메뉴 건너뛰기




Volumn 8, Issue 3, 2011, Pages 226-232

Acute study of clinical effectiveness of nesiritide in decompensated heart failure: Nesiritide redux

Author keywords

Acute decompensated heart failure; ASCEND HF; Dyspnea; Evidence based guidelines; Heart failure; Hospital readmission; Hypertension; Hypotension; Mortality; Nesiritide; Randomized controlled trial; Renal dysfunction

Indexed keywords

DOBUTAMINE; GLYCERYL TRINITRATE; MILRINONE; NESIRITIDE; NITROPRUSSIDE SODIUM; PLACEBO;

EID: 80055060618     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-011-0066-4     Document Type: Article
Times cited : (12)

References (54)
  • 1
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2008 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Rosamond W, Flegal K, Furie K, et al. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2008;117:e25-e146.
    • (2008) Circulation , vol.117
    • Rosamond, W.1    Flegal, K.2    Furie, K.3
  • 2
    • 0034110023 scopus 로고    scopus 로고
    • Epidemiology, aetiology, and prognosis of heart failure
    • McMurray JJ, Stewart S. Epidemiology, aetiology, and prognosis of heart failure. Heart. 2000;83:596-602. (Pubitemid 30316742)
    • (2000) Heart , vol.83 , Issue.5 , pp. 596-602
    • McMurray, J.J.1    Stewart, S.2
  • 3
    • 33645794744 scopus 로고    scopus 로고
    • An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with heart failure
    • Krumholz HM, Wang Y, Mattera JA, et al. An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with heart failure. Circulation. 2006;113:1693-1701.
    • (2006) Circulation , vol.113 , pp. 1693-1701
    • Krumholz, H.M.1    Wang, Y.2    Mattera, J.A.3
  • 5
    • 14844291419 scopus 로고    scopus 로고
    • Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    • DOI 10.1016/j.ahj.2004.08.005
    • Adams Jr KF, Fonarow GC, Emerman CL, et al. Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005;149:209-216. (Pubitemid 40348525)
    • (2005) American Heart Journal , vol.149 , Issue.2 , pp. 209-216
    • Adams Jr., K.F.1    Fonarow, G.C.2    Emerman, C.L.3    LeJemtel, T.H.4    Costanzo, M.R.5    Abraham, W.T.6    Berkowitz, R.L.7    Galvao, M.8    Horton, D.P.9
  • 8
    • 33745881351 scopus 로고    scopus 로고
    • National trends in outcomes among elderly patients with heart failure
    • Kosiborod M, Lichtman JH, Heidenreich PA, et al. National trends in outcomes among elderly patients with heart failure. Am J Med. 2006;119:616-617.
    • (2006) Am J Med. , vol.119 , pp. 616-617
    • Kosiborod, M.1    Lichtman, J.H.2    Heidenreich, P.A.3
  • 9
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics-2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113:e85-e151.
    • (2006) Circulation , vol.113
    • Thom, T.1    Haase, N.2    Rosamond, W.3
  • 10
    • 29544447206 scopus 로고    scopus 로고
    • Acute Pulmonary Edema
    • DOI 10.1056/NEJMcp052699
    • Ware LB, Matthay MA. Clinical practice. Acute pulmonary edema. N Engl J Med. 2005;353:2788-2796. (Pubitemid 43016818)
    • (2005) New England Journal of Medicine , vol.353 , Issue.26 , pp. 2788-2796
    • Ware, L.B.1    Matthay, M.A.2
  • 11
  • 12
    • 0033673453 scopus 로고    scopus 로고
    • Freedom from congestion predicts good survival despite previous class IV symptoms of heart failure
    • Lucas C, Johnson W, Hamilton MA, et al. Freedom from congestion predicts good survival despite previous class IV symptoms of heart failure. Am Heart J. 2000;140:840-847.
    • (2000) Am Heart J. , vol.140 , pp. 840-847
    • Lucas, C.1    Johnson, W.2    Hamilton, M.A.3
  • 15
    • 80055026095 scopus 로고    scopus 로고
    • In-hospital brain natriuretic peptide and N-terminal prohormone brain natriuretic peptide variations are predictors of short-term and long-term outcome in acute decompensated heart failure
    • Di Somma S, Magrini L, Ferri E. In-hospital brain natriuretic peptide and N-terminal prohormone brain natriuretic peptide variations are predictors of short-term and long-term outcome in acute decompensated heart failure. Crit Care. 2011; 15(1):116.
