Guidelines for Pubertal Suspension and Gender Reassignment for Transgender Adolescents

Child and Adolescent Psychiatric Clinics of North America

Volumn 20, Issue 4, 2011, Pages 725-732

  Hembree, Wylie C ^a  

^a Columbia University Medical Center ^*  (United States)

Author keywords

Estrogen; Gender identity disorder; Gonadotropin releasing hormone agonist; Puberty Suppression; Testosterone

Indexed keywords

ANDROGEN; ESTRADIOL; ESTROGEN; GESTAGEN; GONADORELIN DERIVATIVE; SEX HORMONE; TESTOSTERONE ESTER;

ACNE; ADOLESCENT; AGE; BEHAVIOR CHANGE; BONE MATURATION; BREAST DISEASE; CLINICAL DECISION MAKING; CLINICAL FEATURE; FERTILITY; GALACTORRHEA; GROWTH ACCELERATION; HORMONAL THERAPY; HOT FLUSH; HUMAN; HYPERPROLACTINEMIA; LOW DRUG DOSE; MASTECTOMY; METABOLIC DISORDER; PHYSICAL EXAMINATION; PRACTICE GUIDELINE; PRIORITY JOURNAL; PUBERTAL SUSPENSION; REVIEW; SEX REASSIGNMENT; SIDE EFFECT; SPOTTING; TRANSSEXUALISM; UROLOGIC SURGERY;

ADOLESCENT; GENDER IDENTITY; GONADAL STEROID HORMONES; GONADOTROPIN-RELEASING HORMONE; GUIDELINES AS TOPIC; HUMANS; PUBERTY; SEX REASSIGNMENT PROCEDURES; SEX REASSIGNMENT SURGERY; TRANSSEXUALISM;

EID: 80055069938     PISSN: 10564993     EISSN: 15580490     Source Type: Journal    
DOI: 10.1016/j.chc.2011.08.004     Document Type: Review

References (21)

1. Cohen-Kettenis P.T., Delemarre-van de Waal H.A., Gooren L.J. The treatment of adolescent transsexuals: changing insights. J Sex Med 2008, 5:1892-1897.
2. Cohen-Kettenis P.T., van Goozen S.H. Sex reassignment of adolescent transsexuals: a follow-up study. J Am Acad Child Adolesc Psychiatry 1997, 36:263-271.
3. Diagnostic and statistical manual of mental disorders 2000, American Psychiatric Association (APA), Author, Washington (DC).
4. Delemarre-Van de Waal H.A., Cohen-Kettenis P.T. Clinical Management of gender identity disorder in adolescents: a protocol on psychological and paediatric endocrinology aspects. Eur J Endocrinol 2006, 155(Suppl 1):S131-S137.
5. Hembree W.C., Cohen-Kettenis P.T., Delemarre-van de Waal H.A., et al. Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2009, 94:3132-3154.
6. Drummond K.D., Bradley S.J., Peterson-Bidali M., et al. A follow-up study of girls with gender identity disorder. Dev Psychol 2008, 44:34-45.
7. Zucker K.J. Gender identity disorder in children and adolescents. Annu Rev Clin Psychol 2005, 1:467-492.
8. de Vries A.L.C., Steensma T.D., Doreleijers T.A.H., et al. Puberty suppression in adolescents with gender identity disorder: a prospective follow-up study. J Sex Med 2011, 8:2276-2283.
9. Delemarre E.M., Felius B., Delemarre-van de Waal H.A. Inducing puberty. Eur J Endocrinol 2008, 159:S9-S15.
10. DiVasta A.D., Gordon C.M. Hormone replacement therapy for the adolescent patient. Ann N Y Acad Sci 2008, 1135:204-211.
11. Sadaghi-Nejad A., Kaplan S.L., Grumbach M.M. The effect of medroxyprogesterone acetate on adrenocortical function in children with precocious puberty. J Pediatr 1971, 78:616-624.
12. Jewelewicz R., Dyrenfurth I., Ferin M., et al. Gonadotropin, estrogen and progesterone response to long term gonadotropin-releasing hormone infusion at various stages of the menstrual cycle. J Clin Endocrinol Metab 1977, 45:662-667.
13. Plosker G.L., Brogden R.N. Leuprorelin: a review of its pharmacology and therapeutic use in prostate cancer, endometriosis and other sex hormone-related disorders. Drugs 1994, 48:930-967.
14. Bukulmez O. Biochemistry, molecular biology and cell biology of gonadotropin-releasing hormone antagonists. Curr Opin Obstet Gynecol 2011, 23:238-244.
15. Meyer M., Bockting W., Cohen-Kettenis P.T., et al. Harry Benjamin International Gender Dysphoria Association's standards of care for gender identity disorder, 6th version. International Journal of Transgenderism 2001, 5:1. Accessed August 18, 2011. http://www.wpath.org/publications%20standards.cfm.
16. Bardin C.W., Hembree W.C., Lipsett M.B. Suppression of testosterone and androstenedione production rates with dexamethasone in women with idiopathic hirsutism and polycystic ovaries. J Clin Endocrinol Metab 1968, 28:1300-1306.
17. Olsen J., Forbes C., Belzer M. Management of the transgender adolescent. Arch Pediatr Adolesc Med 2011, 165. 17117-6.
18. Kreukels B.P.C., Cohen-Kettenis P.T. Puberty suppression in gender identity disorder: the Amsterdam experience. Nature Rev Endocrinol 2011, 7:466-472.
19. Asscheman H., Giltay R., Megens A.J., et al. A long-term follow-up study of mortality in transsexuals receiving treatment with cross-sex steroids. Eur J Endocrinol 2011, 164:635-642.
20. Gooren L.J. Care of transsexual persons. N Engl J Med 2011, 364:1251-1257.
21. Houk C.P., Lee P.A. The diagnosis and care of transsexual children and adolescents: a pediatric endocrinologist perspective. J Pediatr Endocrinol Metab 2006, 19:103-109.