX FACTORS; SODIUM, DIETARY;

EID: 80055072249     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.165662     Document Type: Article

References (19)

1. Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, et al. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2008;93:3266-81.
2. Montori VM, Young WF Jr. Use of plasma aldosterone concentration-to- plasma renin activity ratio as a screening test for primary aldosteronism. A systematic review of the literature. Endocrinol Metab Clin North Am 2002;31:619-32. (Pubitemid 35006613)
3. Sealey JE, Gordon RD, Mantero F. Plasma renin and aldosterone measurements in low renin hypertensive states. Trends Endocrinol Metab 2005;16:86-91. (Pubitemid 40432456)
4. Schirpenbach C, Seiler L, Maser-Gluth C, Beuschlein F, Reincke M, Bidlingmaier M. Automated chemiluminescence-immunoassay for aldosterone during dynamic testing: comparison to radioimmunoassays with and without extraction steps. Clin Chem 2006;52:1749-55. (Pubitemid 44330710)
5. Derkx FHM, de Bruin RJA, van Gool JMG, van den Hoek MJ, Beerendonk CCM, Rosmalen F, et al. Clinical validation of renin monoclonal antibody-based sandwich assays of renin and prorenin, and use of renin inhibitor to enhance prorenin immunoreactivity. Clin Chem 1996;42:1051-63. (Pubitemid 26231411)
6. de Bruin RA, Bouhuizen A, Diederich S, Perschel FH, Boomsma F, Deinum J. Validation of a new automated renin assay. Clin Chem 2004;50:2111-6. (Pubitemid 39425849)
7. Hannemann A, Friedrich N, Ludemann J, Volzke H, Rettig R, Peters J, et al. Reference intervals for aldosterone, renin, and the aldosterone-to-renin ratio in the population-based Study of Health in Pomerania (SHIP-1). Horm Metab Res 2010;42:392-9.
8. Komukai K, Mochizuki S, Yoshimura M. Gender and the renin-angiotensin- aldosterone system. Fundam Clin Pharmacol 2010;24:687-98.
9. Campbell DJ, Nussberger J, Stowasser M, Danser AH, Morganti A, Frandsen E, et al. Activity assays and immunoassays for plasma renin and prorenin: information provided and precautions necessary for accurate measurement. Clin Chem 2009;55:867-77.
10. Ahmed AH, Gordon RD, Taylor PJ, Ward G, Pimenta E, Stowasser M. Are women more at risk of false-positive primary aldosteronism screening and unnecessary suppression testing than men? J Clin Endocrinol Metab 2011;96:E340-6.
11. Pizzolo F, Raffaelli R, Memmo A, Chiecchi L, Pavan C, Guarini P, et al. Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism. J Hypertens 2010;28:135-42.
12. Taylor PJ, Cooper DP, Gordon RD, Stowasser M. Measurement of aldosterone in human plasma by semiautomated HPLC-tandem mass spectrometry. Clin Chem 2009;55:1155-62.
13. Szmuilowicz ED, Adler GK, Williams JS, Green DE, Yao TM, Hopkins PN, et al. Relationship between aldosterone and progesterone in the human menstrual cycle. J Clin Endocrinol Metab 2006;91:3981-7. (Pubitemid 44536873)
14. Hegstad R, Brown RD, Jiang NS, Kao P, Weinshilboum RM, Strong C, et al. Aging and aldosterone. Am J Med 1983;74:442-8. (Pubitemid 13157646)
15. Crane MG, Harris JJ. Effect of aging on renin activity and aldosterone excretion. J Lab Clin Med 1976;87:947-59.
16. Tsunoda K, Abe K, Goto T, Yasujima M, Sato M, Omata K, et al. Effect of age on the reninangiotensin-aldosterone system in normal subjects: simultaneous measurement of active and inactive renin, renin substrate, and aldosterone in plasma. J Clin Endocrinol Metab 1986;62:384-9. (Pubitemid 16121572)
17. Trenkel S, Seifarth C, Schobel H, Hahn EG, Hensen J. Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism. Exp Clin Endocrinol Diabetes 2002;110:80-5. (Pubitemid 34296857)
18. Perschel FH, Schemer R, Seiler L, Reincke M, Deinum J, Maser-Gluth C, et al. Rapid screening test for primary hyperaldosteronism: ratio of plasma aldosterone to renin concentration determined by fully automated chemiluminescence immunoassays. Clin Chem 2004;50:1650-5. (Pubitemid 39121234)
19. Westerdahl C, Bergenfelz A, Isaksson A, Wihl A, Nerbrand C, Valdemarsson S. High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden. Scand J Prim Health Care 2006;24:154-9. (Pubitemid 44272851)