    • (2011) Crit Care. , vol.15 , Issue.1 , pp. 116
    • Di Somma, S.1    Magrini, L.2    Ferri, E.3
  • 16
    • 78751694682 scopus 로고    scopus 로고
    • Meta-analysis: Effect of B-type natriuretic peptide testing on clinical outcomes in patients with acute dyspnea in the emergency setting
    • Lam LL, Cameron PA, Schneider HG, et al. Meta-analysis: effect of B-type natriuretic peptide testing on clinical outcomes in patients with acute dyspnea in the emergency setting. Ann Intern Med. 2010;153(11):728-735.
    • (2010) Ann Intern Med. , vol.153 , Issue.11 , pp. 728-735
    • Lam, L.L.1    Cameron, P.A.2    Schneider, H.G.3
  • 17
    • 77953401339 scopus 로고    scopus 로고
    • In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: The Italian RED Study
    • Di Somma S, Magrini L, Pittoni V, et al. In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study. Crit Care. 2010;14(3):R116.
    • (2010) Crit Care. , vol.14 , Issue.3
    • Di Somma, S.1    Magrini, L.2    Pittoni, V.3
  • 18
    • 77955888055 scopus 로고    scopus 로고
    • Natriuretic peptides (BNP and NT-proBNP): Measurement and relevance in heart failure
    • Palazzuoli A, Gallotta M, Quatrini I, et al. Natriuretic peptides (BNP and NT-proBNP): measurement and relevance in heart failure. Vasc Health Risk Manag. 2010;6:411-418.
    • (2010) Vasc Health Risk Manag. , vol.6 , pp. 411-418
    • Palazzuoli, A.1    Gallotta, M.2    Quatrini, I.3
  • 19
    • 16344389882 scopus 로고    scopus 로고
    • A review of the renal and neurohormonal effects of Btype natriuretic peptide
    • Burger AJ. A review of the renal and neurohormonal effects of Btype natriuretic peptide. Congest Heart Fail. 2005;11(1):30-38.
    • (2005) Congest Heart Fail. , vol.11 , Issue.1 , pp. 30-38
    • Burger, A.J.1
  • 21
    • 0036082757 scopus 로고    scopus 로고
    • Nesiritide: Review of clinical pharmacology and role in heart failure management
    • Cheng JW. Nesiritide: review of clinical pharmacology and role in heart failure management. Heart Dis. 2002;4(3):199-203. (Pubitemid 34670488)
    • (2002) Heart Disease , vol.4 , Issue.3 , pp. 199-203
    • Cheng, J.W.M.1
  • 22
    • 0030481630 scopus 로고    scopus 로고
    • Hemodynamic and renal excretory effects of human brain natriuretic peptide infusion in patients with congestive heart failure: A double-blind, placebo-controlled, randomized crossover trial
    • Marcus LS, Hart D, Packer M, et al. Hemodynamic and renal excretory effects of human brain natriuretic peptide infusion in patients with congestive heart failure. A double-blind, placebocontrolled, randomized crossover trial. Circulation. 1996;94:3184-3189. (Pubitemid 26427485)
    • (1996) Circulation , vol.94 , Issue.12 , pp. 3184-3189
    • Marcus, L.S.1    Hart, D.2    Packer, M.3    Yushak, M.4    Medina, N.5    Danziger, R.S.6    Heitjan, D.F.7    Katz, S.D.8
  • 24
    • 0037181511 scopus 로고    scopus 로고
    • Publication Committee for the VMAC Investigators (Vasodilatation in the Management of Acute CHF): Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial
    • Publication Committee for the VMAC Investigators (Vasodilatation in the Management of Acute CHF): Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. JAMA. 2002;287:1531-1540.
