-
1
-
-
34548208677
-
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
-
Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, et al. (2007) Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol 5: e201.
-
(2007)
PLoS Biol
, vol.5
-
-
Chambers, S.M.1
Shaw, C.A.2
Gatza, C.3
Fisk, C.J.4
Donehower, L.A.5
-
2
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
Rossi DJ, Bryder D, Zahn JM, Ahlenius H, Sonu R, et al. (2005) Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A 102: 9194-9199.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9194-9199
-
-
Rossi, D.J.1
Bryder, D.2
Zahn, J.M.3
Ahlenius, H.4
Sonu, R.5
-
3
-
-
0024364675
-
GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies
-
McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF, (1989) GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest 84: 92-99.
-
(1989)
J Clin Invest
, vol.84
, pp. 92-99
-
-
McEver, R.P.1
Beckstead, J.H.2
Moore, K.L.3
Marshall-Carlson, L.4
Bainton, D.F.5
-
4
-
-
4644276687
-
Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in mice
-
Pelletier SD, Hong DS, Hu Y, Liu Y, Li S, (2004) Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in mice. Blood 104: 2163-2171.
-
(2004)
Blood
, vol.104
, pp. 2163-2171
-
-
Pelletier, S.D.1
Hong, D.S.2
Hu, Y.3
Liu, Y.4
Li, S.5
-
5
-
-
0033519238
-
The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity
-
Li S, Ilaria RL Jr, Million RP, Daley GQ, Van Etten RA, (1999) The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. J Exp Med 189: 1399-1412.
-
(1999)
J Exp Med
, vol.189
, pp. 1399-1412
-
-
Li, S.1
Ilaria Jr., R.L.2
Million, R.P.3
Daley, G.Q.4
Van Etten, R.A.5
-
6
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, Buchdunger E, Warmuth M, et al. (2004) Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 36: 453-461.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
Buchdunger, E.4
Warmuth, M.5
-
7
-
-
34547137932
-
Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells
-
Peng C, Brain J, Hu Y, Goodrich A, Kong L, et al. (2007) Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells. Blood 110: 678-685.
-
(2007)
Blood
, vol.110
, pp. 678-685
-
-
Peng, C.1
Brain, J.2
Hu, Y.3
Goodrich, A.4
Kong, L.5
-
8
-
-
77449117864
-
PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice
-
Peng C, Chen Y, Yang Z, Zhang H, Osterby L, et al. (2010) PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice. Blood 115: 626-635.
-
(2010)
Blood
, vol.115
, pp. 626-635
-
-
Peng, C.1
Chen, Y.2
Yang, Z.3
Zhang, H.4
Osterby, L.5
-
9
-
-
67649861052
-
Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia
-
Chen Y, Hu Y, Zhang H, Peng C, Li S, (2009) Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia. Nat Genet 41: 783-792.
-
(2009)
Nat Genet
, vol.41
, pp. 783-792
-
-
Chen, Y.1
Hu, Y.2
Zhang, H.3
Peng, C.4
Li, S.5
-
10
-
-
33750937577
-
Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice
-
Hu Y, Swerdlow S, Duffy TM, Weinmann R, Lee FY, et al. (2006) Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice. Proc Natl Acad Sci U S A 103: 16870-16875.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16870-16875
-
-
Hu, Y.1
Swerdlow, S.2
Duffy, T.M.3
Weinmann, R.4
Lee, F.Y.5
-
11
-
-
36749048070
-
Targeting selectins and selectin ligands in inflammation and cancer
-
Barthel SR, Gavino JD, Descheny L, Dimitroff CJ, (2007) Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets 11: 1473-1491.
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 1473-1491
-
-
Barthel, S.R.1
Gavino, J.D.2
Descheny, L.3
Dimitroff, C.J.4
-
12
-
-
34547813033
-
P-selectin: a common therapeutic target for cardiovascular disorders, inflammation and tumour metastasis
-
Ludwig RJ, Schon MP, Boehncke WH, (2007) P-selectin: a common therapeutic target for cardiovascular disorders, inflammation and tumour metastasis. Expert Opin Ther Targets 11: 1103-1117.
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 1103-1117
-
-
Ludwig, R.J.1
Schon, M.P.2
Boehncke, W.H.3
-
13
-
-
0028860321
-
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin
-
Moore KL, Patel KD, Bruehl RE, Li F, Johnson DA, et al. (1995) P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. J Cell Biol 128: 661-671.
-
(1995)
J Cell Biol
, vol.128
, pp. 661-671
-
-
Moore, K.L.1
Patel, K.D.2
Bruehl, R.E.3
Li, F.4
Johnson, D.A.5
-
14
-
-
36249018885
-
Hematopoietic stem cell aging: wrinkles in stem cell potential
-
Chambers SM, Goodell MA, (2007) Hematopoietic stem cell aging: wrinkles in stem cell potential. Stem Cell Rev 3: 201-211.
-
(2007)
Stem Cell Rev
, vol.3
, pp. 201-211
-
-
Chambers, S.M.1
Goodell, M.A.2
-
15
-
-
77955658323
-
Stem cells and the aging hematopoietic system
-
Beerman I, Maloney WJ, Weissmann IL, Rossi DJ, (2010) Stem cells and the aging hematopoietic system. Curr Opin Immunol 22: 500-506.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 500-506
-
-
Beerman, I.1
Maloney, W.J.2
Weissmann, I.L.3
Rossi, D.J.4
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