    • (2002) JAMA , vol.287 , pp. 1531-1540
  • 25
    • 17144392493 scopus 로고    scopus 로고
    • Short-term risk of death after treatment with nesiritide for decompensated heart failure: A pooled analysis of randomized controlled trials
    • DOI 10.1001/jama.293.15.1900
    • Sackner-Bernstein JD, Kowalski M, Fox M, et al. Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials. JAMA. 2005;293:1900-1905. 26. (Pubitemid 40548187)
    • (2005) Journal of the American Medical Association , vol.293 , Issue.15 , pp. 1900-1905
    • Sackner-Bernstein, J.D.1    Kowalski, M.2    Fox, M.3    Aaronson, K.4
  • 26
    • 33845187599 scopus 로고    scopus 로고
    • Short and long-term mortality with nesiritide
    • DOI 10.1016/j.ahj.2006.07.002, PII S0002870306006326
    • Arora RR, Venkatesh PK, Molnar J. Short and long-term mortality with nesiritide. Am Heart J. 2006;152:1084-1090. (Pubitemid 44854791)
    • (2006) American Heart Journal , vol.152 , Issue.6 , pp. 1084-1090
    • Arora, R.R.1    Venkatesh, P.K.2    Molnar, J.3
  • 27
    • 16344377117 scopus 로고    scopus 로고
    • Risk of worsening renal function with nesiritide in patients with acutely decompensated heart failure
    • DOI 10.1161/01.CIR.0000159340.93220.E4
    • Sackner-Bernstein JD, Skopicki HA, Aaronson KD. Risk of worsening renal function with nesiritide in patients with acutely decompensated heart failure. Circulation. 2005;111:1487-1491. (Pubitemid 40470642)
    • (2005) Circulation , vol.111 , Issue.12 , pp. 1487-1491
    • Sackner-Bernstein, J.D.1    Skopicki, H.A.2    Aaronson, K.D.3
  • 28
    • 80055030711 scopus 로고    scopus 로고
    • The Pink Sheet FDC Reports
    • The Pink Sheet FDC Reports. Chevy Chase, MD. 2005;67(17):3.
    • (2005) Chevy Chase, MD. , vol.67 , Issue.17 , pp. 3
  • 29
    • 0035399986 scopus 로고    scopus 로고
    • Comparison of the occurrence of ventricular arrhythmias in patients with acutely decompensated congestive heart failure receiving dobutamine versus nesiritide therapy
    • DOI 10.1016/S0002-9149(01)01581-8, PII S0002914901015818
    • Burger AJ, Elkayam U, Neibaur MT, et al. Comparison of the occurrence of ventricular arrhythmias in patients with acutely decompensated congestive heart failure receiving dobutamine versus nesiritide therapy. Am J Cardiol. 2001;88:35-39. (Pubitemid 32553889)
    • (2001) American Journal of Cardiology , vol.88 , Issue.1 , pp. 35-39
    • Burger, A.J.1    Elkayam, U.2    Neibaur, M.T.3    Haught, H.4    Ghali, J.5    Horton, D.P.6    Aronson, D.7
  • 30
    • 0037028855 scopus 로고    scopus 로고
    • Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure
    • DOI 10.1016/S0735-1097(01)01818-6, PII S0735109701018186
    • Silver MA, Horton DP, Ghali JK, et al. Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure. J Am Coll Cardiol. 2002;39:798-803. (Pubitemid 34185326)
    • (2002) Journal of the American College of Cardiology , vol.39 , Issue.5 , pp. 798-803
    • Silver, M.A.1    Horton, D.P.2    Ghali, J.K.3    Elkayam, U.4
  • 32
    • 53949095477 scopus 로고    scopus 로고
    • Safety and efficacy of outpatient nesiritide in patients with advanced heart failure: Results of the Second Follow-Up Serial Infusions of Nesiritide (FUSION II) trial
    • Yancy CW, Krum H, Massie BM, et al. Safety and efficacy of outpatient nesiritide in patients with advanced heart failure: results of the Second Follow-Up Serial Infusions of Nesiritide (FUSION II) trial. Circ Heart Fail. 2008;1(1):9-16.
    • (2008) Circ Heart Fail. , vol.1 , Issue.1 , pp. 9-16
    • Yancy, C.W.1    Krum, H.2    Massie, B.M.3
  • 33
    • 33947407278 scopus 로고    scopus 로고
    • The Second Follow-up Serial Infusions of Nesiritide (FUSION II) trial for advanced heart failure: Study rationale and design
    • DOI 10.1016/j.ahj.2007.02.004, PII S0002870307001366
    • Yancy CW, Krum H, Massie BM, et al. The second follow-up serial infusions of nesiritide (FUSION II) trial for advanced heart failure: study rationale and design. Am Heart J. 2007;153 (4):478-484. (Pubitemid 46442809)
    • (2007) American Heart Journal , vol.153 , Issue.4 , pp. 478-484
    • Yancy, C.W.1    Krum, H.2    Massie, B.M.3    Silver, M.A.4    Stevenson, L.W.5    Cheng, M.6    Kim, S.S.7    Evans, R.8
  • 34
    • 33745674089 scopus 로고    scopus 로고
    • Potential Applications of Outpatient Nesiritide Infusions in Patients With Advanced Heart Failure and Concomitant Renal Insufficiency (from the Follow-Up Serial Infusions of Nesiritide [FUSION I] Trial)
    • DOI 10.1016/j.amjcard.2006.01.081, PII S0002914906006734
    • Yancy CW, Singh A. Potential applications of outpatient nesiritide infusions in patients with advanced heart failure and concomitant renal insufficiency (from the Follow-Up Serial Infusions of Nesiritide [FUSION I] trial). Am J Cardiol. 2006;98(2):226-229. (Pubitemid 43975501)
    • (2006) American Journal of Cardiology , vol.98 , Issue.2 , pp. 226-229
    • Yancy, C.W.1    Singh, A.2
  • 35
    • 17144392549 scopus 로고    scopus 로고
    • Treatment with B-type natriuretic peptide for chronic decompensated heart failure: Insights learned from the Follow-Up Serial Infusion of Nesiritide (FUSION) trial
    • DOI 10.1007/s10741-005-6132-9
    • Yancy CW. Treatment with B-type natriuretic peptide for chronic decompensated heart failure: insights learned from the follow-up serial infusion of nesiritide (FUSION) trial. Heart Fail Rev. 2004;9 (3):209-216. (Pubitemid 40521283)
    • (2005) Heart Failure Reviews , vol.9 , Issue.3 , pp. 209-216
    • Yancy, C.W.1
  • 38
    • 80055059466 scopus 로고    scopus 로고
    • Panel of Cardiology Experts Provides Recommendations to Scios Regarding NATRECOR [press release], CA; June 13
    • Panel of Cardiology Experts Provides Recommendations to Scios Regarding NATRECOR [press release]. Fremont, CA; June 13, 2005.
    • (2005) Fremont
  • 39
    • 58649088449 scopus 로고    scopus 로고
    • Rationale and design of the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure Trial (ASCENDHF)
    • Hernandez AF, O'Connor CM, Starling RC, et al. Rationale and design of the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure Trial (ASCENDHF). Am Heart J. 2009;157:271-277.
    • (2009) Am Heart J. , vol.157 , pp. 271-277
    • Hernandez, A.F.1    O'Connor, C.M.2    Starling, R.C.3
  • 40
    • 58749092123 scopus 로고    scopus 로고
    • Standardizing care for acute decompensated heart failure in a large megatrial: The approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND- HF)
    • Ezekowitz JA, Hernandez AF, Starling RC, et al. Standardizing care for acute decompensated heart failure in a large megatrial: the approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND- HF). Am Heart J. 2009;157:219-228.
    • (2009) Am Heart J. , vol.157 , pp. 219-228
    • Ezekowitz, J.A.1    Hernandez, A.F.2    Starling, R.C.3
  • 41
    • 48749115604 scopus 로고    scopus 로고
    • A Canadian context for the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF) trial
    • Armstrong PW, Rouleau JL. A Canadian context for the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF) trial. Can J Cardiol. 2008;24(Suppl B):30B-32B.
    • (2008) Can J Cardiol. , vol.24 , Issue.SUPPL. B
    • Armstrong, P.W.1    Rouleau, J.L.2
  • 42
    • 79551507299 scopus 로고    scopus 로고
    • Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial (ASCEND-HF) - Nesiritide or placebo for improved symptoms and outcomes in acute decompensated HF
    • November 14,2010, Chicago, IL (Late- Breaking Clinical Trials I)
    • Hernandez AF (2010) Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial (ASCEND-HF) - nesiritide or placebo for improved symptoms and outcomes in acute decompensated HF. American Heart Association 2010 Scientific Sessions, November 14, 2010, Chicago, IL (Late- Breaking Clinical Trials I).
    • (2010) American Heart Association 2010 Scientific Sessions
    • Hernandez, A.F.1
  • 43
    • 79551534844 scopus 로고    scopus 로고
    • Late-breaking clinical trials presented at the American Heart Association Congress in Chicago 2010
    • Gensch C, Hoppe U, Bohm M, et al. Late-breaking clinical trials presented at the American Heart Association Congress in Chicago 2010. Clin Res Cardiol. 2011;100:1-9.
    • (2011) Clin Res Cardiol. , vol.100 , pp. 1-9
    • Gensch, C.1    Hoppe, U.2    Bohm, M.3
  • 44
    • 77955987579 scopus 로고    scopus 로고
    • Nesiritide in acute decompensated heart failure: A pooled analysis of randomized controlled trials
    • Abraham WT, Trupp RJ, Jarjoura D. Nesiritide in acute decompensated heart failure: a pooled analysis of randomized controlled trials. Clin Cardiol. 2010; 33(8):484-489.
    • (2010) Clin Cardiol. , vol.33 , Issue.8 , pp. 484-489
    • Abraham, W.T.1    Trupp, R.J.2    Jarjoura, D.3
  • 45
    • 79952193097 scopus 로고    scopus 로고
    • Renal function and neurohormonal changes following intravenous infusions of nitroglycerin versus nesiritide in patients with acute decompensated heart failure
    • Chow SL, O'Barr SA, Peng J, et al. Renal function and neurohormonal changes following intravenous infusions of nitroglycerin versus nesiritide in patients with acute decompensated heart failure. J Card Fail. 2011; 17(3):181-187.
    • (2011) J Card Fail. , vol.17 , Issue.3 , pp. 181-187
    • Chow, S.L.1    O'Barr, S.A.2    Peng, J.3
  • 46
    • 0035748229 scopus 로고    scopus 로고
    • Nesiritide: Practical guide to its safe and effective use
    • Fonarow GC. Nesiritide: practical guide to its safe and effective use. Rev Cardiovasc Med. 2001;2 Suppl 2:S32.
    • (2001) Rev Cardiovasc Med. , vol.2 , Issue.SUPPL. 2
    • Fonarow, G.C.1
  • 47
    • 0036124707 scopus 로고    scopus 로고
    • How to use nesiritide in treating decompensated heart failure
    • Mills RM, Hobbs RE. How to use nesiritide in treating decompensated heart failure. Cleve Clin J Med. 2002;69:252-256. (Pubitemid 34228961)
    • (2002) Cleveland Clinic Journal of Medicine , vol.69 , Issue.3 , pp. 252-256
    • Mills, R.M.1    Hobbs, R.E.2
  • 48
    • 80055040937 scopus 로고    scopus 로고
    • The Pink Sheet FDC Reports
    • The Pink Sheet FDC Reports. Chevy Chase, MD. 2005;67(29):9.
    • (2005) Chevy Chase, MD , vol.67 , Issue.29 , pp. 9
  • 49
    • 0035851516 scopus 로고    scopus 로고
    • Nesiritide for decompensated congestive heart failure
    • Nesiritide for decompensated congestive heart failure. Med Lett Drugs Ther. 2001;43:100-101.
    • (2001) Med Lett Drugs Ther. , vol.43 , pp. 100-101
  • 50
    • 34748837363 scopus 로고    scopus 로고
    • Low dose nesiritide and the preservation of renal function in patients with renal dysfunction undergoing cardiopulmonary-bypass surgery: A double-blind placebo-controlled pilot study
    • I-134-I-138
    • Chen HH, Sundt TM, Cook DJ, et al. Low dose nesiritide and the preservation of renal function in patients with renal dysfunction undergoing cardiopulmonary-bypass surgery: a double-blind placebo-controlled pilot study. Circulation. 2007;116:I-134-I-138.
    • (2007) Circulation , vol.116
    • Chen, H.H.1    Sundt, T.M.2    Cook, D.J.3
  • 51
    • 33646916616 scopus 로고    scopus 로고
    • Nonhypotensive Low-Dose Nesiritide Has Differential Renal Effects Compared With Standard-Dose Nesiritide in Patients With Acute Decompensated Heart Failure and Renal Dysfunction
    • DOI 10.1016/j.jacc.2006.03.013, PII S0735109706006322
    • Riter HG, Redfield MM, Burnett JC, et al. Nonhypotensive lowdose nesiritide has differential renal effects compared with standard-dose nesiritide in patients with acute decompensated heart failure and renal dysfunction. J Am Coll Cardiol. 2006;47:2334-2335. (Pubitemid 43795074)
    • (2006) Journal of the American College of Cardiology , vol.47 , Issue.11 , pp. 2334-2335
    • Riter, H.G.1    Redfield, M.M.2    Burnett, J.C.3    Chen, H.H.4
  • 53
    • 0031746435 scopus 로고    scopus 로고
    • Systemic hemodynamic, neurohormonal, and renal effects of a steady- state infusion of human brain natriuretic peptide in patients with hemodynamically decompensated heart failure
    • DOI 10.1016/S1071-9164(98)90506-1
    • Abraham WT, Lowes BD, Ferguson DA, et al. Systemic hemodynamic, neurohormonal, and renal effects of a steadystate infusion of human brain natriuretic peptide in patients with hemodynamically decompensated heart failure. J Card Fail. 1998;4:37-44. (Pubitemid 28252539)
    • (1998) Journal of Cardiac Failure , vol.4 , Issue.1 , pp. 37-44
    • Abraham, W.T.1    Lowes, B.D.2    Ferguson, D.A.3    Odom, J.4    Kim, J.K.5    Robertson, A.D.6    Bristow, M.R.7    Schrier, R.W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.